Can Hypertension Medications Be Safe During Breastfeeding? - Pharmacology

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Can antihypertensive medications be taken while breastfeeding?


Due to having preeclampsia during pregnancy, the obstetrician prescribed antihypertensive medication, Tansulosin.
After discharge, following the doctor's advice, I visited a cardiologist and informed them about breastfeeding.
They prescribed two medications to be taken once daily: Nifedipine 30mg (Adalat) and Urosin 50mg (Urosin coated tablets).
After taking these medications, I experienced headaches and dizziness.
My blood pressure in the morning was 138/98, and after taking the medication at noon, it dropped to 106/82 in the afternoon.
I would like to know if this is a normal reaction and whether it is safe to continue breastfeeding while taking these two medications.
Thank you.

Peng, 30~39 year old female. Ask Date: 2018/05/26

Dr. Chen Yuemei reply Pharmacology


Hello: 1.
After reviewing your medications, (1) Nifedipine 30mg is safe to use during breastfeeding and poses minimal risk to the infant; (2) UROSIN 50MG (active ingredient: Atenolol) should be avoided during breastfeeding, as the risk to the infant cannot be excluded.
2.
The symptoms of headache and dizziness you experienced after taking the medication are likely due to a sudden drop in blood pressure.
It is recommended that you return to your doctor to inform them of your condition and adjust your medication accordingly.

Reply Date: 2018/05/26

More Info


When it comes to managing hypertension during breastfeeding, it is crucial to consider both the safety of the medications for the nursing infant and the mother's health. In your case, you are taking Nifedipine and Urosin, which are commonly prescribed for hypertension.


Safety of Hypertension Medications During Breastfeeding
1. Nifedipine: This medication is a calcium channel blocker that helps to lower blood pressure by relaxing the blood vessels. Studies indicate that Nifedipine is generally considered safe during breastfeeding. While it does pass into breast milk, the amounts are usually low and unlikely to affect a nursing infant adversely. However, it is always best to monitor the infant for any unusual symptoms, especially if the mother experiences side effects.

2. Urosin (also known as Urapidil): This medication is an antihypertensive agent that works by blocking alpha-1 adrenergic receptors, leading to vasodilation and reduced blood pressure. Similar to Nifedipine, Urosin is also considered safe for breastfeeding mothers. The amount that transfers into breast milk is minimal, and it is not expected to cause harm to the infant.


Side Effects and Blood Pressure Fluctuations
You mentioned experiencing headaches and dizziness after taking these medications, which can be common side effects of antihypertensive drugs. It is important to report these symptoms to your healthcare provider, as they may need to adjust your medication or dosage.
The fluctuation in blood pressure you observed (from 138/98 in the morning to 106/82 in the afternoon) is not unusual when starting a new antihypertensive regimen. Blood pressure can vary throughout the day due to various factors, including medication timing, hydration status, and stress levels. It is essential to monitor your blood pressure regularly and keep your healthcare provider informed of any significant changes or persistent symptoms.


Recommendations
1. Continue Breastfeeding: Given the safety profile of Nifedipine and Urosin, you can continue breastfeeding while on these medications. However, always consult with your healthcare provider regarding any concerns you may have.

2. Monitor Side Effects: Keep track of any side effects you experience and discuss them with your doctor. If headaches and dizziness persist, your doctor may consider adjusting your medication.

3. Regular Check-ups: Regular follow-ups with your healthcare provider are essential to ensure that your blood pressure is well-controlled and that the medications are not adversely affecting your health or breastfeeding.

4. Lifestyle Modifications: In addition to medication, consider lifestyle changes that can help manage hypertension, such as a balanced diet, regular exercise, and stress management techniques.


Conclusion
In summary, both Nifedipine and Urosin are generally safe for breastfeeding mothers. While you may experience some side effects, it is important to communicate these with your healthcare provider to ensure that your treatment plan is effective and safe for both you and your baby. Regular monitoring and open communication with your healthcare team will help manage your hypertension effectively while allowing you to continue breastfeeding.

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