Steroid Injection Side Effects on Skin Health - Dermatology

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Side effects of steroid injections on the skin?


About four years ago, I experienced swelling and pain in my buttocks.
I visited a dermatologist who diagnosed it as a sebaceous cyst and administered a corticosteroid injection to reduce the swelling.
After some time, I noticed that the area had developed a slight indentation and felt somewhat rough to the touch.
I consulted another physician who suggested that it appeared to be a post-injury sequela.
Recently, the indented area has started to regain some tissue, but the roughness remains.
I am now concerned about whether there could be any other long-term complications.

Andy, 20~29 year old female. Ask Date: 2016/01/13

Dr. Wu Yuxin reply Dermatology


The indentation may not necessarily be caused by steroid injections; it could also be due to the formation of scar tissue.
The rough texture is typically a result of inflammation and will usually improve over time.

Reply Date: 2016/01/13

More Info


When it comes to understanding the side effects of steroid injections, particularly in relation to skin health, it is essential to consider both the immediate and long-term consequences of such treatments. In your case, it seems that you received a steroid injection for a lipoma, which is a benign tumor made of fat tissue. While steroid injections can effectively reduce inflammation and swelling, they can also lead to various skin changes, including atrophy, textural changes, and potential scarring.

Steroids, particularly when injected, can cause localized skin thinning or atrophy. This occurs because steroids inhibit collagen synthesis and can lead to a reduction in the overall thickness of the skin. The rough texture you are experiencing may be a result of this atrophy, as the skin loses its structural integrity. Additionally, the injection itself can sometimes cause localized damage to the skin and underlying tissues, leading to a condition known as "steroid-induced atrophy," which can manifest as a depression or indentation in the skin.

It is also worth noting that the area where the injection was administered may have experienced some trauma, which can contribute to the rough texture and indentation. The body’s healing process can sometimes lead to the formation of fibrous tissue, which may feel different from the surrounding skin. The fact that you have noticed some improvement, with a bit of "meat" returning to the area, is a positive sign. This suggests that your body is healing and attempting to restore normal tissue structure.

However, it is understandable to be concerned about potential long-term effects. While some changes may be permanent, many individuals experience gradual improvement over time as the body continues to heal. The roughness may diminish, and the skin may regain some of its original texture. It is also important to consider that individual responses to steroid injections can vary widely based on factors such as skin type, the amount of steroid used, and the specific area treated.

If you are worried about the ongoing roughness or any other changes in the area, it is advisable to consult with a dermatologist. They can assess the site and determine whether any further treatment is necessary. Options may include topical treatments to improve skin texture, such as retinoids or other agents that promote collagen production. In some cases, dermatologists may recommend procedures like microneedling or laser therapy to enhance skin appearance and texture.

In summary, while steroid injections can lead to side effects such as skin atrophy and textural changes, the body often has a remarkable ability to heal. Your observation of some improvement is encouraging, but ongoing monitoring and consultation with a healthcare professional are essential to address any concerns and to explore potential treatment options for improving the skin's appearance. Always remember that open communication with your healthcare provider is key to managing any side effects and ensuring the best possible outcomes for your skin health.

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