Can I Complete My Hepatitis B Vaccine During Pregnancy? - Gastroenterology and Hepatology

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Hepatitis B vaccination administration


Hello Dr.
Chen, I would like to ask if I can continue with the administration of the third dose of the hepatitis B vaccine.
I have already completed the first two doses, with the third dose scheduled for March 28, 2016.
However, I am currently 13 weeks pregnant.
Thank you!

Xiao Jun, 30~39 year old female. Ask Date: 2016/03/14

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Based on the current information, it is possible.

Reply Date: 2016/03/14

More Info


Yes, you can complete your Hepatitis B vaccination during pregnancy. Current medical guidelines indicate that it is generally safe for pregnant women to receive the Hepatitis B vaccine. The vaccine is made from a non-infectious component of the virus, which means it does not pose a risk to the fetus.
The Hepatitis B vaccine is typically administered in a series of three doses. The first dose is given at a chosen time, the second dose is administered one month later, and the third dose is given six months after the first dose. If you have already received the first two doses, it is advisable to complete the series with the third dose, even during pregnancy.
Completing the vaccination series is important for several reasons. First, it ensures that you develop adequate immunity against Hepatitis B, which is crucial for your health and the health of your baby. Hepatitis B is a serious liver infection that can lead to chronic disease and other complications. By ensuring that you are vaccinated, you reduce the risk of contracting the virus, which can be transmitted to your baby during childbirth if you are a carrier.

Moreover, if you are a Hepatitis B carrier, it is essential to follow the recommended protocols for managing the condition during pregnancy. This includes regular monitoring and possibly antiviral treatment to reduce the viral load, which can help minimize the risk of transmission to your newborn. The Centers for Disease Control and Prevention (CDC) recommends that all infants born to Hepatitis B-positive mothers receive the Hepatitis B vaccine and Hepatitis B immune globulin (HBIG) within 12 hours of birth to prevent infection.

Regarding your concern about the timing of the vaccine and its effects on pregnancy, studies have shown that there is no evidence to suggest that the Hepatitis B vaccine adversely affects pregnancy outcomes or fetal development. The vaccine is classified as a Category B medication, which means that animal reproduction studies have not shown a risk to the fetus, and there are no adequate and well-controlled studies in pregnant women.

If you have already received the first two doses and are now pregnant, you should consult with your healthcare provider about the timing of your third dose. It is generally recommended to continue with the vaccination schedule unless your healthcare provider advises otherwise based on your specific health circumstances.

In summary, completing your Hepatitis B vaccination during pregnancy is not only safe but also beneficial for your health and the health of your baby. It is crucial to discuss any concerns with your healthcare provider, who can provide personalized advice based on your medical history and current health status.

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