Sleep Issues: Medication and Neurological Insights - Psychiatry

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Medication Consultation: Insomnia


Hello Doctor, I have a question about my insomnia.
I visited a neurologist, and I asked why I keep wanting to sleep.
When I am in deep sleep, my body often jerks, which makes it hard for me to fall back asleep.
I would like to ask if this could be related to the fact that since last month, I have been taking my evening medication, Clonazepam 0.5 mg, and I split one tablet into four parts.
Now, I take a little bit before I sleep.
I understand that Clonazepam 0.5 mg is an anticonvulsant medication.

Here are the medications prescribed by the neurologist: Currently, I am only taking Clonazepam 0.5 mg; I am not taking the others because I want to see if I can sleep without medication.
After breakfast, I take: 1.
Methylcobalamin 0.5 mg (B12) - I switched to this medication in February.
2.
Seroquel 0.25 mg - I take this before sleeping.
3.
Clonazepam 0.5 mg - I switched to this medication in February; previously, I was taking Lorazepam 0.5 mg.
4.
Calcium Carbonate 500 mg.
5.
A dietary supplement called Sinopine (out-of-pocket expense).

Cai Xiansheng, 30~39 year old female. Ask Date: 2016/07/12

Dr. Wang Zhenbang reply Psychiatry


Hello Mr.
Tsai, if you have already visited a clinic to see a physician, I recommend that you ask your doctor directly about any medication-related questions for more accurate information.
Regarding the medication Clonazepam that you mentioned, it is a type of sedative-hypnotic drug primarily used for its anxiolytic effects, muscle relaxation, and sleep aid properties.
It is widely used, including for the treatment of epilepsy, but treating epilepsy is not its only indication.
Given the dosage you are currently using, the likelihood of experiencing significant side effects is low; however, individual responses can vary based on personal health conditions and circumstances.
It is still advisable to have a thorough discussion with your clinic physician.
Wishing you health and safety, Dr.
Wang Zhengbang.

Reply Date: 2016/07/12

More Info


Sleep disturbances can be a complex issue, often influenced by a variety of factors including medication, neurological conditions, and psychological stress. In your case, it seems that you are experiencing a combination of insomnia and involuntary muscle jerks during sleep, which can be quite distressing.

Firstly, let's address the medication you mentioned, specifically the use of Lamotrigine (景德克癇平錠). This medication is primarily used to treat epilepsy and bipolar disorder. While it can be effective for these conditions, it may also have side effects that impact sleep. Some individuals report experiencing sleep disturbances, including insomnia or unusual movements during sleep, which could manifest as the jerking you described. This phenomenon is often referred to as myoclonic jerks, which are sudden, involuntary muscle contractions that can occur as one is falling asleep or during sleep.
The fact that you have been adjusting your dosage by splitting the 0.5 mg tablet into four parts may also play a role in your sleep quality. It's essential to follow your doctor's guidance regarding medication adjustments, as improper dosing can lead to fluctuations in drug levels in your system, potentially exacerbating side effects. If you are experiencing increased muscle jerks or other sleep disturbances after changing your dosage, it would be wise to discuss this with your neurologist. They may need to reassess your treatment plan or consider alternative medications that might have a more favorable side effect profile regarding sleep.

Additionally, you mentioned taking other medications, such as Mecobalamin (甲鈷胺明) and Seroquel (生達"癒利舒盼錠). Mecobalamin is a form of vitamin B12 that is often used to treat neuropathy and may not directly affect sleep. However, Seroquel, an atypical antipsychotic, is sometimes prescribed off-label for insomnia due to its sedative properties. If you are taking multiple medications, it is crucial to consider potential interactions and cumulative effects on your sleep.
Moreover, the psychological aspect of your sleep issues cannot be overlooked. Anxiety and stress can significantly impact sleep quality. If you find yourself worrying about your sleep or the effects of your medications, this anxiety can create a vicious cycle, making it even harder to fall asleep. Techniques such as cognitive-behavioral therapy for insomnia (CBT-I) can be beneficial in addressing these concerns. This therapy focuses on changing the thoughts and behaviors that contribute to sleep problems.

In terms of lifestyle modifications, consider establishing a consistent sleep schedule, creating a relaxing bedtime routine, and ensuring your sleep environment is conducive to rest (dark, quiet, and cool). Avoiding stimulants such as caffeine and nicotine, especially in the hours leading up to bedtime, can also help improve sleep quality.

Lastly, it is essential to communicate openly with your healthcare provider about your sleep issues and any side effects you are experiencing from your medications. They can help you navigate these challenges and may suggest alternative treatments or therapies to improve your sleep without relying solely on medication.

In summary, your sleep disturbances may be influenced by the medications you are taking, as well as psychological factors. It is crucial to work closely with your healthcare provider to find a balanced approach that addresses both your neurological condition and your sleep issues.

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