C-reactive protein, Internal Medicine FAQ

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Understanding RA Factor Changes and Related Health Concerns

Rheumatoid Arthritis - Inquiry about Rheumatoid Factor and Other Related Data? Hello, Doctor Gao. I apologize for the lengthy message. Here are my health examination data from three tests conducted at the same laboratory: - Date: 2023/11/11, 2024/6/15, (2024/4/30) - ALT/SGPT (L...


Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Here are my responses: 1. I underwent tests related to immune system diseases at a regional hospital in December 2023, and my rheumatoid arthritis (RA) factor was less than 5 at that time. Additionally, the measurement taken on April 30, 2024,...

[Read More] Understanding RA Factor Changes and Related Health Concerns


Understanding Juvenile Ankylosing Spondylitis Symptoms and Diagnosis

Symptoms of juvenile ankylosing spondylitis? Hello Doctor: My son is 14 years old (in the second year of junior high school). Three months ago, he experienced unexplained swelling in the second joint of his toe, with no other discomfort. At that time, the doctor ordered blood tes...


Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my thoughts: 1. We will not retest for HLA-B27. 2. If the inflammatory markers are normal (such as CRP and ESR), and there is only swelling in the toes without other symptoms, we might consider using anti-inflammatory pain relief medic...

[Read More] Understanding Juvenile Ankylosing Spondylitis Symptoms and Diagnosis


Understanding Autoimmune Hepatitis: Symptoms, Treatment, and Concerns

Autoimmune hepatitis Hello Doctor: At the end of March this year, I sought consultation in the hepatobiliary and gastroenterology department due to fatigue, jaundice, and tea-colored urine. Blood tests showed AST 675, ALT 1077, and total bilirubin 4.6. Subsequent tests for HBsAg ...


Dr. Zeng Guosen Reply:
It is highly recommended to seek medical attention as soon as possible, preferably by returning to your original treating physician's clinic. If the appointments are fully booked, you should be able to request an additional slot with your original doctor. To determine the si...

[Read More] Understanding Autoimmune Hepatitis: Symptoms, Treatment, and Concerns


Understanding Immune System Tests: What Your Results Mean for You

Immune system Anti-Thyroglobulin Antibody (TA) = 13.87 Anti-Nuclear Antibody = Negative at 1:80 C4 Quantitation = 58.46 C3 Quantitation = 137.97 Anti-Thyroid Peroxidase Antibody (AMA) = <3.00 High-Sensitivity C-Reactive Protein (hsCRP) = 0.16 Rheumatoid Factor = 12...


Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Your report shows that only your IgE level is elevated, which is indicative of an allergic condition. If your C4 level is slightly elevated, it is not a concern; C4 can increase when the body is unwell and does not have special significance. I r...

[Read More] Understanding Immune System Tests: What Your Results Mean for You


Post-COVID Joint Pain: Understanding Symptoms and Seeking Early Diagnosis

Joint pain after a confirmed COVID-19 infection? Hello Doctor, I apologize for the lengthy message. I started feeling unwell on November 11th (muscle aches, fever, fatigue, red rashes on limbs, dry eyes, dry mouth). I was diagnosed with COVID-19 on November 13th. On November 16th...


Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Here are my responses: 1. Since the joint discomfort clearly occurred after the blood draw, could it be that the inflammatory markers, ANA, and other indices had not yet shown abnormal trends at that time, and only now can we detect abnormaliti...

[Read More] Post-COVID Joint Pain: Understanding Symptoms and Seeking Early Diagnosis


Distinguishing Between Immune Issues and Menopause Symptoms at 50

How to distinguish between immune issues and menopausal symptoms? Hello, Doctor. I am 50 years and 6 months old. My menstrual cycle was regular until December of last year when it suddenly stopped. Before March of this year, I experienced insomnia, excessive sweating, frequent co...


Dr. Gao Jiankai Reply:
Hello, thank you for your question. Here are my responses: (1) What tests should be done to confirm if there is inflammation or adhesion in the spine? --> X-rays and blood tests are sufficient. If necessary, an MRI may also be arranged. Your physician may have started treatm...

[Read More] Distinguishing Between Immune Issues and Menopause Symptoms at 50


Does Weather Influence CRP Levels in Ankylosing Spondylitis Patients?

Does weather affect CRP levels? Hello Doctor, my son is 20 years old and has been diagnosed with ankylosing spondylitis for 3.5 years. He has been undergoing regular medication treatment for the past 2.5 years and is currently stable. However, I have noticed a peculiar phenomenon...


Dr. Zeng Guosen Reply:
Patients with rheumatic diseases often experience more discomfort during damp and cold seasons, but weather does not affect the CRP (C-reactive protein) levels reported. Medication adjustments can only be made based on symptoms and the levels of CRP. Thank you.

