Is It Safe to Breastfeed While Taking Hypertension Medications? - Pediatrics

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Hypertension medications and breastfeeding?


Hello doctor, I had an emergency cesarean section at 37 weeks due to hypertension, and my baby was born weighing only 2170 grams and forgot to breathe, so he is currently in the neonatal intensive care unit.
I would like to ask if the medications prescribed to me—amlodipine 5 mg, acetaminophen 500 mg, labetalol 200 mg, and hydralazine HCl 10 mg—are safe for breastfeeding and if they pose any risk to my baby.
I am very concerned, thank you, doctor.

Lingling, 30~39 year old female. Ask Date: 2012/12/13

Dr. Xiao Kaiwen reply Pediatrics


Pharmaceutical companies do not conduct studies on the secretion or quantity of drugs in breast milk for every medication they develop (in fact, this is rarely done, as it is not a requirement under the regulations for new drug development).
I believe that the concentration of drugs in breast milk is generally low; in principle, older medications tend to be safer, and single-agent medications are usually safer than combination therapies, although this is not absolute.
Ultimately, the focus should be on controlling your medical condition.
It is best to consult with the physician who prescribed your medication and the pediatrician for your newborn.

Reply Date: 2012/12/13

More Info


Breastfeeding while taking hypertension medications is a concern for many new mothers, especially when the baby is premature or has health issues. In your case, you are taking Amlodipine, Minophen (likely a typo for acetaminophen), Labetalol, and Hydralazine. Let's break down the safety of these medications during breastfeeding.

1. Amlodipine: This medication is a calcium channel blocker commonly used to treat high blood pressure. Studies have shown that Amlodipine is excreted in breast milk in small amounts. However, the levels are considered low enough that it is generally regarded as safe for breastfeeding mothers. The American Academy of Pediatrics classifies Amlodipine as compatible with breastfeeding, meaning it is unlikely to cause harm to the infant.

2. Minophen (Acetaminophen): Acetaminophen is widely used for pain relief and fever reduction. It is also considered safe during breastfeeding. It passes into breast milk in very small amounts, and it is commonly recommended for nursing mothers.

3. Labetalol: This medication is often prescribed for managing high blood pressure, especially in pregnant and postpartum women. Labetalol is also excreted in breast milk, but similar to Amlodipine, the amounts are minimal. It is generally considered safe for breastfeeding mothers, and it is often used in this population without significant concerns.

4. Hydralazine: This medication is used for hypertension and is also considered safe during breastfeeding. It is excreted in breast milk, but the levels are low, and it has been used in breastfeeding mothers without reported adverse effects on the infant.


General Considerations
While the medications you are taking are generally considered safe for breastfeeding, it is crucial to monitor your baby for any unusual symptoms, especially since your baby was born prematurely and is currently in the neonatal intensive care unit (NICU). Premature infants can be more sensitive to medications, so close observation is warranted.


Recommendations
1. Consult Your Pediatrician: Since your baby is in the NICU, it is essential to discuss your medications with the pediatrician or the neonatologist caring for your baby. They can provide specific guidance based on your baby's health status and any potential risks.

2. Monitor for Side Effects: Keep an eye on your baby for any signs of adverse reactions, such as unusual lethargy, feeding difficulties, or any other concerning symptoms. If you notice anything unusual, contact your healthcare provider immediately.

3. Stay Informed: Continue to educate yourself about the medications you are taking and their effects on breastfeeding. Your healthcare provider can help clarify any doubts and provide reassurance.

4. Consider Alternatives if Necessary: If there are concerns about the safety of your medications, your healthcare provider may consider alternative treatments that are known to be safer during breastfeeding.

In conclusion, while the medications you are taking for hypertension are generally considered safe for breastfeeding, it is essential to maintain open communication with your healthcare team and monitor your baby's health closely. Your well-being and your baby's health are of utmost importance, and your healthcare providers are there to support you through this process.

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