Can Anti-Inflammatory Medications Affect Birth Control Effectiveness? - Obstetrics and Gynecology

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Anti-inflammatory drugs and emergency contraceptive pills?


Hello Doctor: I sprained my ankle yesterday, and when I saw the doctor today, they prescribed anti-inflammatory medication for me.
However, I had unprotected intercourse with my boyfriend yesterday, but there was no ejaculation inside.
I would like to ask: 1.
I am currently on my second pack of Pristina; will today's anti-inflammatory medication affect the contraceptive effectiveness and increase the possibility of pregnancy from yesterday's encounter? 2.
If I take the anti-inflammatory medication for the next two days, should I wait until after finishing the medication to take the emergency contraceptive for seven days before having unprotected intercourse again? 3.
Additionally, I have seen information stating that citrus and grapefruit can affect the effectiveness of contraceptive pills; does this mean that oranges will also affect the contraceptive effectiveness? Thank you, Doctor!

Niming, 20~29 year old female. Ask Date: 2017/11/06

Dr. Huang Jianzhong reply Obstetrics and Gynecology


I sprained my ankle yesterday, and when I saw the doctor today, he prescribed anti-inflammatory medication for me.
However, I had unprotected sex with my boyfriend yesterday, but there was no ejaculation.
I would like to ask:
1.
I am currently taking my second pack of Qlaira.
Will today's anti-inflammatory medication affect the contraceptive effectiveness and increase the possibility of pregnancy from yesterday's encounter?
Answer: Anti-inflammatory medication will not affect contraceptive effectiveness.
2.
If I take the anti-inflammatory medication for the next two days, should I wait until after finishing the anti-inflammatory medication to take the seven days of the contraceptive pill before having unprotected sex again?
Answer: Anti-inflammatory medication is separate from Qlaira; the two are unrelated.
3.
Additionally, I have seen information stating that citrus fruits and grapefruit can affect the effectiveness of contraceptive pills.
Does eating oranges affect contraceptive effectiveness?
Answer: Oranges will not affect contraceptive effectiveness.

Reply Date: 2017/11/06

More Info


When it comes to the effectiveness of birth control methods, particularly hormonal contraceptives like the pill, there are several factors to consider, including the potential impact of medications such as anti-inflammatory drugs.
1. Impact of Anti-Inflammatory Medications on Birth Control: Generally, non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen do not affect the effectiveness of hormonal contraceptives. These medications work by reducing inflammation and pain but do not interfere with the hormonal mechanisms that prevent ovulation. Therefore, taking an anti-inflammatory medication after having unprotected intercourse should not increase the risk of pregnancy, especially since you mentioned that there was no ejaculation.

2. Timing of Birth Control Pills: If you are currently taking your birth control pills as prescribed, you should continue to do so even while taking anti-inflammatory medications. There is no need to wait for a certain period after finishing the anti-inflammatory medication before relying on your birth control pills again. The effectiveness of the pill remains intact as long as you take it consistently and correctly. If you are in the second pack of your birth control pills, you are likely still protected against pregnancy.

3. Effects of Citrus Fruits on Birth Control: Regarding your concern about citrus fruits, particularly grapefruit, it is true that grapefruit can interact with certain medications, including some hormonal contraceptives. Grapefruit can inhibit the enzyme CYP3A4 in the liver, which is responsible for metabolizing many drugs. However, the effect of oranges and other citrus fruits like tangerines is generally considered to be less significant. Eating oranges is unlikely to have a substantial impact on the effectiveness of your birth control pills. If you are consuming them in moderation, you should not worry about their effect on your contraceptive method.

In summary, based on current medical understanding, taking anti-inflammatory medications should not affect the effectiveness of your birth control pills. You can continue taking your pills as directed without concern for the anti-inflammatory medication you received. Additionally, consuming oranges should not pose a risk to your contraceptive effectiveness. If you have further concerns or experience any unusual symptoms, it is always best to consult with your healthcare provider for personalized advice.
Lastly, if you are ever in doubt about the interactions between medications and birth control, or if you are considering changes to your medication regimen, it is advisable to discuss these with your doctor or a pharmacist. They can provide you with the most accurate and relevant information based on your specific health situation.

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