Managing Medications for Ulcerative Colitis: Key Questions Answered - Gastroenterology and Hepatology

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Medications for Ulcerative Colitis


Hello Doctor: I have ulcerative colitis and have been taking Asacol 800mg, Xanax 0.25mg, Azamun 50mg, and Magnesium Oxide.
Occasionally, due to hyperthyroidism, I take Tapazole and Inderal, and sometimes I use dermatological medications such as Prednisolone, Strocaim, Zaditen, and Wanse.
The prescription indicates that all medications should be taken after meals.

Q1: How long should I wait between taking medications from different specialties or individual medications?
Q2: I have been experiencing severe hair loss recently; could this be due to taking too many medications at once? Thank you for taking the time to respond!

iris, 40~49 year old female. Ask Date: 2016/08/23

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, generally speaking, up to six medications can be taken at once, but it is still advisable to discuss this with the pharmacist at the prescribing hospital.
Changhua Hospital cares about your health.
Chen Shidian

Reply Date: 2016/08/23

More Info


Managing medications for conditions like ulcerative colitis can be complex, especially when multiple medications from different specialties are involved. Here, I will address your questions regarding the timing of medication administration and the potential side effects, such as hair loss.


Q1: How long should I wait between taking medications from different specialties?
When managing multiple medications, it is essential to consider potential interactions and the optimal absorption of each drug. Generally, it is advisable to space out medications to minimize any possible interactions and to enhance absorption. Here are some general guidelines:
1. Asacol (Mesalamine): This medication is used to treat ulcerative colitis and is best taken with food to enhance absorption. It is typically recommended to take it at the same time each day.

2. Xanax (Alprazolam): This medication is usually taken as needed for anxiety. If you are taking it regularly, it can be taken with or without food, but it is best to maintain a consistent routine.

3. Azamun (Azathioprine): This immunosuppressant is also best taken with food to reduce gastrointestinal side effects.
4. Magnesium Oxide: This supplement can interfere with the absorption of certain medications, particularly antibiotics. It is generally recommended to take it at least 2 hours apart from other medications.

5. Tapazole (Methimazole): This medication for hyperthyroidism can be taken with or without food, but consistency is key.

6. Inderal (Propranolol): This beta-blocker can be taken with or without food, but it is often recommended to take it consistently with meals.

7. Prednisolone: This corticosteroid should be taken with food to minimize gastrointestinal irritation.

8. Strocaim (likely a typo for a medication, please clarify), Zaditen (Ketotifen), and Wanse (likely a brand name for a medication): These medications should be taken as directed by your physician, and it is best to consult your doctor or pharmacist for specific instructions regarding timing and spacing.

In general, a good practice is to space medications by at least 1-2 hours when possible, especially when taking medications that may interact or affect absorption. Always consult with your healthcare provider for personalized advice based on your specific situation.


Q2: Could my recent hair loss be due to taking too many medications at once?
Hair loss can be a distressing side effect and can be attributed to various factors, including medications, stress, nutritional deficiencies, and underlying health conditions. In your case, several medications could potentially contribute to hair loss:
1. Azathioprine: This immunosuppressant can cause hair loss in some individuals.

2. Prednisolone: Long-term use of corticosteroids can also lead to hair thinning or loss.

3. Xanax: While not commonly associated with hair loss, anxiety and stress can contribute to hair shedding.

4. Tapazole: This medication can sometimes lead to hair loss as a side effect.

It is important to note that hair loss can also be a result of the underlying condition itself (in this case, ulcerative colitis) or due to stress related to managing a chronic illness. If you are experiencing significant hair loss, it is advisable to discuss this with your healthcare provider. They may recommend blood tests to check for deficiencies (like iron or thyroid function) or consider adjusting your medication regimen.


Conclusion
Managing multiple medications requires careful attention to timing and potential interactions. It is crucial to maintain open communication with your healthcare providers, who can help tailor your medication schedule and address any side effects you may be experiencing. If you have concerns about hair loss or any other side effects, do not hesitate to bring them up during your next appointment. Your health and well-being are paramount, and your healthcare team is there to support you in managing your conditions effectively.

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