After undergoing laser treatment for cervical cell lesions, the follow-up Pap smear still shows abnormalities!
Hello Doctor, three months ago I had a Pap smear that showed mild epithelial cell dysplasia.
After undergoing a large excisional biopsy to remove the abnormal area, I returned for a follow-up Pap smear two days ago, and the results are still abnormal...
Could you please explain this situation? Is it possible that the previous surgery did not completely remove the abnormal cells? Additionally, I just received my third dose of the HPV vaccine on May 25.
Could this affect the Pap smear results? Is it common for the Pap smear to still be abnormal after a large excisional biopsy? This is really concerning for me...
Do I need to undergo another surgery? Thank you!
Xiao Ai, 40~49 year old female. Ask Date: 2016/06/25
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, if there is mild epithelial cell dysplasia, it is recommended to follow up in three months.
If abnormalities persist, a larger biopsy can be performed.
The HPV vaccine does not affect the results of the Pap smear report.
Wishing you good health.
Reply Date: 2016/06/25
More Info
Persistent abnormal Pap smear results after laser treatment can be concerning and understandably distressing. It’s essential to approach this situation with a clear understanding of what might be happening and the steps you can take moving forward.
Firstly, it’s important to recognize that an abnormal Pap smear can result from various factors, including residual abnormal cells that were not completely removed during the previous procedure. In your case, since you underwent a large excisional biopsy (often referred to as a LEEP or Loop Electrosurgical Excision Procedure), it is possible that some abnormal cells were left behind, leading to the persistent abnormal results. This is not uncommon, and it can happen for several reasons, including the extent of the abnormality and the precision of the excision.
Regarding your recent HPV vaccination, it’s important to note that while the HPV vaccine is effective in preventing certain strains of the virus that can lead to cervical cancer, it does not affect the results of a Pap smear in the short term. The vaccine works by helping your body build immunity to the virus, but it does not eliminate existing infections or abnormal cells that may already be present. Therefore, the timing of your vaccination in relation to your Pap smear results is unlikely to be a contributing factor to the abnormal findings.
It’s also worth mentioning that persistent abnormal Pap results after treatment can occur. In some cases, the abnormal cells may take time to resolve, or there may be a need for further intervention if the abnormality persists. The follow-up protocol typically involves close monitoring, which may include repeat Pap smears and possibly HPV testing to assess the situation further.
Given your circumstances, here are some steps you might consider:
1. Consult Your Gynecologist: Schedule an appointment with your gynecologist to discuss your concerns in detail. They can provide clarity on the results and the next steps based on your specific situation.
2. Further Testing: Your doctor may recommend additional testing, such as a colposcopy, which allows for a closer examination of the cervix and can help identify any areas of concern that may need to be biopsied.
3. Consideration of Further Treatment: If the abnormal cells are confirmed to be persistent and concerning, your doctor may discuss the possibility of further treatment options. This could include another excisional procedure or other methods to ensure that any remaining abnormal cells are adequately addressed.
4. Regular Monitoring: If immediate further treatment is not necessary, your doctor may recommend a schedule for regular monitoring through Pap smears and HPV testing to track any changes over time.
5. Emotional Support: It’s completely normal to feel anxious or worried about your health in this situation. Consider seeking support from friends, family, or even professional counseling if you find the stress overwhelming.
In summary, while persistent abnormal Pap smear results can be concerning, they are not uncommon after treatment. The best course of action is to maintain open communication with your healthcare provider, follow their recommendations for further testing or treatment, and ensure that you are monitored closely. Remember, early detection and intervention are key in managing cervical health effectively.
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