Right Upper Abdominal Pain and Its Causes - Gastroenterology and Hepatology

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Right upper quadrant pain radiating to the back?


Hello, I have had my gallbladder removed.
Last year, I experienced mild pain in my lower right rib, and after an ultrasound, the doctor found stones in the bile duct, which led to an ERCP that caused pancreatitis.
Recently, the pain in my lower right rib has returned, radiating to my right back.
I experience daily bloating, poor appetite, occasional oily stools, and nausea.
My urine is tea-colored.
I went to the hospital for tests, and my blood tests for CA 19-9, Amylase, Lipase, bilirubin, and IgG all came back normal.
An MRI showed that the tail of my pancreas is enlarged.
The doctor suggested monitoring with follow-up blood tests and also recommended seeing an immunologist.
Given the persistent pain, could the enlarged tail of the pancreas be causing the pain, or could there be bile duct stones again? Should I consider a PET scan or other tests? I am hesitant to undergo ERCP again due to the risk of pancreatitis.
Additionally, I have had high urine ketones (with fat breakdown products in the urine) over the past year; could this indicate a pre-diabetic condition? I have many questions and would appreciate your response.
Thank you.

Ms. Chen, 20~29 year old female. Ask Date: 2016/08/16

Dr. Chen Qifeng reply Gastroenterology and Hepatology


1.
If there is enlargement of the pancreatic tail, it should cause pain in the left upper abdomen.

2.
There is a possibility of recurrence of bile duct stones, but blood tests are normal, which cannot explain the situation.

3.
A PET scan may not be very helpful.

4.
If ERCP is normal, then consideration should be given to performing an upper endoscopy.

5.
For diabetes, HbA1c or an oral glucose tolerance test should be evaluated.

Reply Date: 2016/08/16

More Info


Right upper abdominal pain can be a complex issue, especially considering your medical history, including gallbladder removal and a previous episode of pancreatitis. The symptoms you describe—pain radiating to the right back, bloating, poor appetite, occasional oily stools, nausea, and tea-colored urine—are concerning and warrant careful evaluation.


Possible Causes of Right Upper Abdominal Pain
1. Pancreatic Issues: Given that your MRI indicated an enlarged tail of the pancreas, this could be a significant factor in your pain. An enlarged pancreas can be indicative of pancreatitis or other pancreatic disorders, which can cause referred pain to the back and upper abdomen. Chronic pancreatitis can lead to pain, digestive issues, and even diabetes due to the pancreas's role in insulin production.

2. Biliary Tract Problems: Although you have had your gallbladder removed, it is still possible to have issues with the bile ducts. Bile duct stones (choledocholithiasis) can occur even after cholecystectomy, leading to pain and potential complications like cholangitis or pancreatitis. The fact that you have had stones in the past raises the suspicion that this could be a recurring issue.

3. Gastrointestinal Disorders: Conditions such as gastritis, peptic ulcers, or functional gastrointestinal disorders (like irritable bowel syndrome) can also manifest as upper abdominal pain. Given your symptoms of bloating and poor appetite, these should be considered.

4. Musculoskeletal Pain: Sometimes, pain in the upper abdomen can be due to musculoskeletal issues, especially if there is a history of injury or strain in that area. However, your symptoms seem more systemic than localized.

5. Diabetes Considerations: The mention of elevated urine ketones and concerns about prediabetes is important. If your body is not effectively utilizing glucose, it may be breaking down fat for energy, leading to ketone production. This metabolic state can cause abdominal discomfort and should be evaluated further.


Recommended Actions
1. Follow-Up with Your Healthcare Provider: Given the complexity of your symptoms and the potential for serious underlying conditions, it is crucial to maintain regular follow-ups with your healthcare provider. They can help monitor your pancreatic health and any changes in your symptoms.

2. Consider Additional Imaging: If your pain persists or worsens, further imaging studies such as a CT scan or a PET scan may provide more insight into the condition of your pancreas and surrounding structures. These tests can help identify any masses, inflammation, or other abnormalities that might not have been visible on the MRI.

3. Endoscopic Evaluation: While you are understandably hesitant about undergoing ERCP due to the risk of pancreatitis, it may still be a necessary procedure if there is a strong suspicion of bile duct stones or other obstructive processes. Discuss the risks and benefits with your doctor, and consider seeking a second opinion if you are uncertain.

4. Nutritional and Lifestyle Modifications: Given your symptoms of poor appetite and oily stools, it may be beneficial to consult with a dietitian who specializes in gastrointestinal health. They can help tailor a diet that minimizes discomfort and supports pancreatic function.

5. Monitor Blood Sugar Levels: If you suspect prediabetes, regular monitoring of your blood glucose levels is essential. Lifestyle changes, including diet and exercise, can significantly impact your metabolic health.


Conclusion
Your symptoms are multifaceted and could stem from various underlying issues, including pancreatic enlargement, biliary tract problems, or gastrointestinal disorders. It is essential to work closely with your healthcare team to monitor your condition and explore further diagnostic options. Keeping an open line of communication with your doctors will help ensure that you receive the appropriate care and interventions needed to manage your symptoms effectively.

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