Persistent Uveitis Symptoms: Seeking Stronger Treatment Options - Ophthalmology

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After more than a week without improvement?


Hello, I am currently studying abroad.
Two weeks ago, I had a sudden flare-up of iritis, and I have a history of this condition.
I brought my own dilating drops and 1% Alcon steroid.
When the flare-up lasted for three days without improvement, I went to a local hospital in the UK for treatment.
However, after a week of treatment, including an intravitreal injection, my condition has not improved and is actually worse than when I first went to the hospital.
The doctor prescribed me dexamethasone sodium 0.1% every two hours and atropine 1% every two days.
I am wondering if the medication prescribed by the doctor is too mild.
Can I request stronger medication? My eye is neither red nor painful, but my vision has not recovered, and I am a bit worried.
I would appreciate your advice.
Thank you.

Ms. Chen, 30~39 year old female. Ask Date: 2017/04/24

Dr. Gao Pilin reply Ophthalmology


Dear Ms.
Chen,
Your vision may be unclear temporarily due to dilated pupils.
The pupils will gradually return to normal once the atropine is no longer used.
If there is no redness or pain, it should be in the process of resolving.
Please continue to follow up with your ophthalmologist and do not adjust your medication on your own.
Inform your doctor about your condition, and they will evaluate the situation and adjust your treatment as necessary.

The ophthalmology department at Puzi Hospital in Taiwan is open Monday to Friday from 8:00 AM to 12:00 PM and Wednesday afternoons from 1:00 PM to 4:30 PM.
Please note that online responses are for reference only; it is essential to seek medical care at a healthcare facility if needed.

I hope to have the opportunity to assist you.
Best regards,
Gao Pilin

Reply Date: 2017/04/24

More Info


Persistent uveitis, particularly in the context of a history of iritis, can be a challenging condition to manage. It is understandable that you are seeking stronger treatment options, especially given your recent experience with worsening symptoms despite receiving treatment.
Uveitis, which includes inflammation of the uveal tract (iris, ciliary body, and choroid), can have various underlying causes, including autoimmune diseases, infections, or trauma. The treatment typically involves corticosteroids to reduce inflammation and, in some cases, immunosuppressive therapy if the inflammation is chronic or recurrent.

In your case, it seems that you have been prescribed dexamethasone sodium (0.1%) and atropine (1%). Dexamethasone is a potent corticosteroid, and its use is appropriate for managing inflammation. Atropine is used to dilate the pupil and help relieve pain associated with inflammation. However, if you are not seeing improvement after a week of treatment, it may indicate that the current regimen is insufficient for your specific condition.

Here are some considerations and recommendations based on your situation:
1. Assessment of Treatment Efficacy: It is crucial to evaluate why the current treatment is not yielding the desired results. Factors such as the severity of the inflammation, the presence of other underlying conditions, or even the possibility of a secondary infection should be considered. If the inflammation is severe or if there is a risk of complications, a more aggressive treatment approach may be warranted.

2. Requesting Stronger Medication: If you feel that your symptoms are not improving, it is reasonable to discuss your concerns with your healthcare provider. You can ask if there are stronger corticosteroids available or if an increase in the frequency of your current medication is possible. In some cases, oral corticosteroids or even immunosuppressive agents may be necessary if topical treatments are ineffective.

3. Monitoring for Complications: Persistent uveitis can lead to complications such as glaucoma, cataracts, or vision loss. Regular follow-up appointments with an ophthalmologist are essential to monitor your condition and adjust treatment as needed.

4. Alternative Therapies: Depending on the underlying cause of your uveitis, additional treatments may be beneficial. For example, if an autoimmune condition is contributing to your symptoms, disease-modifying antirheumatic drugs (DMARDs) or biologics may be considered.
5. Lifestyle and Supportive Measures: While awaiting further treatment adjustments, ensure you are taking care of your overall eye health. This includes avoiding eye strain, protecting your eyes from bright lights, and maintaining a healthy diet rich in anti-inflammatory foods. Staying hydrated and managing stress can also support your immune system.

6. Communication with Your Healthcare Provider: It is essential to maintain open communication with your healthcare team. If you feel that your concerns are not being addressed, consider seeking a second opinion from another ophthalmologist, particularly one specializing in uveitis or inflammatory eye diseases.

In summary, while dexamethasone and atropine are appropriate treatments for uveitis, if you are not experiencing improvement, it is important to advocate for yourself and discuss alternative or more aggressive treatment options with your healthcare provider. Persistent symptoms warrant a thorough reassessment to ensure that you receive the most effective care possible.

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