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Does Immunoglobulin Treatment Affect Vaccine Efficacy in Rare Diseases?

Will the effect of administering immunoglobulin and vaccines become ineffective? Dear Dr. Hsieh, After administering immunoglobulin, does it diminish the effectiveness of vaccines received within the previous six months? Our child has Kawasaki disease and received the varicella...


Dr. Xie Kaisheng reply Rare Disease
Because immunoglobulins can neutralize live vaccines, rendering them ineffective, if a live attenuated vaccine (including oral polio vaccine, measles vaccine, measles-mumps-rubella (MMR) vaccine, and varicella vaccine) is administered within a certain period before or after recei...

[Read More] Does Immunoglobulin Treatment Affect Vaccine Efficacy in Rare Diseases?


Understanding Elevated Bilirubin Levels in Newborns: When to Seek Further Care

Liver and gallbladder diseases The baby is currently over one month old, but has a high bilirubin level. The first test showed T-BILIRUBIN 7.2, DIRECT-BILIRUBIN 3.8; the second test showed T-BILIRUBIN 7.1, BILIRUBIN 3.6; and the third test showed T-BILIRUBIN 5.6, BILIRUBIN 3.1. I...


Dr. Xie Kaisheng reply Rare Disease
Based on your description, your baby is experiencing pathological jaundice, indicating that there is an issue with the production and processing of bilirubin in their body, which requires further evaluation and treatment. Generally, neonatal jaundice should be closely monitored u...

[Read More] Understanding Elevated Bilirubin Levels in Newborns: When to Seek Further Care


Understanding Chest Pain While Breathing: A Rare Condition Explained

Sometimes, there is a sharp pain around the heart when breathing? I am currently in my second year of high school. Since I was in the third year of junior high, I have occasionally felt a sharp pain around my heart when I breathe. During these episodes, I tend to pat my chest, wh...


Dr. Xie Kaisheng reply Rare Disease
Anonymous High School Student: Hello, thank you for your email inquiry. Chest pain is a common condition in pediatric cardiology, and its possible causes include heart disease, costochondritis, gastrointestinal disorders, pleuritis, asthma, and thoracic diseases, among others. A ...

[Read More] Understanding Chest Pain While Breathing: A Rare Condition Explained