Pros and Cons of Electroconvulsive Therapy for Schizophrenia - Psychiatry

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The advantages and disadvantages of electrotherapy?


Hello Doctor, I have been diagnosed with paranoid schizophrenia for 10 years.
For the past 4 years, I have been treated with Ziprasidone (5mg) and have not experienced any relapses.
However, due to the side effects of the medication, I am still unable to work in a regular workplace, so I am considering trying electroconvulsive therapy (ECT).
I understand that there is a risk of fractures associated with ECT.
If I undergo ECT once a week, totaling 50 sessions in a year, is it normal to expect at least a few fractures? I am capable of self-care in my daily life; I just cannot work in a regular job.
Would you still recommend ECT for me? Additionally, I take 5mg of Ziprasidone daily.
Is there a high risk of developing diabetes with long-term use of this medication? Thank you for your patience in reading my concerns.

Wu Mou, 20~29 year old female. Ask Date: 2016/10/28

Dr. Liang Sunyuan reply Psychiatry


Hello Mr.
Wu: Electroconvulsive therapy (ECT) in psychiatry is typically considered only when medication treatment is ineffective.
If oral medications can already control the symptoms, ECT is usually not pursued.
Additionally, ECT may have side effects such as short-term memory loss, which may not be very helpful in terms of employment.
A dosage of 5 mg of Ziprasidone is considered low, and the risk of developing diabetes should not be significantly high.
This risk can be managed through dietary control, regular exercise, and routine blood tests.
Wishing you all the best.

Reply Date: 2016/10/28

More Info


Electroconvulsive Therapy (ECT) is a treatment option that has been used for various psychiatric disorders, including schizophrenia, particularly in cases where other treatments have failed or when rapid response is necessary. However, like any medical intervention, it comes with its own set of pros and cons.


Pros of Electroconvulsive Therapy for Schizophrenia:
1. Rapid Relief of Symptoms: ECT can provide quick relief from severe symptoms of schizophrenia, especially in acute episodes where immediate intervention is necessary. This can be particularly beneficial for patients experiencing severe psychosis or suicidal ideation.

2. Effectiveness: Studies have shown that ECT can be effective for treatment-resistant schizophrenia. For some patients, it may lead to significant improvements in mood, thought processes, and overall functioning.

3. Alternative to Medication: For patients who cannot tolerate the side effects of antipsychotic medications or who have not responded to them, ECT can be a viable alternative. It may help reduce the reliance on medications that can have long-term side effects.

4. Improvement in Quality of Life: For some individuals, successful ECT treatment can lead to a marked improvement in their ability to function in daily life, potentially allowing them to return to work or engage in social activities.


Cons of Electroconvulsive Therapy for Schizophrenia:
1. Side Effects: ECT can cause side effects, including confusion, memory loss, and physical side effects such as headaches and muscle soreness. Memory loss can be particularly concerning, as it may affect the patient's ability to recall events before and after treatment.

2. Risk of Fractures: As you mentioned, there is a risk of fractures during ECT due to the muscle contractions that occur during the seizure. While this risk is generally low, it is a valid concern, especially if ECT is administered frequently.

3. Stigma and Acceptance: There can be a stigma associated with ECT, which may affect a patient's willingness to undergo the treatment. Additionally, some patients may feel anxious about the procedure itself.

4. Need for Anesthesia: ECT requires the use of anesthesia, which carries its own risks, particularly for individuals with certain medical conditions. This necessitates careful screening and monitoring.


Considerations for Your Situation:
Given your history of paranoid schizophrenia and the fact that you have been stable on medication for four years, the decision to pursue ECT should be made carefully. It is crucial to weigh the potential benefits against the risks, especially considering your concerns about bone fractures and the side effects of long-term medication use.

1. Consultation with a Specialist: It would be beneficial to discuss your specific case with a psychiatrist who specializes in ECT. They can provide insights tailored to your medical history and current condition.

2. Monitoring and Adjustments: If you decide to proceed with ECT, it is essential to have a plan for monitoring and managing any side effects. This includes regular follow-ups to assess your response to treatment and make any necessary adjustments.

3. Long-term Medication Use: Regarding your concern about the long-term use of medication like Ziprasidone (the generic name for "津普速"), there is a potential risk of metabolic side effects, including weight gain and increased risk of diabetes. Regular monitoring of blood glucose levels and metabolic parameters is advisable to mitigate these risks.

4. Quality of Life: Ultimately, the goal of any treatment is to enhance your quality of life. If ECT can help you regain the ability to work and engage socially without the burden of debilitating side effects, it may be worth considering.

In conclusion, ECT can be a valuable treatment option for schizophrenia, particularly for those who have not responded adequately to medications. However, it is essential to have a thorough discussion with your healthcare provider to ensure that you make an informed decision that aligns with your health goals and personal circumstances.

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