Persistent Scabies: Seeking Effective Treatment and Management Tips - Dermatology

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Scabies has not improved?


Since early May of last year, I have been experiencing recurrent scabies that won't resolve.
Currently, I am using Permethrin cream.
Can you suggest a treatment method? It's really frustrating.
A few days ago, I was almost better! Many of the rashes have turned brown and are not very itchy, but there is still a nodule in the genital area that hasn't shown any signs of shrinking.
Often, every two to three days, new bumps appear on my body that are itchy.
Is this a recurrence? Can I apply Permethrin cream every day? Or do you recommend how to use this medication, and how long should I leave it on before washing it off? I'm feeling quite lost.

Fanrao Ren, 30~39 year old female. Ask Date: 2016/02/02

Dr. Wu Yuxin reply Dermatology


Scabicide is not recommended for daily use and should remain on the skin for at least 8 hours each time.
If new rashes continue to appear, it indicates incomplete treatment, which may be due to incorrect application of the medication, insufficient disinfection of clothing, or even the possibility of drug resistance.
It is advisable to seek medical attention promptly.

Reply Date: 2016/02/02

More Info


Persistent scabies can be a frustrating and challenging condition to manage, especially when it seems to recur despite treatment. Scabies is caused by the Sarcoptes scabiei mite, which burrows into the skin, leading to intense itching and a rash. The persistence of symptoms, even after treatment, can be due to several factors including reinfestation, inadequate treatment application, or the presence of secondary infections.


Treatment Options
1. Permethrin Cream: This is the most commonly prescribed topical treatment for scabies. It is usually applied from the neck down to the toes and left on for 8 to 14 hours before washing off. It is important to apply it to all areas of the body, including under the nails and in skin folds, to ensure that all mites are eradicated.

2. Ivermectin: For cases that are resistant to topical treatments or in situations where there are multiple infestations (such as in a household or institutional setting), oral ivermectin may be prescribed. This medication is taken as a single dose and may be repeated after a week if symptoms persist.

3. Benzyl Benzoate: This is another topical treatment option that can be effective against scabies. It is typically applied in a similar manner to permethrin.


Application Guidelines
- Frequency of Application: Permethrin cream should not be applied daily. Typically, it is applied once and may be repeated after one week if symptoms persist. Overuse can lead to skin irritation.


- Washing Off: After applying the cream, it should be washed off after the recommended time (8-14 hours). Ensure that you follow the instructions provided by your healthcare provider.

- Reinfestation Prevention: To prevent reinfestation, it is crucial to treat all close contacts simultaneously, as scabies is highly contagious. Additionally, wash all clothing, bedding, and towels in hot water and dry them on a hot cycle to kill any mites that may be present.


Managing Symptoms
- Itching Relief: The itching associated with scabies can persist for several weeks even after the mites have been eradicated. Antihistamines or topical corticosteroids may be recommended to help alleviate itching.

- Monitoring for Secondary Infections: If you notice any signs of infection (such as increased redness, swelling, or pus), it is important to consult your healthcare provider for further evaluation and possible antibiotic treatment.


When to Seek Further Help
If you continue to experience symptoms despite following treatment protocols, it may be necessary to revisit your healthcare provider. They may consider alternative diagnoses, such as eczema or other skin conditions that can mimic scabies, or they may recommend a different treatment approach.

In summary, managing persistent scabies requires a comprehensive approach that includes effective treatment, proper application techniques, and preventive measures to avoid reinfestation. If you have further questions or concerns, don’t hesitate to reach out to your healthcare provider for personalized advice and support.

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