Persistent Abnormal Pap Smear After Laser Treatment: What to Do Next? - Obstetrics and Gynecology

Share to:

After undergoing laser treatment for cervical cell lesions, the follow-up Pap smear still shows abnormalities!


Hello Doctor, three months ago I had a Pap smear that showed mild epithelial cell dysplasia.
After undergoing a large excisional biopsy to remove the abnormal area, I returned for a follow-up Pap smear two days ago, and the results are still abnormal...
Could you please explain this situation? Is it possible that the previous surgery did not completely remove the abnormal cells? Additionally, I just received my third dose of the HPV vaccine on May 25.
Could this affect the Pap smear results? Is it common for the Pap smear to still be abnormal after a large excisional biopsy? This is really concerning for me...
Do I need to undergo another surgery? Thank you!

Xiao Ai, 40~49 year old female. Ask Date: 2016/06/25

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, if there is mild epithelial cell dysplasia, it is recommended to follow up in three months.
If abnormalities persist, a larger biopsy can be performed.
The HPV vaccine does not affect the results of the Pap smear report.
Wishing you good health.

Reply Date: 2016/06/25

More Info


Persistent abnormal Pap smear results after laser treatment can be concerning and understandably distressing. It’s essential to approach this situation with a clear understanding of what might be happening and the steps you can take moving forward.

Firstly, it’s important to recognize that an abnormal Pap smear can result from various factors, including residual abnormal cells that were not completely removed during the previous procedure. In your case, since you underwent a large excisional biopsy (often referred to as a LEEP or Loop Electrosurgical Excision Procedure), it is possible that some abnormal cells were left behind, leading to the persistent abnormal results. This is not uncommon, and it can happen for several reasons, including the extent of the abnormality and the precision of the excision.

Regarding your recent HPV vaccination, it’s important to note that while the HPV vaccine is effective in preventing certain strains of the virus that can lead to cervical cancer, it does not affect the results of a Pap smear in the short term. The vaccine works by helping your body build immunity to the virus, but it does not eliminate existing infections or abnormal cells that may already be present. Therefore, the timing of your vaccination in relation to your Pap smear results is unlikely to be a contributing factor to the abnormal findings.

It’s also worth mentioning that persistent abnormal Pap results after treatment can occur. In some cases, the abnormal cells may take time to resolve, or there may be a need for further intervention if the abnormality persists. The follow-up protocol typically involves close monitoring, which may include repeat Pap smears and possibly HPV testing to assess the situation further.

Given your circumstances, here are some steps you might consider:
1. Consult Your Gynecologist: Schedule an appointment with your gynecologist to discuss your concerns in detail. They can provide clarity on the results and the next steps based on your specific situation.

2. Further Testing: Your doctor may recommend additional testing, such as a colposcopy, which allows for a closer examination of the cervix and can help identify any areas of concern that may need to be biopsied.

3. Consideration of Further Treatment: If the abnormal cells are confirmed to be persistent and concerning, your doctor may discuss the possibility of further treatment options. This could include another excisional procedure or other methods to ensure that any remaining abnormal cells are adequately addressed.

4. Regular Monitoring: If immediate further treatment is not necessary, your doctor may recommend a schedule for regular monitoring through Pap smears and HPV testing to track any changes over time.

5. Emotional Support: It’s completely normal to feel anxious or worried about your health in this situation. Consider seeking support from friends, family, or even professional counseling if you find the stress overwhelming.

In summary, while persistent abnormal Pap smear results can be concerning, they are not uncommon after treatment. The best course of action is to maintain open communication with your healthcare provider, follow their recommendations for further testing or treatment, and ensure that you are monitored closely. Remember, early detection and intervention are key in managing cervical health effectively.

Similar Q&A

Effective Treatments and Prevention Strategies for Post-Laser Spotting

Hello! I would like to ask what additional treatments can be done if mild localized spots reappear after laser spot removal? Or how can I prevent post-inflammatory hyperpigmentation to be more effective than treatment? Thank you!


Dr. Hong Zhengsheng reply Dermatology
Hello Ting: After undergoing laser spot removal, post-operative sun protection and skincare are very important. I recommend that you return to the physician who performed the laser treatment to consult with them on the best post-operative care for your current skin condition. Tha...

[Read More] Effective Treatments and Prevention Strategies for Post-Laser Spotting


Understanding Laser Spot Removal: Risks, Results, and Aftercare

Hello, doctor. I previously went to a regional hospital for laser spot removal. The procedure involved treating each spot with a single pulse, which felt like being flicked with a rubber band. After the treatment, the spots temporarily enlarged and then formed scabs that fell off...


Dr. Huang Ruiyun reply Dermatology
There are many types of lasers, each with different indications, as well as some overlapping similarities. It is crucial to have an accurate diagnosis, select the appropriate device, and perform the procedure correctly. If your spots are superficial, there are quite a few options...

[Read More] Understanding Laser Spot Removal: Risks, Results, and Aftercare


Post-Retinal Laser Treatment Care: Essential Tips and Common Concerns

Hello, Doctor. I underwent retinal laser treatment on both eyes at the end of January and returned for a follow-up in late February. The doctor informed me that the treated areas were stable, which relieved my anxiety. The doctor also specifically instructed me to return for an e...


Dr. Gao Pilin reply Ophthalmology
Hello: 1. The formation of retinal tears is usually caused by uneven traction within the eye, with the most common reason being vitreous contraction and thickening of the retinal membrane due to aging. Other causes may include external trauma or impact to the eye, ocular diseases...

[Read More] Post-Retinal Laser Treatment Care: Essential Tips and Common Concerns


Can Retinal Tears Reoccur After Laser Treatment? Understanding Your Eye Health

Hello, I am highly myopic with a prescription of approximately -1000 diopters. I undergo a fundus examination every six months to monitor the condition of my retina. During my routine examination six months ago, the clinic physician informed me that there was a tear in my right r...


Dr. Zhang Zhengzhong reply Ophthalmology
Hello Vicky, First, I would like to apologize for the delay due to Director Chang's busy schedule. I will address your concerns here: For patients with high myopia, regular retinal examinations are essential, and you are doing well in this regard. According to your descri...

[Read More] Can Retinal Tears Reoccur After Laser Treatment? Understanding Your Eye Health


Related FAQ

Pap Smear

(Obstetrics and Gynecology)

Cervical Intraepithelial Neoplasia

(Obstetrics and Gynecology)

Post-Hysteroscopy

(Obstetrics and Gynecology)

Human Papillomavirus

(Obstetrics and Gynecology)

Hpv Test

(Obstetrics and Gynecology)

Post-Coital Bleeding

(Obstetrics and Gynecology)

Vulva

(Obstetrics and Gynecology)

After Uterine Fibroid Surgery

(Obstetrics and Gynecology)

Genital Warts

(Obstetrics and Gynecology)

Endometrial Abnormalities

(Obstetrics and Gynecology)