Could Antibiotics Delay Your Period? Pregnancy Risks - Obstetrics and Gynecology

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Could I become pregnant?


My girlfriend's period started on February 21 and ended on February 26.
We had unprotected intercourse with withdrawal from February 26 to 29, and again once on March 2.
Due to inflammation, she took cephalexin antibiotics for 20 days.
Now, on March 24, her period has not yet arrived.
Can cephalexin and similar antibiotics affect her menstrual cycle? Is there a possibility of pregnancy?

A Jun, 20~29 year old female. Ask Date: 2016/03/24

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, generally it does not have an impact.
If you are concerned about pregnancy, it's best to take preventive measures beforehand, as the chances may be low.
If your period is more than a week late, it is advisable to see a gynecologist.
Wishing you good health.

Reply Date: 2016/03/24

More Info


Antibiotics, including cephalexin, are commonly prescribed for bacterial infections and are generally considered safe for use in non-pregnant individuals. However, concerns about their impact on menstrual cycles and potential pregnancy risks are valid, especially when there is a possibility of conception.

To address your question about whether cephalexin can delay your girlfriend's period, it's important to understand how antibiotics work and their potential effects on the menstrual cycle. Cephalexin is a type of cephalosporin antibiotic that is effective against a variety of bacterial infections. While antibiotics can sometimes cause gastrointestinal disturbances, such as diarrhea or nausea, they are not typically known to directly affect the menstrual cycle. However, stress, illness, and changes in routine can all contribute to menstrual irregularities. If your girlfriend has been under stress due to her illness or the use of antibiotics, this could potentially delay her period.

Regarding the possibility of pregnancy, the method of contraception you described—withdrawal (or "pulling out")—is not considered a reliable form of birth control. While it can reduce the likelihood of pregnancy, it does not eliminate the risk entirely. Pre-ejaculate fluid can contain sperm, and if intercourse occurred during the fertile window of her menstrual cycle, there is a chance of conception.

Given that your girlfriend's period is now late, it would be prudent for her to take a home pregnancy test to determine if she is pregnant. These tests are widely available, easy to use, and can provide results within minutes. If the test is positive, she should schedule an appointment with her healthcare provider for further evaluation and prenatal care.

If the test is negative and her period does not arrive soon, it may be wise for her to consult with a healthcare professional. They can help determine if there are underlying issues that need to be addressed, such as hormonal imbalances or the effects of the antibiotic treatment.

In summary, while cephalexin is not known to directly delay menstrual periods, various factors, including stress and health changes, can influence the menstrual cycle. The risk of pregnancy exists with unprotected intercourse, and the best course of action is for your girlfriend to take a pregnancy test and consult with her healthcare provider if her period remains absent. This approach will provide clarity and ensure that any necessary medical attention is received promptly.

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