Creatinine, Glomerular Filtration Rate, Health Checkup Issues?
Hello, doctor.
I apologize for bothering you, but I would like to ask a question.
About two months ago, I went to a health check-up at a clinic.
The doctor reviewed my report and said that my liver and kidney functions were normal.
However, I still have some doubts based on what I've read online.
My creatinine level is 1.10, my glomerular filtration rate (GFR) is 86.69, urine occult blood is negative, urine protein qualitative test is negative, and I have trace ketones.
My blood pressure is slightly elevated, and my cholesterol level is 279.
At that time, my weight was 126 pounds, but I have since lost weight and am now at 119 pounds.
My height is 175 cm, and the tests were conducted after an 8-hour fasting period.
I read online that a GFR of 86.69 might indicate stage 2 chronic kidney disease.
Also, what does trace ketones mean? Could you please clarify this for me? Thank you.
Yang, 20~29 year old female. Ask Date: 2017/06/22
Dr. Wu Jiyu reply Internal Medicine
Hello Mr.
Yang: "Creatinine 1.10, Glomerular Filtration Rate (GFR) 86.69" is only a single data point, making it difficult to assess the overall kidney function.
Changes in kidney function need to be evaluated through multiple blood tests over time to understand the condition better.
According to online resources, "under the premise of long-term and stable kidney function (indicating no significant fluctuations)," a GFR of 86.69 is classified as "Stage 2 Chronic Kidney Disease." I recommend that you have follow-up blood tests in about 6-12 months.
During this period, monitor your blood pressure, weight, control your diet, and engage in moderate exercise.
The presence of trace ketones in the urine is a laboratory finding that is generally of little clinical significance.
Ketones are produced during the metabolism of fatty acids and are usually quickly metabolized and excreted by the kidneys.
They may sometimes be detected in the urine, especially if you have fasted the night before the test.
"Blood pressure is elevated, cholesterol is 279, and weight was 126 but has now decreased to 119, with a height of 175." I believe these are the key issues you need to focus on: "high blood pressure, high cholesterol, and obesity." Keep it up! Work on improving these conditions, and I believe your kidney function can remain stable! Thank you for your inquiry!
Reply Date: 2017/06/22
More Info
Understanding kidney function and the significance of creatinine levels is crucial for assessing overall health, particularly in the context of routine health checkups. Your inquiry touches on several important aspects of kidney health, including creatinine levels, glomerular filtration rate (GFR), and the implications of urine tests.
Firstly, let's discuss creatinine. Creatinine is a waste product generated from muscle metabolism and is typically filtered out of the blood by the kidneys. The normal range for serum creatinine is generally between 0.6 to 1.2 mg/dL, but this can vary based on factors such as age, sex, and muscle mass. In your case, a creatinine level of 1.10 mg/dL falls within the normal range, suggesting that your kidneys are functioning adequately in terms of filtering this waste product from your bloodstream.
Next, the glomerular filtration rate (GFR) is a critical measure of kidney function. It estimates how well your kidneys are filtering blood, with a normal GFR being above 90 mL/min/1.73m². Your reported GFR of 86.69 mL/min indicates that you are in the borderline range. While this value does not automatically classify you as having chronic kidney disease (CKD), it does suggest that you should be monitored closely, especially if there are other risk factors present, such as high blood pressure or elevated cholesterol levels.
Regarding your concern about being classified as having stage 2 CKD, the classification of chronic kidney disease is based on GFR and the presence of kidney damage. Stage 1 CKD is defined as a GFR of 90 or above with kidney damage, while stage 2 is characterized by a GFR between 60 and 89. Since your GFR is slightly below 90, it is essential to consider other factors, including any signs of kidney damage (such as proteinuria or hematuria) and your overall health profile.
You mentioned that your urine tests showed negative results for urine protein and urine blood, which is a positive sign indicating that there is no significant kidney damage at this time. The trace level of ketones in your urine could be related to several factors, including dietary influences, fasting, or even dehydration. Ketones are produced when the body breaks down fat for energy, which can occur in situations such as prolonged fasting or low carbohydrate intake. If you are not on a ketogenic diet or have not been fasting, it may be worth discussing this finding with your healthcare provider to rule out any underlying metabolic issues.
In summary, while your creatinine level is normal and your urine tests do not indicate significant kidney damage, your GFR suggests that you should be vigilant about your kidney health. Regular monitoring, maintaining a healthy lifestyle, managing blood pressure, and addressing any other risk factors (like high cholesterol) are essential steps in preserving kidney function. If you have further concerns or experience changes in your health, it is advisable to consult with a nephrologist or your primary care physician for a comprehensive evaluation and personalized recommendations.
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