Blood Test Results: A Guide for Cancer Patients - Oncology

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I don't understand the blood test report?


I have a habit of donating platelets, but the center has noted abnormal results in my last three tests and referred me to a hospital for blood tests.
However, I do not understand the meaning of the values and would like to consult a physician.
Here are the reference values and my test results:
- LD: 135-225; my result: 159
- WBC: 3.2-9.2; my result: 9.9
- RBC: 3.72-4.93; my result: 4.67
- Hb: 11.6-14.8; my result: 13.5
- Hct: 33.8-43.4; my result: 40.2
- MCV: 82.7-95.5; my result: 86.2
- MCH: 28.2-33; my result: 29
- MCHC: 33.2-35.2; my result: 33.6
- RDW: 11.9-14.3; my result: 12.1
- Plt: 151-366; my result: 647
- MPV: 6.4-10; my result: 8
- Blast: 0
- Pro: 0
- Myelo: 0
- Meta: 0
- Band: 0
- Seg: 43-64; my result: 48
- Eos: 0-6; my result: 0
- Baso: 0-1; my result: 0
- Mono: 3-9; my result: 4
- Lymph: 27-47; my result: 46
- Aty-lym: 0
- NRBC: 0
P.S.
At the end of last year, my family physician performed an ultrasound and found splenomegaly.
I am unsure if this is related.

Beibei, 20~29 year old female. Ask Date: 2018/03/01

Dr. Hu Ziren reply Oncology


Thrombocytopenia (<100,000, your count is 47,000), combined with a history of splenomegaly, initially raises suspicion for "idiopathic (autoimmune) thrombocytopenic purpura." However, a definitive diagnosis requires further testing and the exclusion of other potential causes.

Reply Date: 2018/03/01

More Info


Understanding blood test results can be particularly challenging for cancer patients, especially when the results indicate abnormalities that may suggest underlying health issues. In your case, the blood test results you provided show several key indicators that warrant further discussion.


Key Blood Test Parameters
1. WBC (White Blood Cells): Your result is 3.2, which is below the normal range (4.0-9.2). A low WBC count, known as leukopenia, can indicate a weakened immune system, which may be due to various factors including bone marrow disorders, autoimmune diseases, or the effects of chemotherapy.

2. RBC (Red Blood Cells): Your result is 4.67, which falls within the normal range (3.72-4.93). This indicates that your red blood cell count is adequate, which is important for oxygen transport in the body.

3. Hemoglobin (Hb): At 13.5, your hemoglobin level is also within the normal range (11.6-14.8). Hemoglobin is crucial for carrying oxygen, and normal levels suggest that your body is effectively oxygenated.

4. Hematocrit (Hct): Your result of 40.2 is within the normal range (33.8-43.4). This indicates the proportion of blood volume that is occupied by red blood cells.

5. Platelet Count (Plt): Your platelet count is 647, which is significantly elevated compared to the normal range (151-366). Thrombocytosis can occur due to various reasons, including inflammation, infection, or bone marrow disorders.

6. Blast Cells: The presence of blast cells in the blood can be a critical indicator. In your case, the result shows "0," which is a positive sign as the presence of blast cells can indicate leukemia or other hematological malignancies.

7. Other Parameters: The MCV, MCH, and MCHC values are all within normal ranges, indicating that the red blood cells are of normal size and concentration of hemoglobin.


Interpretation and Next Steps
Given the elevated platelet count and low WBC count, it is essential to consider the context of these results. The enlarged spleen (splenomegaly) noted in your ultrasound can be related to various conditions, including myeloproliferative disorders, infections, or other hematological conditions. The spleen plays a role in filtering blood and managing blood cells, and its enlargement can indicate that it is working harder than normal, possibly due to the abnormalities in your blood counts.


Recommendations
1. Consult a Hematologist: It is crucial to discuss these results with a hematologist, who specializes in blood disorders. They can provide a more comprehensive evaluation and may recommend further testing, such as a bone marrow biopsy, to assess the health of your bone marrow and rule out any serious conditions.

2. Monitor Symptoms: Keep track of any symptoms you may experience, such as fatigue, unusual bruising or bleeding, or recurrent infections, and report these to your healthcare provider.

3. Follow-Up Testing: Regular follow-up blood tests may be necessary to monitor your blood counts over time and assess any changes.

4. Lifestyle Considerations: Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can support your overall health and immune function.

5. Stay Informed: Understanding your condition and treatment options is vital. Don’t hesitate to ask your healthcare provider for clarification on any aspect of your diagnosis or treatment plan.

In summary, while your blood test results show some abnormalities, particularly with the WBC and platelet counts, it is essential to approach this with a comprehensive evaluation from a specialist. Early intervention and monitoring can significantly impact outcomes, especially in the context of potential blood disorders.

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