Comparing Sleep Medications: Clonazepam and Dormicum vs. Lendormin - Psychiatry

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Medications for Insomnia and Medication Switching


Hello, doctor.
I have a few questions:
1.
How does the efficacy of one Clonazepam (CLONOPAN) combined with one Dormicum Roche Film-Coated Tablet compare to the efficacy of a single dose of Zolpidem (戀多眠)? Which one is stronger?
2.
I am currently experiencing insomnia due to menopause.
I initially took one Kinax (景安寧) tablet, but it did not improve my sleep (I couldn't sleep at all through the night).
I then switched to Clonazepam and Dormicum, but I only sleep for about two hours before waking up.
Sometimes I can lie down and fall back asleep briefly, but I have strange dreams and do not sleep deeply.
Could the vivid dreaming be a side effect of Dormicum?
3.
If I need to switch medications, can I do so directly? My doctor prescribed a one-month supply of medication, and due to health insurance limitations, I cannot return for a follow-up appointment.
Therefore, I wanted to consult with you first.
Thank you.

eva, 40~49 year old female. Ask Date: 2016/12/31

Dr. Wu Enliang reply Psychiatry


Hello Eva,
1.
Dormicum has a short duration of effect but induces sleep quickly, while clonazepam is primarily an anxiolytic with a longer duration of sleep maintenance, making it difficult to compare their effectiveness directly.

2.
There are many reasons for vivid dreaming, and in your case, it may be due to light sleep, which can lead to frequent dreaming.
It cannot be solely attributed to the side effects of sleeping pills.

3.
Any medication changes should be discussed with your doctor; do not switch medications on your own.
If a change is necessary but the insurance coverage period has not yet been reached, you may consider adjusting the medication on a self-pay basis.

Reply Date: 2016/12/31

More Info


When comparing sleep medications like Clonazepam (often referred to as Clonopan), Dormicum (Midazolam), and Lendormin (Zolpidem), it's important to understand their pharmacological properties, effects, and potential side effects.

1. Comparative Efficacy: Clonazepam is primarily an anxiolytic medication that belongs to the benzodiazepine class. It is effective in reducing anxiety and can help with sleep due to its sedative properties, but it is not specifically designed as a sleep aid. Dormicum, on the other hand, is a short-acting benzodiazepine that is often used for inducing sleep quickly. It has a rapid onset of action, making it effective for those who have difficulty falling asleep. Lendormin (Zolpidem) is a non-benzodiazepine sleep aid that is specifically designed to treat insomnia. It generally has a shorter half-life than Clonazepam, which means it can help with sleep initiation without causing prolonged sedation the next day.

In terms of strength, it is challenging to directly compare these medications because they serve slightly different purposes. If your primary issue is falling asleep, Dormicum or Lendormin may be more effective than Clonazepam alone. However, if anxiety is a significant factor contributing to your insomnia, Clonazepam may provide additional benefits.

2. Dreaming and Sleep Quality: The phenomenon of vivid or strange dreams can be influenced by several factors, including the medications you are taking. While Dormicum can cause some alterations in sleep architecture, leading to lighter sleep and potentially more vivid dreams, it is not solely responsible for this effect. The combination of Clonazepam and Dormicum may lead to fragmented sleep, which can result in waking up after only a couple of hours and experiencing unusual dreams. It is essential to discuss these experiences with your healthcare provider, as they may suggest adjusting your medication regimen or exploring alternative treatments.

3. Medication Switching: When considering switching medications, it is crucial to consult with your healthcare provider. Abruptly changing medications without professional guidance can lead to withdrawal symptoms or exacerbation of your insomnia. If your doctor has prescribed a one-month supply and you are unable to see them again due to insurance constraints, it may be possible to transition to a different medication, but this should be done under medical supervision. Some medications may require a tapering schedule to minimize withdrawal effects, especially with benzodiazepines like Clonazepam.

In summary, while Clonazepam, Dormicum, and Lendormin all have sedative effects, they differ in their primary uses and side effect profiles. If you are experiencing persistent insomnia, especially related to menopause, it may be beneficial to explore non-pharmacological interventions such as cognitive-behavioral therapy for insomnia (CBT-I) alongside medication. Always prioritize open communication with your healthcare provider to ensure that your treatment plan is safe and effective for your specific situation.

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