Your Heart Medications: Safety and Interactions Explained - Cardiology

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Boshumai and Katie Heart. Kanken之间?


I am currently taking half a tablet of Concor 1.25 mg after breakfast daily, along with Kadyum extended-release tablets, Higeron, Aspirin capsules (100 mg), Rosuvastatin, and Pantoprazole.
My blood pressure has consistently remained below 140/95, with a heart rate around 70.
However, last night my blood pressure unexpectedly rose to between 165/111 and 150/100, with a heart rate of 85 to 100.
I experienced mild dizziness accompanied by severe nausea.
Today, I consulted another cardiologist who prescribed Bosentan 8 mg and Metoclopramide, advising me to take these along with my existing medications.

Since there were many patients waiting, I didn’t want to ask too many questions.
I would like to know if there are any overlapping effects among these medications.
I understand that Concor (a beta-blocker) and Bosentan (an angiotensin receptor blocker) both lower blood pressure and reduce heart rate, and that Kadyum (a calcium channel blocker) is also an antihypertensive medication.
Regarding the two gastrointestinal medications, can I temporarily stop one of them? Or can I take Bosentan in the evening to differentiate it from the morning medications? Am I overthinking this? Thank you for your guidance.

Mr. Zhang, 50~59 year old female. Ask Date: 2017/07/21

Dr. Li Han reply Cardiology


Hello, regarding your inquiry: "I am currently taking half a tablet of Kankin 1.25 after breakfast daily, along with Kady extended-release tablets, Xigema, aspirin capsules (100 mg), Guanfitol, and Weili Zhan." "My blood pressure has consistently remained below 140/95 with a heart rate around 70.
However, last night my blood pressure suddenly increased to between 165/111 and 150/100, with a heart rate of 85 to 100.
I experienced mild dizziness accompanied by severe nausea!!" "Today, I consulted another cardiologist who prescribed Bosentan 8 mg and Weiminglong, advising me to take these along with my original medications." "Since there were many patients waiting, I didn't dare to ask further questions.
Now I would like to know if there are any overlaps with the medications mentioned above?" I believe your question should not be asked online, as the information you have is only partial, and what online doctors know is also limited.
This does not assist in your long-term care.
Please schedule an appointment with your trusted attending physician.
Modern medicine emphasizes evidence-based practice, and the benefits and risks are not always a simple matter of right or wrong...
The Changhua Hospital of the Ministry of Health and Welfare cares about you.

Reply Date: 2017/07/21

More Info


Understanding your heart medications and their interactions is crucial for managing your cardiovascular health effectively. Based on the medications you mentioned—Kankun (Carvedilol), Kadyxin (Diltiazem), Higerma (Amlodipine), Aspirin, Rosuvastatin, and the two gastric medications (likely Famotidine and another)—let’s break down their functions, potential interactions, and considerations for your treatment plan.


Overview of Your Medications
1. Kankun (Carvedilol): This is a non-selective beta-blocker that helps lower blood pressure and heart rate. It is often prescribed for heart failure and hypertension.

2. Kadyxin (Diltiazem): A calcium channel blocker that also lowers blood pressure and heart rate. It works by relaxing the blood vessels and reducing the workload on the heart.

3. Higerma (Amlodipine): Another calcium channel blocker, primarily used for hypertension and angina. It helps to relax the blood vessels, improving blood flow.

4. Aspirin (100 mg): An antiplatelet medication that helps prevent blood clots, reducing the risk of heart attack and stroke.

5. Rosuvastatin: A statin used to lower cholesterol levels, which is important for preventing cardiovascular diseases.

6. Gastric Medications (likely Famotidine and another): These are used to reduce stomach acid and treat conditions like GERD or ulcers.


Blood Pressure and Heart Rate Concerns
You mentioned experiencing a sudden increase in blood pressure and heart rate, accompanied by dizziness and severe nausea. This could be due to several factors, including medication interactions, stress, or even dietary influences. It’s essential to monitor these symptoms closely, especially since you have a history of hypertension.


Potential Interactions
1. Kankun and Kadyxin: Both medications lower blood pressure and heart rate, which can lead to additive effects. If you notice excessive dizziness or fatigue, it may be worth discussing with your doctor the possibility of adjusting dosages or timing.

2. Kadyxin and Higerma: Since both are calcium channel blockers, using them together can also lead to lowered blood pressure and heart rate. However, they work through different mechanisms, so they can be complementary if monitored correctly.

3. Gastric Medications: Generally, medications like Famotidine do not interact significantly with your cardiovascular medications. However, if you are taking two different gastric medications, it may be worth discussing with your doctor whether you can reduce to one, especially if you are not experiencing severe symptoms.


Timing of Medications
Regarding the timing of your medications, it is often beneficial to space out medications that lower blood pressure to avoid potential cumulative effects. Taking one in the morning and one in the evening can help maintain more stable blood pressure throughout the day. However, this should be done under the guidance of your healthcare provider.


Recommendations
1. Consult Your Doctor: Given your recent symptoms and the addition of new medications, it’s crucial to have a follow-up appointment with your healthcare provider. Discuss your concerns about blood pressure spikes, dizziness, and nausea.

2. Monitor Symptoms: Keep a log of your blood pressure readings, heart rate, and any symptoms you experience. This information will be valuable for your doctor in adjusting your treatment plan.

3. Lifestyle Modifications: Alongside medication, consider lifestyle changes such as a heart-healthy diet, regular exercise, and stress management techniques. These can significantly impact your blood pressure and overall heart health.

4. Medication Adherence: Ensure you take your medications as prescribed. If you have concerns about side effects or interactions, do not hesitate to discuss these with your doctor rather than making changes on your own.

In summary, understanding your medications and their interactions is vital for managing your cardiovascular health. Regular communication with your healthcare provider will help ensure that your treatment plan is effective and safe.

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