Ankylosing Spondylitis: Symptoms and Insights - Orthopedics

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Ankylosing Spondylitis


Three weeks ago, I experienced pain in my lower back whenever I leaned forward or backward (it wasn't unbearable pain).
After stretching a few times, the pain subsided.
However, after sitting for a long time, leaning forward or backward would still cause pain.
For a couple of days, I felt a stiffness upon waking up (not waking up due to pain), but I didn't have any discomfort in other areas.
After about a week, I didn't feel much anymore, and the pain upon waking only occurred on those two days.
Now, about three weeks later, those symptoms have returned.
Could this be ankylosing spondylitis?

Wang Xiaodidi, 10~19 year old female. Ask Date: 2017/12/29

Dr. Shi Guozheng reply Orthopedics


Ankylosing spondylitis can cause long-term chronic lower back pain, with stiffness that makes bending difficult.
If the pain lasts only for a week, the likelihood of ankylosing spondylitis is lower.
Additionally, ankylosing spondylitis is associated with X-ray changes, where the spine may appear bamboo-like, and the joint space between the sacrum and the ilium may become obliterated, resulting in fusion.
Blood tests may reveal the presence of the HLA-B27 antigen.
A family history is also relevant, as siblings and other relatives may have the same condition.
If there are any concerns, it is advisable to visit a hospital for evaluation.

Reply Date: 2017/12/29

More Info


Ankylosing Spondylitis (AS) is a type of inflammatory arthritis that primarily affects the spine and the sacroiliac joints in the pelvis. It is characterized by chronic pain and stiffness in the back, which can lead to a progressive fusion of the vertebrae, resulting in a rigid spine. The symptoms you describe, such as lower back pain that improves with movement and stiffness upon waking, are indeed indicative of AS.
The key features of AS include:
1. Chronic Back Pain: The pain is typically worse at night or in the early morning and may improve with physical activity. This is in contrast to mechanical back pain, which often worsens with activity.

2. Morning Stiffness: Many individuals with AS experience stiffness in the morning that can last for several hours. This stiffness tends to improve as the day progresses and with movement.

3. Improvement with Exercise: Unlike typical back pain, the discomfort associated with AS often improves with physical activity and worsens with prolonged rest.

4. Age of Onset: AS commonly begins in young adulthood, typically between the ages of 15 and 30.

5. Family History: There is a genetic component to AS, with a significant association with the HLA-B27 antigen. If you have a family history of AS or related conditions, this could further support the diagnosis.

6. Other Symptoms: Some individuals may also experience symptoms outside of the spine, such as inflammation in the eyes (iritis or uveitis), which can cause redness and pain in the eye, or other joint involvement.

Given your symptoms of lower back pain that is aggravated by certain movements and the episodes of stiffness, it is reasonable to consider AS as a potential diagnosis. However, it is essential to consult a healthcare professional for a thorough evaluation, which may include imaging studies such as X-rays or MRI, and blood tests to check for the HLA-B27 antigen and inflammatory markers.

In terms of management, treatment for AS typically involves:
- Physical Therapy: Engaging in a regular exercise program can help maintain flexibility and reduce stiffness. Physical therapists can design a program tailored to your needs.

- Medications: Nonsteroidal anti-inflammatory drugs (NSAIDs) are often the first line of treatment to help manage pain and inflammation. In more severe cases, disease-modifying antirheumatic drugs (DMARDs) or biologics may be prescribed.

- Lifestyle Modifications: Maintaining a healthy weight, practicing good posture, and avoiding prolonged periods of inactivity can also be beneficial.

- Regular Follow-ups: Continuous monitoring by a rheumatologist or a specialist in inflammatory diseases is crucial to manage the condition effectively and adjust treatment as necessary.

In conclusion, while your symptoms may align with those of Ankylosing Spondylitis, a definitive diagnosis should be made by a healthcare professional. Early diagnosis and intervention can significantly improve the quality of life and prevent long-term complications associated with the disease. If you are experiencing recurrent symptoms, it is advisable to seek medical attention promptly.

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