Tourette Syndrome: Causes and Treatment Options - Neurology

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Tourette syndrome


My son has been diagnosed with suspected Tourette syndrome, experiencing intermittent twitching in his right hand and occasional rightward eye movement that causes his head to turn to the right.
Could you please provide information on the causes and treatment options? Thank you, Li Shuhui.

ann, 30~39 year old female. Ask Date: 2000/11/22

Dr. Huang Yingzhe reply Neurology


It is currently believed that excessive dopamine reactivity is caused by genetic factors, often associated with Attention Deficit Hyperactivity Disorder (ADHD) or Obsessive-Compulsive Disorder (OCD).
Pharmacological treatment also targets the involuntary movements and associated conditions.
For detailed medication information, please consult your psychiatrist or neurologist.
Thank you.

Reply Date: 2000/11/22

More Info


Tourette Syndrome (TS) is a neurodevelopmental disorder characterized by the presence of multiple motor tics and one or more vocal tics. The exact cause of TS is not fully understood, but it is believed to involve a combination of genetic, environmental, and neurological factors. Research suggests that abnormalities in certain brain regions, particularly those involved in the regulation of movement and behavior, may contribute to the development of tics. Additionally, there is evidence that TS can run in families, indicating a genetic predisposition.

The symptoms of Tourette Syndrome typically begin in childhood, often between the ages of 5 and 10. Tics can vary in severity and may wax and wane over time. Motor tics may include movements such as blinking, head jerking, or shoulder shrugging, while vocal tics can involve sounds like throat clearing, grunting, or even more complex utterances. In your case, the right hand's involuntary movements and the eye and head turning could be classified as motor tics.

When it comes to treatment options for Tourette Syndrome, the approach is often individualized based on the severity of the tics and the impact they have on the child's daily life. Here are some common treatment strategies:
1. Behavioral Therapy: One of the most effective non-pharmacological treatments for TS is Comprehensive Behavioral Intervention for Tics (CBIT). This therapy helps individuals become more aware of their tics and teaches them strategies to manage or suppress them.

2. Medications: If tics are severe and interfere significantly with daily functioning, medication may be considered. Commonly prescribed medications include:
- Haloperidol: An antipsychotic that has been used for many years to treat TS.

- Pimozide: Another antipsychotic that is often effective for managing tics.

- Clonidine: Originally used for high blood pressure, it can help reduce tics and is sometimes used in children with TS.

- Guanfacine: Similar to clonidine, it can help with both tics and associated behavioral issues like ADHD.

3. Supportive Therapies: In addition to behavioral therapy, supportive therapies such as occupational therapy or counseling can help children cope with the social and emotional challenges associated with TS.

4. Education and Support: Educating both the child and their family about TS is crucial. Support groups can also provide a sense of community and understanding.

5. Monitoring and Follow-Up: Regular follow-up with healthcare providers is important to monitor the condition and adjust treatment as necessary.

It's important to note that many children with Tourette Syndrome experience a reduction in symptoms as they reach adolescence and adulthood. While some may continue to have tics, others may find that their tics diminish significantly over time.

In your situation, it would be beneficial to consult with a pediatric neurologist or a psychiatrist who specializes in movement disorders. They can provide a comprehensive evaluation and discuss the best treatment options tailored to your child's specific needs.

In conclusion, Tourette Syndrome is a complex disorder with various treatment options available. Early intervention and a supportive environment can greatly enhance the quality of life for individuals with TS. If you have further questions or concerns, don't hesitate to reach out to a healthcare professional who can provide guidance and support.

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