[Read More] Does Weather Influence CRP Levels in Ankylosing Spondylitis Patients?


Understanding the Link Between EB Virus, CMV, and White Blood Cell Counts

The relationship between Epstein-Barr virus (EBV), cytomegalovirus (CMV), and leukocytes? Hello Doctor, I experienced fever along with swollen and painful bilateral inguinal lymph nodes at the beginning of February. I went for a urology examination, and the blood test was done ap...


Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. It is recommended to include the reference ranges for the test results to facilitate interpretation, as different hospitals may use different laboratory equipment, which can lead to variations in normal values. Additionally, although the total w...

[Read More] Understanding the Link Between EB Virus, CMV, and White Blood Cell Counts


Is the Effect of Celecoxib on ESR Less Noticeable Than on CRP?

Is the effect of Xeljanz on lowering ESR less pronounced? Hello Doctor, I am a patient with ankylosing spondylitis and have been diagnosed for 3 years. For the past year, I have been undergoing treatment with Celecoxib. Although my buttock pain symptoms have significantly improve...


Dr. Zeng Guosen Reply:
The ESR (erythrocyte sedimentation rate) can be influenced by many factors aside from inflammation, so it is primarily recommended to refer to CRP (C-reactive protein) levels. You can try substituting different anti-inflammatory and analgesic medications. The results from the WBC...

[Read More] Is the Effect of Celecoxib on ESR Less Noticeable Than on CRP?


Understanding High ESR Levels in Anemia and Ankylosing Spondylitis

Is it because I have anemia that my ESR is often elevated? Hello Doctor: I am a patient with ankylosing spondylitis, 20 years old, and I have been diagnosed for over 2 years. Recently, for the past 7 months, I have been taking Salazopyrin, and during my last two follow-up visits,...


Dr. Zeng Guosen Reply:
1. Hemoglobin (Hb) levels of 13.5 to 14.5 are not the cause of abnormal erythrocyte sedimentation rate (ESR), as ESR can be influenced by many factors in the body. 2. C-reactive protein (CRP) is more important than ESR for monitoring ankylosing spondylitis; symptoms and X-rays a...

[Read More] Understanding High ESR Levels in Anemia and Ankylosing Spondylitis


Concerns About Parasites and Blood Test Results After Undercooked Meat

Suspected parasitic infection and blood test values? Hello, on October 1st, I consumed a steak that was not cooked to the required doneness (I requested medium, but some parts were rare to medium-rare). I am concerned about parasites (specifically, tapeworms) and have since been ...


Dr. Hong Yuanbin Reply:
Hello, 1. The pork tapeworm can also be killed by freezing. 2. Each individual's condition varies significantly, ranging from a few months to several years. 3. Based on your clinical symptoms and blood test results, it currently does not appear to be a parasitic infection. T...

[Read More] Concerns About Parasites and Blood Test Results After Undercooked Meat


Understanding Side Effects of Celecoxib: Gastrointestinal Concerns and More

Side effects of Xeljanz? Hello Doctor: I am a patient with ankylosing spondylitis, currently 20 years old. I started taking Celebrex a year ago, and recently, four days ago, I began experiencing bloody stools. The colorectal surgeon diagnosed it as hemorrhoids and has prescribed ...


Dr. Zeng Guosen Reply:
Hello, netizen. 1) Yes, but Celecoxib is one of the anti-inflammatory pain medications with relatively low bleeding side effects. 2) An ALT level of 34 is within the normal range, so there is no need to worry as long as it is within normal limits. 3) Generally, the CRP test can d...

[Read More] Understanding Side Effects of Celecoxib: Gastrointestinal Concerns and More


Understanding Antinuclear Antibodies and Lupus: A Patient's Guide

Antinuclear antibodies in systemic lupus erythematosus? ANA: Speckled 1:640 HLA-B27: Negative E.S.R: 61 Basophils: 1.0 Eosinophils: 1.0 Hemoglobin (Hb): 11.9 Hematocrit (Hct): 36.1 Lymphocytes: 28.2 Mean Corpuscular Hemoglobin (MCH): 25.3 Mean Corpuscular Hemogl...


Dr. Gao Jiankai Reply:
Hello, thank you for your inquiry. Your question regarding elevated ANA and ESR levels indicates that it is essential to further investigate the cause of the elevated ANA. Additional tests may be necessary to confirm your diagnosis, and I recommend consulting a rheumatologist for...

[Read More] Understanding Antinuclear Antibodies and Lupus: A Patient's Guide


Understanding Rheumatoid Arthritis: Diagnosis, Treatment, and Concerns

Regarding the diagnosis and medication use for rheumatoid arthritis? Dear Director Gao, I apologize for the length of my inquiry and hope you can take the time to clarify my doubts. Thank you! About a year and a half ago, blood tests revealed that my rheumatoid factor (RF) was...


