Side Effects of Psychiatric Medications: A Patient's Concern - Psychiatry

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Drug side effects


Due to depression for four months, I am currently taking the following medications: Fuanyuan three times a day, two capsules of Rifampicin (Rifampin) at bedtime, two capsules of Clonazepam, two capsules of Duloxetine, and Amberning as needed.
Recently, I have noticed two issues: 1.
The side effects of Rifampicin are unstable; sometimes, even after more than 12 hours, I still experience weakness in my legs and slight falls, requiring support from surrounding objects.
2.
My stool has been black, and I am unsure if this is due to internal bleeding or a medication issue, so I would like to inquire about this.

RICK, 20~29 year old female. Ask Date: 2017/11/06

Dr. Liang Sunyuan reply Psychiatry


Hello Rick: 1.
If you are still experiencing instability after taking medication for more than 12 hours, it is advisable to return to the clinic and discuss with your physician whether a medication adjustment is necessary.
2.
If you notice black stools, first consider whether any recent foods could have caused this.
Currently, your medication should not be responsible for the occurrence of black stools.
If this symptom persists, it is recommended to consult a gastroenterologist for a thorough examination.
Best wishes to you.

Reply Date: 2017/11/06

More Info


When it comes to managing depression and the associated side effects of psychiatric medications, it is crucial to approach the situation with care and a thorough understanding of the medications involved. Your concerns regarding the side effects of the medications your mother is taking, particularly the issues of weakness and black stools, warrant immediate attention and discussion with a healthcare professional.

Firstly, let's address the medications your mother is currently taking: Lexaton, Ramerson, Ala 36, Xanax, and Dogmatil. Each of these medications can have various side effects, and it is not uncommon for patients to experience adverse reactions, especially when multiple medications are involved. The symptoms you described—severe shoulder pain, generalized body aches, drowsiness, poor vision, decreased concentration, and anxiety—could potentially be linked to the medications or could be manifestations of her underlying depression.

1. Weakness and Dizziness: The feeling of weakness and the occasional need for support when walking can be concerning. Medications like Lexaton (which is often used for anxiety and depression) and Xanax (a benzodiazepine) can cause sedation and muscle relaxation, leading to feelings of weakness or dizziness. It is essential to monitor these symptoms closely. If they persist or worsen, it may be necessary to discuss with her psychiatrist the possibility of adjusting the dosage or switching to a different medication.

2. Black Stools: The presence of black stools is particularly alarming and should not be overlooked. This symptom can indicate gastrointestinal bleeding, which could be a serious side effect of certain medications, especially if they are affecting the stomach lining. Some medications can cause irritation or ulcers in the gastrointestinal tract, leading to bleeding. It is crucial to report this symptom to her healthcare provider immediately, as they may need to conduct further evaluations, such as blood tests or an endoscopy, to determine the cause.

3. Managing Side Effects: If your mother is experiencing significant side effects, it is essential to have an open dialogue with her psychiatrist. Abruptly stopping medications can lead to withdrawal symptoms and a potential worsening of her depression. Instead, a gradual tapering of the medication under medical supervision may be necessary. The psychiatrist may also consider alternative medications or adjunct therapies that could alleviate her symptoms without causing intolerable side effects.

4. Holistic Approach: In addition to medication management, incorporating lifestyle changes can also be beneficial. Encouraging regular physical activity, a balanced diet, and good sleep hygiene can help improve mood and overall well-being. Cognitive-behavioral therapy (CBT) or other forms of psychotherapy can also provide support and coping strategies for managing depression.

5. Communication with Healthcare Providers: It is vital to maintain open lines of communication with all healthcare providers involved in your mother's care. If she is seeing multiple doctors, ensure that they are all aware of her complete medication list and any side effects she is experiencing. This coordination can help prevent drug interactions and ensure that her treatment plan is cohesive.

In summary, managing the side effects of psychiatric medications requires careful monitoring and communication with healthcare providers. The symptoms your mother is experiencing, particularly the black stools and weakness, should be addressed promptly with her psychiatrist. A collaborative approach that includes medication management, lifestyle changes, and therapy can help improve her overall mental health and quality of life. Always prioritize safety and seek immediate medical attention for concerning symptoms.

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