Muscle Twitches: Are They Linked to ALS or Anxiety? - Neurology

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Muscle twitching


Hello Doctor: I experienced dizziness and weakness in my limbs at the end of December last year.
After visiting a neurology department at the hospital, an EEG showed no abnormalities.
However, I continued to feel dizzy into early January, so I switched to another hospital where I underwent auditory evoked potentials, transcranial ultrasound, and carotid ultrasound, all of which were normal.
During this time, I also mentioned to the doctor that I felt weakness in my limbs and experienced random muscle twitches.
The physician suggested that I was too anxious and that my nerves were too tense, and advised me not to return.

However, in the past week or two, I have been experiencing frequent involuntary muscle twitches all over my body, sometimes in my hands, feet, buttocks, and face, along with a feeling of lethargy and weakness in my limbs, although it’s not a true loss of strength.
After researching these symptoms online, I found that they are associated with ALS.
I wish I hadn’t looked it up, as now the muscle twitching seems more pronounced and the feeling of weakness is more intense, which has increased my anxiety.

I would like to ask the doctor if there is a definitive relationship between these involuntary muscle twitches and ALS, or if it could be related to the medications I am taking? Which specialty should I consult next? Currently, I am no longer experiencing dizziness and am taking medications including 0.25 mg of Xanax twice daily and Chang Li (a medication prescribed by the neurologist).
I would appreciate your clarification.

ERIC, 30~39 year old female. Ask Date: 2018/01/27

Dr. Jiang Junyi reply Neurology


Hello: The ALS you are concerned about primarily refers to issues with motor neurons.
Motor neurons control muscle movement; generally, the motor neurons in the brain are referred to as upper motor neurons, while those in the brainstem and spinal cord are called lower motor neurons.
When motor neurons become damaged, our muscles do not receive adequate nutrients and chemicals, which can lead to muscle death.
This is a chronic muscle-wasting disease that may result in muscle atrophy.
If upper motor neurons die, abnormal signal transmission may cause muscle twitching.
However, clinical diagnosis requires methods such as electromyography and muscle biopsy.
Neurologists specializing in neuromuscular diseases are more familiar with these types of conditions, and I recommend consulting such a specialist.
Wishing you peace and joy.
Dr.
Tao, Internal Medicine, cares about you.

Reply Date: 2018/01/27

More Info


Muscle twitches, also known as fasciculations, can be concerning, especially when they occur frequently and are accompanied by feelings of weakness or fatigue. It's understandable to worry about conditions like Amyotrophic Lateral Sclerosis (ALS), particularly when information online suggests a connection. However, it's essential to approach this topic with a clear understanding of the symptoms, potential causes, and the relationship between anxiety and muscle twitching.

Firstly, it's important to clarify that muscle twitches alone are not definitive indicators of ALS. ALS is a progressive neurodegenerative disease that primarily affects motor neurons, leading to muscle weakness, atrophy, and eventual paralysis. The diagnosis of ALS typically requires the presence of both upper motor neuron (UMN) and lower motor neuron (LMN) signs, which may include muscle weakness, atrophy, and specific findings on electromyography (EMG). In the absence of these signs, the likelihood of having ALS is significantly reduced.

In your case, the muscle twitching you are experiencing, along with the feelings of weakness, could be attributed to several factors, including anxiety. Anxiety can lead to a heightened state of arousal in the nervous system, which can manifest as muscle tension and twitching. This is often referred to as "anxiety-induced muscle twitching." When individuals are anxious, they may also become hyper-aware of bodily sensations, leading to increased focus on normal muscle movements that might otherwise go unnoticed. This can create a cycle of worry and increased muscle twitching, further exacerbating anxiety.

Additionally, the medications you mentioned, such as Zolpidem (often used for sleep disorders) and other anxiety medications, can also have side effects that include muscle twitching or spasms. It's crucial to discuss any side effects you experience with your prescribing physician, as they may need to adjust your medication or explore alternative treatments.

Given your symptoms and the previous evaluations that ruled out significant neurological issues, it may be beneficial to consider a multidisciplinary approach to your care. This could involve consulting with a neurologist for further evaluation of your muscle twitching and any potential underlying neurological conditions. Additionally, a mental health professional, such as a psychologist or psychiatrist, could help address the anxiety that seems to be contributing to your symptoms. Cognitive-behavioral therapy (CBT) is particularly effective for anxiety and can provide you with tools to manage your symptoms better.

In summary, while muscle twitching can be concerning, it is not solely indicative of ALS, especially in the absence of other neurological signs. Anxiety can significantly contribute to muscle twitching and feelings of weakness. A comprehensive evaluation by both a neurologist and a mental health professional may provide clarity and help you develop a management plan that addresses both the physical and psychological aspects of your symptoms. Remember, it's essential to communicate openly with your healthcare providers about your concerns and symptoms to receive the best possible care.

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