Does Taking Dexamethasone for Panic Disorder Affect Blood Pressure? - Pharmacology

Share to:

Drug Information


Hello doctor, I would like to ask if taking De-Anxiu for a period of time to treat panic disorder can cause lower blood pressure and palpitations? My usual blood pressure is between 95 and 100, but after taking De-Anxiu for about three weeks, my blood pressure has been in the 80s to 92 these past two days, and I feel a bit dizzy and fatigued.
I also experience palpitations when I stand up, which I didn't have when I first started taking it.

Emily, 30~39 year old female. Ask Date: 2018/03/21

Dr. Chen Yuemei reply Pharmacology


Hello: After reviewing, the incidence of side effects such as dizziness and hypotension from taking Flupentixol is approximately 1-10%, while the incidence of tachycardia is about 0.1-1%.
It is recommended that you return to your doctor to inform them of your symptoms.

Reply Date: 2018/03/21

More Info


Dexamethasone is a corticosteroid that is often used to treat a variety of conditions, including inflammation, autoimmune disorders, and certain types of cancer. While it is not typically a first-line treatment for panic disorder, it may be prescribed in specific cases where inflammation or other related issues are present. However, it is important to understand how dexamethasone can affect blood pressure and overall health.

Corticosteroids like dexamethasone can have a range of side effects, and one of the notable effects is their impact on blood pressure. Corticosteroids can lead to fluid retention, which may increase blood volume and subsequently raise blood pressure. This is particularly relevant for individuals who may already have underlying hypertension or are at risk for high blood pressure. In some cases, patients may experience elevated blood pressure as a result of corticosteroid therapy.

On the other hand, the symptoms you are experiencing—such as low blood pressure (hypotension), dizziness, fatigue, and palpitations—are concerning and warrant further investigation. The blood pressure readings you mentioned (80s to 92) are quite low, especially if your normal range is around 95 to 100. These symptoms could be indicative of several factors, including the effects of the medication you are taking, potential interactions with other medications, or even the underlying panic disorder itself.

It is also worth noting that certain medications used to treat panic disorder, such as selective serotonin reuptake inhibitors (SSRIs) or benzodiazepines, can have varying effects on blood pressure. While SSRIs are generally considered safe and may not significantly affect blood pressure, some individuals may experience side effects that could lead to fluctuations in blood pressure. Benzodiazepines, on the other hand, can cause sedation and may lead to dizziness, especially when standing up quickly, which could explain your feelings of lightheadedness.

Given your symptoms and the recent changes in your blood pressure, it is crucial to consult with your healthcare provider. They can evaluate your current medication regimen, assess for any potential drug interactions, and determine whether adjustments are necessary. It may also be beneficial to monitor your blood pressure regularly and keep a log of your readings to provide your doctor with detailed information.

In summary, while dexamethasone can potentially affect blood pressure, the symptoms you are experiencing may be multifactorial. It is essential to have an open dialogue with your healthcare provider to address these concerns and ensure that your treatment plan is safe and effective. They may consider alternative treatments or adjustments to your current medications to help manage both your panic disorder and any blood pressure issues you are facing.

Similar Q&A

Managing Panic Disorder and Hypertension: Insights and Strategies for Relief

Hello, Doctor. I have been taking medication for panic disorder (Xanax 0.5mg) for nearly twenty years, and I also have hypertension, which I manage with medication (Micardis/Concor). Whenever I experience a panic attack, my blood pressure spikes to a systolic pressure of 140-160 ...


Dr. Wu Zongying reply Family Medicine
Hello: There are many factors that can affect high blood pressure. The prevalence of hypertension is higher among modern individuals, primarily due to lifestyle factors such as stress and tension, which can lead to increased secretion of adrenaline in the endocrine system, result...

[Read More] Managing Panic Disorder and Hypertension: Insights and Strategies for Relief


Understanding Autonomic Nervous System Dysregulation and Panic Disorder

Hello, doctor. Due to long-term night shifts, I have experienced multiple episodes in the past two months where I suddenly feel palpitations and my heart is pounding strongly, accompanied by a noticeable heartbeat sound. My blood pressure has soared to 180-190/100-119 during thes...


Dr. Lin Mianzhang reply Psychiatry
Hello Ah-Hua: I apologize for the delayed response as I did not receive a notification for your question. If your blood pressure remains uncontrolled despite taking antihypertensive medication, you may need to discuss with a cardiologist whether a medication adjustment is necessa...

[Read More] Understanding Autonomic Nervous System Dysregulation and Panic Disorder


Understanding Anxiety and Its Impact on Blood Pressure: A Guide

Hello, Doctor: I often feel inexplicably anxious, with a rapid heartbeat and a sensation of shortness of breath. Whenever this happens, my blood pressure tends to rise, with a recorded high of 140/105. I previously had an electrocardiogram, and the report was normal. My usual blo...


Dr. Li Dong'an reply Internal Medicine
Hello Chris: 1. Hypertension is defined as a systolic blood pressure of ≥140 mmHg or a diastolic blood pressure of ≥90 mmHg. However, it must be measured at least three times within two weeks, and the measurements should be taken under conditions of no stress (such as tension, an...

[Read More] Understanding Anxiety and Its Impact on Blood Pressure: A Guide


Understanding the Link Between Hypertension and Panic Disorders

Hello Doctor, I experienced my first panic attack due to a cold that triggered my blood pressure to rise to 180, which had never been that high before. After seeing the doctor and resting, I couldn't sleep and kept thinking about a neighbor who had high blood pressure over 2...


Dr. Li Zhengfeng reply Psychiatry
Hello: First, thank you for your letter. Hypertension is often asymptomatic. To confirm a diagnosis of hypertension, blood pressure must be measured in a calm state, and it should be elevated to make a definitive diagnosis. Patients with panic disorder often experience elevated b...

[Read More] Understanding the Link Between Hypertension and Panic Disorders


Related FAQ