Concerns About Taking Wellbutrin: Effects on Sexual Health and Fertility - Pharmacology

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Questions about taking Prozac?


Dear Doctor, I have obsessive-compulsive disorder and have been taking 2 capsules of Paxil (the green and beige capsules) in the morning and 2 in the evening for several years.
I noticed on the medication packaging that one of the side effects is decreased libido.

1.
If I engage in sexual intercourse with my girlfriend and ejaculate inside her or perform oral sex and she ingests my semen, will it affect her body in any way? I am very concerned about the impact on her health.

2.
Will continued use of this medication lead to infertility in the future?

Nìmíng, 20~29 year old female. Ask Date: 2017/05/25

Dr. Hou Fangmin reply Pharmacology


Hello: Side effects of Wellbutrin (Bupropion): 1.
Common: headache, tension, anxiety, insomnia, nausea, diarrhea.
2.
Occasionally: rash, urticaria, and others including fever, lymphadenopathy, proteinuria, mild elevation of transaminases, drowsiness, fatigue, tremors, dizziness, palpitations, itching, myalgia, arthralgia, sexual dysfunction.
3.
Side effects vary from person to person and may not occur; they are occasional.
It has been confirmed that this medication does not cause infertility, so you do not need to worry.
However, it is best for women taking this medication to avoid pregnancy.
You can inform your physician that you are planning to conceive, and they may switch you to a medication that is safe during pregnancy.
4.
Regarding the impact of semen on the female body, this question can be directed to an obstetrician-gynecologist.
Wishing you peace and joy.

Reply Date: 2017/05/25

More Info


When considering the use of Wellbutrin (bupropion), especially in the context of sexual health and fertility, it's important to understand both the medication's effects and the implications for sexual partners. Wellbutrin is primarily prescribed for depression and anxiety disorders, and while it can be effective, it does come with a range of potential side effects.

1. Effects on Sexual Health: One of the known side effects of Wellbutrin is its potential to affect sexual desire and function. While some individuals may experience a decrease in libido, others might find that their sexual function remains unaffected or even improved compared to other antidepressants, particularly SSRIs, which are more commonly associated with sexual dysfunction. However, the impact can vary significantly from person to person.
2. Impact on Partners: Regarding your concerns about sexual activity, including ejaculation and the potential effects on your girlfriend, it is important to note that the active ingredients in Wellbutrin do not transfer through semen in a way that would directly impact a partner's health or fertility. The primary concern would be if you are experiencing side effects that could affect your sexual performance or desire, which could indirectly affect your relationship and sexual experiences.
3. Fertility Concerns: As for the long-term use of Wellbutrin and its effects on fertility, current research does not indicate that Wellbutrin causes infertility in men or women. While some medications can have an impact on sperm quality or ovulation, Wellbutrin is not typically associated with such effects. However, if you have concerns about fertility, it is always a good idea to discuss these with your healthcare provider, who can provide personalized advice based on your health history and any other medications you may be taking.

4. Communication with Partners: Open communication with your girlfriend about your concerns and any side effects you may be experiencing is crucial. If you notice changes in your sexual health or if your girlfriend has any concerns, it may be beneficial to consult with a healthcare professional together. This can help alleviate worries and ensure both partners are informed and comfortable.

5. Monitoring Side Effects: If you are experiencing significant side effects from Wellbutrin, such as a marked decrease in libido or other sexual dysfunction, it may be worth discussing with your doctor. They might consider adjusting your dosage or exploring alternative treatments that may have fewer sexual side effects.

In summary, while Wellbutrin can have effects on sexual health, it does not directly affect fertility or pose a risk to partners through sexual activity. If you have ongoing concerns, particularly regarding the impact on your relationship or your girlfriend's health, consulting with a healthcare provider is the best course of action. They can provide tailored advice and support based on your specific situation.

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