Dr. Gao Jiankai Reply:
Hello, thank you for your questions. Here are my consolidated responses: 1. Can anti-CCP antibodies be present intermittently? (There was a significant difference in test results just five days apart.) Could differences in testing methods cause varying results? Are there differe...

[Read More] Understanding Rheumatoid Arthritis: Diagnosis, Treatment, and Concerns


Understanding Chronic Eczema: Treatment, Management, and Concerns

Chronic eczema consultation? Hello, Doctor. I would like to consult you about psoriasis. About six months ago, I visited a dermatologist who diagnosed it as chronic eczema. The doctor prescribed two ointments for me. Initially, after applying them, I felt that the flaking had dim...


Dr. Hong Yuanbin Reply:
Chronic eczema refers to chronic inflammation of the skin and is not a specific disease. In contrast, the conditions you mentioned, psoriasis and lupus, are specific diseases that must be diagnosed by a qualified physician based on the overall clinical condition. However, based o...

[Read More] Understanding Chronic Eczema: Treatment, Management, and Concerns


Could Your Symptoms Indicate Ankylosing Spondylitis?

What is the likelihood of ankylosing spondylitis? Hello, Doctor Gao. At the beginning of April this year, I woke up one day with pain and stiffness in my shoulders and neck, making it almost impossible to turn my head normally. This lasted for more than a week, but then it gradua...


Dr. Gao Jiankai Reply:
Hello, thank you for your question. Based on your symptoms, the likelihood of you having ankylosing spondylitis is very low, so there is no need to worry; I believe your travel plans should not be affected. However, the issue of night sweats and fever still needs to be addressed....

[Read More] Could Your Symptoms Indicate Ankylosing Spondylitis?


Understanding the Link Between High Uric Acid and Heart Health

Cardiac issues and elevated uric acid levels? Cardiac issues: I experience shortness of breath while jogging, which prevents me from continuing. This phenomenon occurs about 10 minutes into jogging (I haven't recorded it carefully). Which department should I visit for an exa...


Dr. Gao Jiankai Reply:
Hello, thank you for your question. Indeed, there is a trend of metabolic diseases occurring at younger ages, and it's great that you are being vigilant. Regarding your concerns, my recommendations are as follows: 1. If you experience shortness of breath during jogging, it...

[Read More] Understanding the Link Between High Uric Acid and Heart Health


Understanding Blood Test Results: Assessing Chest Pain and Heart Attack Risk

Symbolic significance of specimens 1. The laboratory results you provided show the following values: - White blood cell count: 10,000 cells/µL (normal range is typically 4,000 to 11,000 cells/µL) - Neutrophils: 76.1% (normal range is usually around 40-70%) - Lymphocytes: 15.3% ...


Dr. Zeng Guosen Reply:
Hello, the only test result showing is a slightly elevated CRP at 0.8 (normal <0.5), while all other results are normal. Based on your tests and symptoms, a diagnosis of myocardial infarction cannot be made. If you have concerns, it is recommended that you consult a cardiologi...

[Read More] Understanding Blood Test Results: Assessing Chest Pain and Heart Attack Risk


Understanding Diabetes Risk: Interpreting Your Blood Test Results

What is the likelihood of developing diabetes? Hello Doctor, Happy New Year! I would like to ask about my fasting blood test results after 12 hours: Mean Corpuscular Volume (MCV) 78.5, Hemoglobin 24.6, High-Sensitivity C-Reactive Protein (hs-CRP) 10.58, Glycated Hemoglobin (HbA1c...


Dr. Xiao Yongxun Reply:
1. Your fasting blood test report shows an average red blood cell volume of 78.5, hemoglobin of 24.6, high-sensitivity C-reactive protein of 10.58, glycated hemoglobin (HbA1c) of 7.7, GOT (AST) of 86, GPT (ALT) of 172, alkaline phosphatase of 110, total iron binding capacity of 5...

[Read More] Understanding Diabetes Risk: Interpreting Your Blood Test Results


Understanding Cellulitis: A Patient's 21-Day Struggle with Infection

Cellulitis, hospitalized for 11 days... on the 21st day... still suffering? Dear Dr. Liao, The patient does not have liver disease or diabetes and has sinusitis. The bacteria causing the infection and the substances they have been exposed to cannot be determined. The patient is ...


Dr. Liao Zhongxin Reply:
Dear readers: 1. If the knee is still swollen and round, rehabilitation exercises can be performed at the bedside or on a chair to improve circulation and reduce edema. 2. The goal is to keep the C-reactive protein (CRP) level below 1. Sometimes it may take a bit longer to gra...

[Read More] Understanding Cellulitis: A Patient's 21-Day Struggle with Infection


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