Can Missing Birth Control Pills and Taking Amoxicillin Lead to Pregnancy? - Obstetrics and Gynecology

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I would like to ask about missing a dose of birth control pills and then taking one 500mg tablet of Amoxicillin on the same day?


Hello Doctor, I would like to ask about an issue with missing a dose of my oral contraceptive.
My last menstrual period started on February 28.
I took my medication at 11 PM on March 17, and I had sexual intercourse with my boyfriend on March 18.
I forgot to take the pill on March 19, and on that day, I also took Amoxicillin.
I took two pills to catch up on March 20.
Is there a chance of pregnancy in this situation? I understand that Amoxicillin may interact with the contraceptive pills.
I had already completed one pack before this month, and this is my second pack.
Thank you, Doctor.
Additionally, the doctor I consulted previously mentioned that I have a progesterone deficiency and need to receive regular injections at the hospital.

Niming, 20~29 year old female. Ask Date: 2016/03/22

Dr. Zhang Kunmin reply Obstetrics and Gynecology


What you need is not medical consultation but rather a refresher on sexual health knowledge.
For such inquiries, it is recommended to refer to the National Health Administration's "Sexual Happiness e-Learning" or the Obstetrics and Gynecology Society's "Consultation Guide for Adolescent Contraception" at http://goo.gl/dc6PfW.

Hello, the inquirer: Some medications can indeed affect the efficacy of contraceptives, including certain antibiotics, enzyme inducers, and some HIV treatment medications.
Among these, cold medications often contain antibiotics.
Therefore, if you need to take any of the aforementioned medications while on birth control, it is advisable to use additional contraceptive measures for seven days.
It is recommended that you consult with an obstetrician-gynecologist for evaluation.
Thank you! Wishing you safety and health, Dr.
Zhang.

Reply Date: 2016/03/22

More Info


Missing birth control pills can indeed increase the risk of unintended pregnancy, especially when combined with other factors such as taking antibiotics like Amoxicillin. Let’s break down the situation you described to better understand the implications.

1. Effectiveness of Birth Control Pills: Birth control pills are designed to prevent ovulation and thus reduce the chances of pregnancy. However, their effectiveness can be compromised if pills are missed. If you missed a pill on March 19 and had unprotected intercourse on March 18, there is a possibility that ovulation could have occurred, especially if you were nearing the end of your pill pack. The effectiveness of the pill decreases significantly with missed doses, particularly if you miss a pill during the first week of a new pack.

2. Interaction with Amoxicillin: While it was once believed that antibiotics like Amoxicillin could interfere with the effectiveness of birth control pills, recent studies suggest that this interaction is not significant for most antibiotics. However, some antibiotics can affect the gut flora, which may impact the absorption of the hormones in the birth control pills. Since you took Amoxicillin on March 19, the timing of your missed pill and the antibiotic could potentially contribute to a higher risk of pregnancy, although the risk may not be as high as once thought.

3. Timing and Hormonal Levels: Given that you have a history of progesterone deficiency (as indicated by your need for regular injections), your hormonal balance may already be delicate. Missing a pill could further disrupt your hormonal levels, potentially leading to ovulation. If you are not consistently taking your birth control as prescribed, this could increase your risk of pregnancy.

4. What to Do Next: If you are concerned about the possibility of pregnancy, consider taking a home pregnancy test if your period is late. Pregnancy tests are most accurate when taken after a missed period. Additionally, if you are experiencing any unusual symptoms or have concerns about your hormonal health, it would be wise to consult your healthcare provider for further evaluation and guidance.

5. Preventive Measures: To avoid similar situations in the future, consider setting reminders for taking your birth control pills or discussing alternative contraceptive methods with your healthcare provider. If you frequently miss pills, it might be worth exploring long-acting reversible contraceptives (LARCs) such as IUDs or implants, which do not require daily attention.

In summary, while missing birth control pills and taking Amoxicillin can increase the risk of pregnancy, the actual likelihood depends on various factors, including the timing of your missed pill, your menstrual cycle, and your individual hormonal health. If you have ongoing concerns about your reproductive health or contraceptive methods, it’s essential to have an open dialogue with your healthcare provider. They can provide personalized advice based on your medical history and current situation.

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I'm sorry, but I can't assist with that.


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