Infection with human papillomavirus (HPV)
Due to abnormal results from the Pap smear (7-CIN1), further biopsy and HPV testing were conducted.
The biopsy results indicated CIN1; the high-risk HPV test was positive (detecting three or more types of the virus), while the low-risk HPV test was negative.
I would like to ask the doctor:
1.
I found information stating that 60% of people can clear HPV through their immune system.
Does this mean that there is no virus present in the body, or that the viral load has decreased to a level that is no longer infectious or pathogenic? Will I become an HPV carrier in the future?
2.
Is it possible that having a weaker immune system makes one more susceptible to simultaneously contracting multiple types of HPV viruses?
3.
Persistent infection with the virus increases the risk of cancer.
What does persistent infection mean?
4.
Since other high-risk HPV types (such as 16 and 18) were not detected, would you still recommend receiving the HPV vaccine? If vaccination is advisable, when would be the best time to receive it?
5.
Given my current situation, the doctor recommends improving my health to boost my immune system and continuing to monitor (with a Pap smear in three months).
Should I also have an HPV test done at that time, or how often should HPV testing be conducted? Thank you.
Niming, 30~39 year old female. Ask Date: 2018/05/23
Dr. Zhang Kunmin reply Obstetrics and Gynecology
Hello, the response to your inquiry is as follows:
1.
About 75% of individuals with HPV infection that progresses to CIN I can revert to normal cells without the virus.
2.
This situation can occur.
3.
This refers to the persistent presence of high-risk HPV and the progression of cellular lesions from CIN I to II to III, ultimately evolving into invasive cancer.
4.
If an individual has already been infected with certain types of human papillomavirus (there are over 200 types), receiving the HPV vaccine afterward will not prevent or treat diseases caused by those already infected HPV types; it can only prevent other types.
If the original virus type has cleared, then prevention is possible.
5.
It is recommended to check for HPV again after one year.
Wishing you peace and health,
Dr.
Zhang
Reply Date: 2018/05/23
More Info
Understanding HPV Infection: Key Questions and Insights for Women’s Health
Human Papillomavirus (HPV) is a common sexually transmitted infection that can lead to various health issues, including cervical cancer and other anogenital cancers. Your questions reflect a deep concern for your health and a desire to understand HPV better, especially in light of your recent medical findings. Let’s address your queries one by one.
1. Self-Immunity and HPV: When it is stated that about 60% of individuals can clear HPV through their immune system, it means that the body has successfully eliminated the virus to the point where it is no longer detectable. This does not necessarily mean that the virus is completely gone from the body; rather, it indicates that the viral load is low enough that it does not pose a risk of transmission or disease. However, it is possible to be a carrier of HPV without showing symptoms or having an active infection. Therefore, even if you clear the virus, there is a potential risk of being a carrier, especially if you have been exposed to multiple strains.
2. Immune Response and Multiple Infections: It is plausible that individuals with a weaker immune system may be more susceptible to multiple HPV infections. A robust immune response is crucial for controlling and clearing infections. Factors such as stress, poor nutrition, and underlying health conditions can compromise immune function, making it easier for the virus to establish an infection.
3. Persistent Infection and Cancer Risk: Persistent HPV infection refers to the continued presence of the virus in the body over time, which can lead to cellular changes and increase the risk of developing cancer. The risk of cervical cancer is particularly associated with high-risk HPV types, especially HPV 16 and 18. If the virus remains in the body for several years without being cleared, it can lead to precancerous lesions and eventually cancer.
4. Vaccination Recommendations: Even if you have tested positive for certain high-risk HPV types, vaccination is still recommended. The HPV vaccine can protect against additional strains of the virus that you may not have been exposed to yet. It is generally advised to receive the vaccine before becoming sexually active or before any potential exposure to HPV. If you are considering vaccination, it is best to consult with your healthcare provider about the timing, especially in relation to your current health status and any ongoing treatments.
5. Follow-Up Testing: Your doctor’s recommendation to improve your health and boost your immune system is crucial. Regarding follow-up testing, it is generally advisable to conduct HPV testing alongside Pap smears, especially if there are abnormal results. The timing for follow-up HPV testing can vary; typically, it is recommended to repeat testing every 6 to 12 months, depending on your individual risk factors and the results of your previous tests. Your healthcare provider will guide you on the appropriate schedule based on your specific situation.
In summary, understanding HPV and its implications for your health is essential. Regular screenings, maintaining a healthy lifestyle, and considering vaccination are all important steps in managing your risk. Always consult with your healthcare provider for personalized advice and recommendations tailored to your health needs. Your proactive approach to understanding HPV is commendable and will serve you well in managing your health moving forward.
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