Does D-Mannose Affect Pregnancy? Its Use and Safety - Obstetrics and Gynecology

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Does D-Mannose affect childbirth?


Hello! I have been suffering from urethritis and vaginitis for several months.
After multiple visits to the doctor and hospitalization, it was confirmed that I have Escherichia coli, but they have not been able to help me.
I have taken too many antibiotics and developed resistance.
I found online that there is a medication (D-mannose) that is used to treat and prevent urethritis.
I bought three bottles, each containing 1500 mg, and I take three capsules three times a day.
I feel like I am improving a bit, but since I am not fully cured, I continue to take it.
One day, I discovered online that this medication is used for contraception! I was shocked because I am preparing to have a baby and do not want to prevent pregnancy.
Please answer the following questions for me...
Thank you.
1) Is D-mannose confirmed to be a contraceptive?
2) Can this medication be taken long-term? Are there any side effects?
3) What impact will long-term urethritis and vaginitis have on my baby if I become pregnant? Thank you.

Hui Er, 30~39 year old female. Ask Date: 2016/08/02

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, D-mannose is just a type of sugar and should not have any contraceptive effects.
It is unlikely to have any impact on the baby.
Wishing you good health.

Reply Date: 2016/08/02

More Info


D-Mannose is a naturally occurring sugar that is often used as a supplement to help prevent and treat urinary tract infections (UTIs), particularly those caused by E. coli bacteria. It works by preventing bacteria from adhering to the walls of the urinary tract, thereby helping to flush them out of the body. Given your situation, where you have been experiencing recurrent UTIs and have been prescribed D-Mannose, it's important to address your concerns regarding its safety during pregnancy.

1. Does D-Mannose act as a contraceptive?
D-Mannose is not classified as a contraceptive. There is no scientific evidence to suggest that D-Mannose has any contraceptive properties. Its primary use is for the prevention and treatment of urinary tract infections, and it does not interfere with hormonal pathways or reproductive functions in a way that would prevent pregnancy. Therefore, you can rest assured that taking D-Mannose will not prevent you from becoming pregnant.

2. Is it safe to take D-Mannose long-term?
D-Mannose is generally considered safe for most individuals when taken in appropriate doses. The typical dosage for preventing UTIs is around 500 mg to 1500 mg taken two to three times a day. However, long-term use should always be discussed with a healthcare provider, especially during pregnancy. While there are no significant side effects reported with D-Mannose, excessive consumption may lead to gastrointestinal discomfort, such as diarrhea or bloating. It’s crucial to monitor your body’s response and consult with your healthcare provider if you experience any adverse effects.

3. What are the implications of chronic UTIs and vaginal infections during pregnancy?
Chronic urinary tract infections and vaginal infections can pose risks during pregnancy. UTIs can lead to complications such as kidney infections, which can be serious for both the mother and the baby. Additionally, untreated infections can increase the risk of preterm labor and low birth weight. It is essential to manage these infections effectively. If you are experiencing recurrent infections, it is advisable to work closely with your healthcare provider to develop a comprehensive treatment plan. This may include lifestyle modifications, dietary changes, and possibly the use of preventive antibiotics if necessary.

In summary, D-Mannose is not a contraceptive and is generally safe for use during pregnancy, but you should consult with your healthcare provider regarding long-term use and any potential side effects. Managing your recurrent UTIs and vaginal infections is crucial for your health and the health of your baby. Regular prenatal care and open communication with your healthcare team will help ensure a healthy pregnancy. If you have any further questions or concerns, do not hesitate to reach out to your healthcare provider for personalized advice.

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