Eustachian tube dysfunction: Issues with pharmacological treatment?
Hello Doctor, I previously inquired about issues related to the inner ear, and I later visited an otolaryngologist for an examination.
I underwent a hearing test which came back normal, and there was no fluid accumulation in the inner ear.
The doctor mentioned that the diagnosis should remain the same, indicating vestibular dysfunction.
I would like to ask if long-term use of Betahistine could lead to other side effects, such as elevated liver function tests or other bodily indices? Additionally, I would like to inquire about the long-term use of intranasal corticosteroids like Fluticasone.
Could they cause side effects such as moon facies or buffalo hump, which are common steroid-related side effects? Lastly, if vestibular dysfunction is left untreated, could it lead to hearing loss or deafness? Thank you very much for your careful reading and answers to these questions.
CHE, 20~29 year old female. Ask Date: 2016/04/25
Dr. Zheng Jueyi reply Otolaryngology
Hello: Most patients taking Montelukast do not experience any impact on liver function, except for a few individuals with impaired kidney function who may require dosage adjustments; it is generally considered quite safe.
As for intranasal corticosteroid sprays, prolonged use does not lead to the common side effects associated with oral corticosteroids, due to the extremely low absorption rate in the body.
Whether Eustachian tube dysfunction causes changes in hearing is related to the severity of the condition; in severe cases, it may lead to hearing deterioration due to fluid accumulation or tympanic membrane retraction.
Wishing you peace and health.
Sincerely, Dr.
Jue-Yi Cheng, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.
Reply Date: 2016/04/25
More Info
Understanding ear dysfunction, particularly in the context of medication effects and potential risks, is crucial for managing symptoms and ensuring overall health. Ear dysfunction can manifest in various forms, including tinnitus (ringing in the ears), hearing loss, and eustachian tube dysfunction, which can lead to feelings of fullness or pressure in the ears.
Regarding your inquiry about the medication "Dexamethasone" (often referred to as "驅異樂" in Chinese), it is a corticosteroid that is commonly used to reduce inflammation and treat various conditions, including those affecting the ear, nose, and throat. Long-term use of corticosteroids can lead to several side effects, but the risk of systemic effects, such as elevated liver function tests or other bodily indices, is generally low when using nasal sprays or localized treatments. This is because the absorption of these medications into the bloodstream is minimal compared to oral corticosteroids.
However, it is important to monitor for potential side effects, especially if the medication is used for an extended period. Common side effects of systemic corticosteroids include weight gain, mood changes, and increased blood sugar levels, but these are less likely with nasal sprays. The specific side effects you mentioned, such as "moon face" and "buffalo hump," are typically associated with long-term oral corticosteroid use rather than localized treatments.
As for your question about the eustachian tube dysfunction and its potential consequences if left untreated, it is indeed possible for untreated eustachian tube dysfunction to lead to complications. Chronic dysfunction can result in fluid accumulation in the middle ear, which may lead to conductive hearing loss. In severe cases, persistent fluid can cause infections or even lead to more serious conditions such as tympanic membrane perforation or chronic otitis media. Therefore, it is advisable to address eustachian tube dysfunction promptly to prevent these complications.
In summary, while medications like Dexamethasone can be effective in managing ear-related issues, it is essential to use them under the guidance of a healthcare professional. Regular follow-ups and monitoring for side effects are crucial, especially if you have underlying conditions or are taking multiple medications. If you experience any unusual symptoms or side effects, it is important to consult your healthcare provider for further evaluation and management.
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