Impact of Anti-Inflammatory Medications on Birth Control Effectiveness - Obstetrics and Gynecology

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The effectiveness of birth control pills may be influenced by the use of anti-inflammatory medications or injections during the course of taking the pills?


Hello, Doctor.
Today I visited the clinic due to a urinary tract infection, and the doctor prescribed me anti-inflammatory medication.
I would like to ask if I should take the prescribed anti-inflammatory medication today, considering that I have been taking birth control pills (Yasmin) for six months and today is the fourth pill of the sixth pack.
I had unprotected intercourse today but without ejaculation.
Is it safer to wait a few days before taking the anti-inflammatory medication? Additionally, if I receive an anti-inflammatory injection today, will it reduce the effectiveness of the birth control pills? Thank you.

Niming, 10~19 year old female. Ask Date: 2020/08/20

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it won't affect you.
You can continue taking the birth control pills as originally prescribed.
Wishing you good health.

Reply Date: 2020/08/20

More Info


When it comes to the interaction between anti-inflammatory medications and birth control effectiveness, it is essential to understand how different medications can affect hormonal contraceptives. In your case, you are currently taking a birth control pill (Yasmin) and have been prescribed anti-inflammatory medication for a urinary tract infection (UTI).
First, it is important to note that most non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, do not have any significant impact on the effectiveness of hormonal contraceptives. The primary mechanism of action for these medications is to reduce inflammation and alleviate pain, and they do not interfere with the hormonal pathways that birth control pills utilize to prevent ovulation. Therefore, taking an NSAID for your UTI should not compromise the effectiveness of your birth control pill.

However, if the anti-inflammatory medication prescribed to you is a corticosteroid (like prednisone), there is a slightly different consideration. While corticosteroids are not known to significantly affect the effectiveness of birth control pills, they can sometimes lead to changes in metabolism that might theoretically alter hormone levels. That said, the clinical evidence supporting a significant interaction is limited, and most healthcare providers agree that corticosteroids do not pose a substantial risk to the efficacy of hormonal contraceptives.

Regarding your specific situation, since you are on the fourth pill of your sixth pack and have had unprotected intercourse without ejaculation, it is crucial to continue taking your birth control pills as directed. If your doctor has prescribed anti-inflammatory medication, it is generally safe to take it concurrently with your birth control pill. However, if you have any concerns about the specific medication prescribed, it is always best to consult with your healthcare provider for personalized advice.

In terms of timing, if you are concerned about taking the anti-inflammatory medication today, you can wait a day or two to start it, but this is more about personal comfort than a necessity for maintaining contraceptive effectiveness. If you have already received an anti-inflammatory injection, it is unlikely to affect your birth control's effectiveness either.

In summary, you can safely continue taking your birth control pills while using the anti-inflammatory medication prescribed for your UTI. If you have any lingering concerns or experience any unusual side effects, do not hesitate to reach out to your healthcare provider for further clarification and guidance. It is always better to err on the side of caution and ensure you have all the information you need to make informed decisions about your health and contraceptive use.

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