Using Ofloxacin Ear Drops: What to Do After Missing Doses? - Otolaryngology

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I am currently using Tobramycin ear drops?


I have been using Ofloxacin ear drops for one day, twice a day, but I forgot to bring the medication when I went out and didn’t return for about a week.
After using the drops for one day, I didn’t use them for 5 to 6 days.
Should I continue using the drops for 6 more days to complete the 7-day treatment, or is it too late and have I developed antibiotic resistance? Additionally, is it normal to experience itching and pain after applying the drops? Could this be related to the treatment of otitis externa?

Yīshī nǐ hǎo, 20~29 year old female. Ask Date: 2016/07/20

Dr. Zheng Jueyi reply Otolaryngology


Hello, if you are still experiencing discomfort in your ear, it is recommended to continue using the drops and return for a follow-up examination after one week.
Occasional sharp pain can be a normal reaction, but if the discomfort persists, it is advisable to schedule an earlier appointment for evaluation.
Wishing you safety and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2016/07/20

More Info


When it comes to using Ofloxacin ear drops, missing doses can be a concern, especially if you have been prescribed a specific treatment regimen. In your case, you mentioned that you used the drops for one day (two times) and then missed approximately five to six days before returning home and resuming treatment. Here’s how to approach this situation:
1. Resuming Treatment: It is generally advisable to continue the course of treatment as prescribed by your healthcare provider, even after missing doses. Since you have missed several days, you should ideally consult your doctor or pharmacist for specific guidance tailored to your situation. However, if you are feeling discomfort or pain, it may be beneficial to resume the drops as soon as possible. Continuing the treatment for the remaining days (in your case, six more days) can help ensure that the infection is adequately treated.

2. Concerns About Resistance: The concern about developing antibiotic resistance typically arises when antibiotics are not taken as prescribed or when they are used improperly. Since Ofloxacin is an antibiotic, missing doses could theoretically lead to insufficient treatment of the infection, which might contribute to resistance. However, if you resume the treatment promptly and complete the course, it is unlikely that you will develop resistance simply due to the missed doses. The key is to follow through with the remaining doses as directed.

3. Side Effects and Symptoms: It is not uncommon to experience some itching or a slight stinging sensation after applying ear drops like Ofloxacin. This can be a normal reaction as the medication works to eliminate the bacteria causing the infection. However, if the itching or pain becomes severe or if you notice any unusual symptoms such as increased swelling, redness, or discharge, it is important to contact your healthcare provider. These could be signs of an adverse reaction or worsening of the condition.

4. Monitoring Your Condition: After resuming the drops, keep an eye on your symptoms. If you notice that your pain or discomfort persists or worsens, or if you have any concerns about the effectiveness of the treatment, it is crucial to follow up with your healthcare provider. They may want to reassess your condition and determine if a different treatment approach is necessary.

5. General Advice: Always follow the instructions provided by your healthcare provider regarding medication use. If you ever miss a dose, the general rule is to take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Never double up on doses to make up for a missed one.

In summary, it is advisable to continue using the Ofloxacin ear drops for the remaining days of your treatment, monitor your symptoms, and consult your healthcare provider if you have any concerns or experience significant side effects. This approach will help ensure that your ear infection is treated effectively while minimizing the risk of complications or resistance.

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