Liver Health: Addressing Concerns About Fibrosis and Hepatitis - Gastroenterology and Hepatology

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Liver issues?


Hello doctor, I tested negative for Hepatitis B surface antigen, positive for surface antibodies, and positive for core antibodies.
My antibodies were not produced by vaccination.
My Hepatitis C level is 0.07.
My outpatient doctor mentioned that my liver is rough, indicating liver fibrosis, and that I can only be monitored.
Is that correct? I am in a lot of pain every day and am very worried about the possibility of cirrhosis.
Is there a chance for improvement? What should I pay attention to in my daily life? Thank you.

Piqiu, 40~49 year old female. Ask Date: 2016/02/18

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: (1) Hepatitis B surface antigen negative and surface antibody positive: This indicates that there is no Hepatitis B carrier status and that immunity is present.
(2) Core antibody positive: This signifies a past infection with Hepatitis B, but the individual has since recovered.
(3) Hepatitis C level at 0.07 may require reference to standard values.
(If positive: it is also a very low positive reaction, and consideration can be given to testing for Hepatitis C viral load).
(4) Liver fibrosis has varying degrees; you may want to clarify the extent of fibrosis.
Mild fibrosis is still far from cirrhosis, so there is no need for excessive concern.
(5) Pay attention to lifestyle habits, ensure adequate sleep, avoid taking medications indiscriminately, and do not consume alcohol excessively.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2016/02/18

More Info


Understanding liver health is crucial, especially when dealing with conditions like hepatitis and fibrosis. Based on your test results, it appears that you have a positive Hepatitis B surface antibody (Anti-HBs) and a positive core antibody (Anti-HBc), while the Hepatitis B surface antigen (HBsAg) is negative. This indicates that you have either cleared a past Hepatitis B infection or have been vaccinated against it. The presence of the core antibody suggests that you may have been exposed to the virus at some point, but the absence of the surface antigen indicates that the virus is not currently active in your system.

Regarding your concerns about liver fibrosis, it is essential to understand that liver fibrosis is the result of chronic liver injury, which can be caused by various factors, including viral hepatitis, alcohol consumption, and non-alcoholic fatty liver disease (NAFLD). Fibrosis is a progressive condition, and if left unchecked, it can lead to cirrhosis, which is a more severe scarring of the liver that can impair its function.

Your doctor’s recommendation to "only track" the condition is common in cases of mild to moderate fibrosis. Regular monitoring through blood tests and imaging studies, such as ultrasound or elastography, can help assess the progression of fibrosis. In some cases, if the fibrosis is detected early and the underlying cause is addressed, there is potential for improvement. For instance, if your liver fibrosis is related to lifestyle factors, making changes such as adopting a healthier diet, increasing physical activity, and avoiding alcohol can significantly impact liver health.

Here are some lifestyle modifications you can consider to support your liver health:
1. Dietary Changes: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid high-fat, sugary, and processed foods, as they can contribute to fatty liver disease and worsen fibrosis.

2. Regular Exercise: Aim for at least 150 minutes of moderate-intensity aerobic activity each week. Exercise can help reduce liver fat and improve overall liver function.

3. Avoid Alcohol: Alcohol can exacerbate liver damage, especially if you have existing fibrosis. It is advisable to limit or completely avoid alcohol consumption.

4. Weight Management: If you are overweight or obese, losing weight can significantly improve liver health and reduce fibrosis. Even a modest weight loss of 5-10% can have beneficial effects.

5. Regular Medical Check-ups: Continue to have regular follow-ups with your healthcare provider to monitor liver function and fibrosis progression. Discuss any new symptoms or concerns you may have.

6. Vaccinations: Ensure you are vaccinated against Hepatitis A and B if you haven't already, as these can prevent further liver complications.

7. Avoid Hepatotoxic Substances: Be cautious with medications and supplements that can harm the liver. Always consult your doctor before starting any new medication or supplement.

In summary, while your current situation may seem daunting, there are steps you can take to manage your liver health actively. Regular monitoring and lifestyle changes can help mitigate the risk of progression to cirrhosis. If you have persistent pain or other concerning symptoms, it is essential to communicate these with your healthcare provider for further evaluation and management. Remember, early intervention and lifestyle modifications can make a significant difference in your liver health outcomes.

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