Knee Pain: Early Onset Osteoarthritis in Young Adults - Orthopedics

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Knee problems


Hello Doctor: I injured my right thigh in September of last year, and two weeks later, I suddenly started experiencing knee pain (initially, it felt like there was air inside my knee when standing, which was quite uncomfortable).
Eventually, I found it difficult to squat (with pain on the inner side of my knee when squatting), but walking was normal and did not cause pain.
Initially, after an X-ray, the doctor mentioned that there was a difference in the spacing of my knee joints and advised me to perform strength training at home.
However, there was no improvement.
Recently, I underwent an MRI, and the doctor informed me that I have early-stage osteoarthritis.
But I am only 23 years old.
I would like to ask the doctor why I am experiencing osteoarthritis in my knee, and I also want to inquire if it is possible that I have patellar chondromalacia? (Currently, my symptoms include no issues while walking, but I feel pain on the inner side of my knee when standing, which is very uncomfortable.
At times, it feels like my knee is giving way, making it uncomfortable to stand for even a second, and I also experience inner knee pain when squatting.) I apologize for the many questions, and I appreciate your help.
Thank you very much.

W123, 20~29 year old female. Ask Date: 2016/01/20

Dr. Shi Guozheng reply Orthopedics


Based on your age, the likelihood of osteoarthritis is quite low; the pain is usually caused by inflammation of the ligaments or tendons near the knee joint.
Medication, rest, and rehabilitation typically lead to improvement.
Chondromalacia generally occurs at the patellofemoral joint, and the treatment methods are similar.

Reply Date: 2016/01/20

More Info


Knee pain in young adults can be a complex issue, often stemming from various underlying conditions. Your symptoms, particularly the onset of pain after a thigh injury and the subsequent diagnosis of early-onset osteoarthritis at the age of 23, warrant a thorough understanding of the potential causes and treatment options.

Firstly, it's important to recognize that osteoarthritis (OA) is typically associated with aging and wear-and-tear on the joints. However, early-onset OA can occur in younger individuals due to several factors, including previous injuries, genetic predisposition, obesity, and overuse. In your case, the initial thigh injury may have altered your knee mechanics, leading to uneven stress on the joint surfaces. This can accelerate cartilage degeneration, resulting in the symptoms you are experiencing.

The sensation of "air" in the knee and discomfort while standing could indicate issues with the joint's stability or the presence of fluid accumulation, which is common in inflammatory conditions. The fact that you experience pain primarily when standing or squatting suggests that certain movements may exacerbate the underlying joint issues. It’s also worth noting that the feeling of the knee "running away" or instability can be indicative of ligamentous laxity or meniscal involvement, which should be evaluated further.

Regarding your concern about patellar chondromalacia (softening of the cartilage under the kneecap), this condition can indeed coexist with osteoarthritis, especially if there has been a history of trauma or misalignment. The pain you describe on the inner side of the knee during specific movements could be related to patellar tracking issues, which are common in young athletes and can lead to chondromalacia.

To address your condition, a multifaceted approach is recommended:
1. Physical Therapy: Engaging in a structured physical therapy program can help strengthen the muscles around the knee, improve stability, and enhance overall joint function. Focus on exercises that target the quadriceps, hamstrings, and hip muscles, as these play a crucial role in knee mechanics.

2. Activity Modification: It’s essential to avoid activities that exacerbate your symptoms. High-impact sports or exercises that involve deep squatting may need to be limited until your knee stabilizes.

3. Weight Management: If applicable, maintaining a healthy weight can reduce stress on the knee joint, potentially alleviating pain and slowing the progression of osteoarthritis.

4. Pain Management: Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) can help manage pain and inflammation. However, it’s crucial to consult with your healthcare provider before starting any medication.

5. Injections: In some cases, corticosteroid injections or hyaluronic acid injections may be considered to reduce inflammation and provide temporary relief.

6. Surgical Options: If conservative measures fail and your symptoms persist, surgical options such as arthroscopy or realignment procedures may be explored, especially if there is significant structural damage.

Lastly, regular follow-ups with an orthopedic specialist or a rheumatologist can help monitor your condition and adjust your treatment plan as necessary. Early intervention and a proactive approach can significantly improve your quality of life and potentially slow the progression of osteoarthritis.

In conclusion, while early-onset osteoarthritis at a young age can be concerning, understanding the underlying causes and implementing a comprehensive treatment strategy can help manage your symptoms effectively. Always consult with your healthcare provider for personalized advice and treatment options tailored to your specific situation.

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