Persistent Urethral Redness: Seeking Solutions for Ongoing Discomfort - Urology

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Redness and swelling of the urethral opening?


Hello Doctor, I have been experiencing redness and discomfort at the urethral opening for three weeks now.
I visited several clinics and took medications, but they haven't helped.
The doctors said my urine tests were normal.
Later, I went to a major hospital where the doctor also found nothing in the tests and prescribed doxycycline for 7 days, asking me to return for a follow-up next week.
Today is my second day on the medication, but I still haven't seen any improvement.
Occasionally, I feel a dull pain in my testicles and some lower back discomfort.
The urethral opening remains red and swollen, but I have not had any discharge at all.
Do you have any suggestions, Doctor? Thank you.

Xyz, 20~29 year old female. Ask Date: 2016/12/30

Dr. Du Shixi reply Urology


Hello: Drink plenty of water (urine should be light in color), avoid beverages, spicy foods, and alcohol.
Engage in physical activity for at least half an hour each day.
If possible, discontinue unnecessary medications (doxycycline can be continued).
Additionally, avoid using ointments or any foreign substances in contact with the urethral opening for the time being.
Thank you for your inquiry.

Reply Date: 2016/12/30

More Info


Persistent urethral redness and discomfort can be quite distressing, especially when it lasts for an extended period, as you described. Given that you have already consulted multiple doctors and undergone urine tests that returned normal results, it is essential to consider several potential causes and treatment options.

First, it is important to understand that persistent urethral symptoms can arise from various conditions, including infections, inflammation, or even non-infectious causes. Since you mentioned that your urine tests were normal and you have not experienced any discharge, it is possible that you may be dealing with a non-infectious urethritis or another underlying condition.

One potential cause of your symptoms could be a condition known as non-gonococcal urethritis (NGU), which is often caused by irritation or inflammation of the urethra without a detectable infection. This can occur due to various factors, including chemical irritants (such as soaps, lotions, or even certain laundry detergents), trauma, or even sexually transmitted infections that may not be easily detected through standard urine tests.

Another possibility is that you may be experiencing a condition known as urethral syndrome, which is characterized by symptoms similar to those of a urinary tract infection (UTI) but without the presence of bacteria in the urine. This syndrome can be challenging to diagnose and may require a more comprehensive evaluation, including a thorough history, physical examination, and possibly additional tests such as a cystoscopy to visualize the urethra and bladder.

The fact that you are experiencing occasional testicular pain and lower back discomfort could suggest that there may be a more systemic issue at play, such as a referred pain from the pelvic region or even a condition affecting the prostate, such as prostatitis. Prostatitis can sometimes present with urethral discomfort and may not always show clear signs in urine tests.

As for the treatment you are currently undergoing with doxycycline, it is a broad-spectrum antibiotic that is often used to treat bacterial infections, including some forms of urethritis. However, if your symptoms do not improve after completing the course, it may be necessary to reassess the diagnosis.
Here are some recommendations for you:
1. Follow Up with Your Doctor: Since you are scheduled for a follow-up appointment, make sure to discuss your ongoing symptoms in detail. It may be helpful to keep a symptom diary, noting when the discomfort occurs, any activities that exacerbate it, and any other associated symptoms.

2. Consider a Urologist Consultation: If you haven't already, consider seeing a urologist who specializes in urinary tract disorders. They may offer additional insights or diagnostic tests that can help identify the underlying cause of your symptoms.

3. Avoid Irritants: In the meantime, try to avoid any potential irritants that could be contributing to your symptoms. This includes avoiding scented soaps, lotions, and other personal care products that may come into contact with the genital area.

4. Hydration and Diet: Staying well-hydrated can help flush out any potential irritants from your urinary system. Additionally, consider avoiding caffeine, alcohol, and spicy foods, as these can sometimes exacerbate urinary symptoms.

5. Pain Management: For the discomfort you are experiencing, over-the-counter pain relievers such as ibuprofen or acetaminophen may help alleviate some of the pain and inflammation.

6. Explore Other Causes: If symptoms persist, further evaluation may be necessary to rule out other conditions such as interstitial cystitis, pelvic floor dysfunction, or even sexually transmitted infections that may require specific testing.

In conclusion, while it can be frustrating to deal with persistent urethral symptoms without a clear diagnosis, continued communication with your healthcare providers and a thorough evaluation will be key to finding relief. Don't hesitate to advocate for yourself and seek further testing or referrals if necessary. Your health and comfort are paramount, and there are often multiple avenues to explore in search of a solution.

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