Antibiotics and Emergency Contraception: Pregnancy Risks Explained - Obstetrics and Gynecology

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Drug interactions. Emergency contraceptive pills. Issues with contraceptive pills?


Hello Doctor, I have been undergoing treatment with "Doxycycline" for an inflammation issue.
I had sexual intercourse on October 28 (without ejaculation), and the man's condition was variable that day.
I also had sexual intercourse on November 7 and November 12 (without ejaculation).
After the intercourse on November 7, I took an emergency contraceptive pill on November 8.
My menstrual period was originally expected to start on November 9, but as of today, November 12, I have not experienced any bleeding or menstruation.
I read online that taking antibiotics can delay the menstrual cycle, but it can also reduce the effectiveness of emergency contraceptive pills.
I would like to ask the doctor if there is a possibility that I could be pregnant.

B, 20~29 year old female. Ask Date: 2022/11/12

Dr. Lin Lixuan reply Obstetrics and Gynecology


Hello: Even with the consistent use of condoms during sexual intercourse, there is still about a 1% chance of pregnancy.
There are many types of antibiotics, and not all of them cause menstrual irregularities.
It is necessary to assess whether there are other factors affecting the menstrual cycle (such as incomplete treatment of infections, physical stress leading to delayed menstruation, pregnancy, etc.).
If there are irregularities in the menstrual cycle, a prolonged absence of menstruation, or abnormal bleeding (such as brown discharge), it is recommended to visit a nearby obstetrics and gynecology clinic for further evaluation, including ultrasound and pregnancy tests.

Reply Date: 2022/11/12

More Info


When it comes to the use of antibiotics and emergency contraception, particularly in the context of pregnancy, there are several important factors to consider. Your situation involves the use of an antibiotic called "Doxycycline" (assuming this is what you meant by "雙合黴素膜衣錠"), and the use of emergency contraception after unprotected intercourse.
First, let's clarify the role of antibiotics in relation to menstrual cycles and pregnancy. Generally, antibiotics do not directly affect the menstrual cycle. However, certain antibiotics can interact with hormonal contraceptives, potentially reducing their effectiveness. Doxycycline, for example, is not known to significantly interfere with the effectiveness of emergency contraceptive pills (ECPs) like Plan B or Ella. Therefore, if you took the ECP after unprotected intercourse, it should still be effective in preventing pregnancy, regardless of your antibiotic use.

Regarding your missed period, there are several reasons why your menstrual cycle might be delayed. Stress, changes in weight, illness, and hormonal fluctuations can all contribute to a delay in menstruation. Since you mentioned that your period was expected on November 9 and you have not yet experienced any bleeding, it is understandable to be concerned about the possibility of pregnancy. However, the fact that you took emergency contraception shortly after unprotected intercourse is a positive factor in reducing that risk.

It's also important to note that the timing of your menstrual cycle can vary, and it is not uncommon for periods to be late occasionally. If you are experiencing other symptoms of pregnancy, such as nausea, breast tenderness, or fatigue, it may be worth taking a home pregnancy test for confirmation. These tests are generally reliable and can provide you with peace of mind.

In summary, while antibiotics can sometimes complicate the effectiveness of certain medications, Doxycycline is not known to significantly impact the efficacy of emergency contraception. Your missed period could be due to a variety of factors unrelated to pregnancy. If you remain concerned or if your period does not arrive soon, consider consulting with a healthcare provider for further evaluation and guidance. They can provide you with more personalized advice and may suggest a blood test to determine if you are pregnant.

In conclusion, while the use of antibiotics and emergency contraception can raise questions about pregnancy risks, it is essential to consider the specific medications involved and their interactions. If you have any further concerns or questions, do not hesitate to reach out to your healthcare provider for assistance. They can help you navigate this situation and ensure your health and well-being.

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