Can Chronic Kidney Disease Be Treated with Medications?

Is there medication available to treat chronic kidney disease?

Hello Doctor: My mother previously suffered from a myocardial infarction, which has affected her kidney function.
Her current creatinine level is 2.23, and the doctor has indicated that she is in stage 4 chronic kidney disease.
She is regularly visiting a nephrologist, but I noticed that the medications prescribed by the nephrologist seem to be nutritional supplements, including Folacin (folic acid) and Hi-Beston, which provide folic acid and vitamins B2, B6, and B12.
These do not seem to be specific treatment medications like those prescribed by the cardiologist for preventing myocardial infarction and other specific conditions.
Therefore, I have been wondering if there are no medications available for treating chronic kidney disease.
Thank you, Doctor.

Liao Mingquan, 30~39 year old female. Ask Date: 2017/07/23

Dr. Wu Jiyu reply Internal Medicine

Based on your description, your aunt has a history of myocardial infarction and may also have issues related to the "three highs" (hypertension, hyperglycemia, and hyperlipidemia).
From the perspective of chronic kidney disease management, controlling these conditions is a primary requirement.
In addition to medication, dietary control and exercise should be implemented together; this is the essential approach to managing chronic kidney disease.
It is recommended that during the next follow-up appointment, you confirm with the physician whether the "three highs" are under control and consult with a chronic kidney disease educator on dietary and exercise management (such as whether a low-phosphorus, low-potassium, or low-protein diet is necessary).
Thank you for your inquiry; the Nephrology Department at Changhua Hospital cares about your well-being.

Reply Date: 2017/07/23

More Info

Chronic Kidney Disease (CKD) is a progressive condition characterized by a gradual loss of kidney function over time. It is essential to understand that while there is no cure for CKD, there are various treatment strategies aimed at managing the disease, slowing its progression, and addressing its complications. The treatment approach often involves a combination of medications, dietary modifications, and lifestyle changes.

In your mother's case, with a creatinine level of 2.23 indicating stage 4 CKD, the focus of treatment is primarily on managing the underlying causes and preventing further deterioration of kidney function. The medications prescribed by her nephrologist, such as Folacin (folic acid) and Hi-Beston (which contains vitamins B2, B6, and B12), are indeed supportive therapies. These vitamins play a crucial role in maintaining overall health and can help mitigate some complications associated with CKD, such as anemia and bone health issues.
One of the primary goals in managing CKD is to control comorbid conditions, particularly hypertension, diabetes, and hyperlipidemia (high cholesterol), which can exacerbate kidney damage. Medications such as ACE inhibitors or ARBs (Angiotensin Receptor Blockers) are commonly prescribed to manage blood pressure and provide renal protection. If your mother has any of these conditions, it would be essential to discuss with her nephrologist whether these medications are appropriate for her.

Dietary management is another critical aspect of CKD treatment. Patients are often advised to follow a renal diet, which may include restrictions on protein, sodium, potassium, and phosphorus intake, depending on the stage of kidney disease and individual lab results. A registered dietitian specializing in kidney disease can provide personalized dietary recommendations to help manage her condition effectively.

In addition to medications and dietary changes, lifestyle modifications such as regular physical activity, smoking cessation, and weight management are vital for improving overall health and potentially slowing the progression of CKD.
Regarding your concern about the lack of specific medications for CKD, it is important to note that while there are no medications that can reverse kidney damage, there are treatments available to manage symptoms and complications. For instance, erythropoiesis-stimulating agents (ESAs) may be used to treat anemia, and phosphate binders can help manage elevated phosphorus levels. In advanced stages of CKD, patients may require dialysis or kidney transplantation.

In summary, while there is no definitive cure for CKD, various medications and treatment strategies can help manage the disease and improve quality of life. It is crucial to maintain regular follow-ups with her nephrologist to monitor her kidney function and adjust her treatment plan as needed. Open communication with her healthcare team about any concerns or questions regarding her medications and overall management will be beneficial in ensuring she receives comprehensive care.

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