Weight Gain of 15 kg in 8 Months: Is It Related to My Medications? - Internal Medicine

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Gained 15 kilograms in 8 months?


Hello, doctor: I would like to ask if gaining 15 kilograms in 8 months indicates a problem with my body.
I eat a normal amount for three meals a day and drink 3 to 4 liters of water daily.
I also exercise three times a week for one hour.
I have been taking Lyrica capsules, medications for neurogenic joint inflammation, CoQ10, and magnesium oxide for a long time.
Additionally, I receive a long-acting injection of Sustanon every two months.
I would like to know if my weight gain is related to the medications I am taking.
Which specialty should I consult for weight loss?

Baobao, 30~39 year old female. Ask Date: 2017/12/19

Dr. Zeng Guosen reply Internal Medicine


It is recommended to consult an endocrinologist for evaluation.
Thank you for your question.

Reply Date: 2017/12/19

More Info


Weight gain can be a complex issue influenced by various factors, including medications, diet, physical activity, and underlying health conditions. In your case, gaining 15 kg over eight months, despite maintaining a relatively normal diet and regular exercise, raises valid concerns about the potential impact of your medications.

Firstly, let's consider the medications you mentioned: Lyrica (pregabalin), anti-inflammatory drugs, and other supplements. Lyrica is known to cause weight gain in some individuals. This is primarily due to its effects on appetite and fluid retention. Additionally, certain anti-inflammatory medications can also contribute to weight gain, either through increased appetite or fluid retention. If you have been taking these medications consistently, they could indeed be a significant factor in your weight gain.

Moreover, the long-acting injection you receive every two months (likely referring to a hormonal treatment) can also lead to weight fluctuations. Hormonal treatments can affect metabolism, appetite, and fat distribution in the body. It's essential to discuss these concerns with your healthcare provider, as they may consider adjusting your medications or exploring alternative treatments that have a lesser impact on your weight.

In terms of your lifestyle, while you mentioned that you eat three meals a day and drink plenty of water, it’s crucial to assess the quality of your diet. Even if your portion sizes are reasonable, the types of foods you consume can significantly impact weight management. A diet high in processed foods, sugars, and unhealthy fats can lead to weight gain, even if caloric intake seems controlled. Keeping a food diary can help you identify patterns and make necessary adjustments.

Regarding your exercise routine, while you are active three times a week for an hour, the intensity and type of exercise matter. Incorporating strength training can help build muscle mass, which in turn can boost your metabolism. Additionally, consider varying your workouts to include cardiovascular exercises that elevate your heart rate and promote fat loss.

To address your question about which medical specialty to consult for weight management, an endocrinologist would be a suitable choice. They specialize in hormonal and metabolic disorders and can evaluate whether hormonal imbalances or medication side effects are contributing to your weight gain. They can also provide guidance on safe and effective weight loss strategies tailored to your specific situation.

In conclusion, while your medications may play a role in your weight gain, it’s essential to consider all aspects of your lifestyle, including diet and exercise. Consulting with an endocrinologist can provide you with a comprehensive evaluation and personalized recommendations to help you manage your weight effectively. Remember, weight management is often a multifaceted approach that requires patience and persistence.

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