Chronic Kidney Disease and Vitamin B: What You Need to Know - Internal Medicine

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Chronic Kidney Disease and Vitamin B Complex


Hello Dr.
Wu Chi-Yu: I am a patient with chronic kidney disease.
In my recent blood test report, my serum creatinine is 2.73, blood urea nitrogen is 33, glomerular filtration rate is 26.6, phosphorus is 5.4, and uric acid is 8.1.
All other values, including total protein, albumin, calcium, potassium, and sodium, are within normal ranges.
I would like to ask if I can take SS Aisfit-DX (B vitamins), or if you have any recommendations for the daily intake of B vitamins.
Below are the ingredient contents per tablet of SS Aisfit-DX (B vitamins): Bisbentamine 33.33 mg (vitamin B1 derivative), vitamin B6 33.33 mg, vitamin B12 500 μg, vitamin E 34.53 mg, niacin 10 mg.
Thank you, Dr.
Wu Chi-Yu, for taking the time to respond.

Mr. Lin, 40~49 year old female. Ask Date: 2018/05/31

Dr. Wu Jiyu reply Internal Medicine


According to the current guidelines provided by international journals:
Vitamin B1: 1.5 mg/day
Vitamin B6: 5 mg/day
Vitamin B12: 2-3 µg/day
Vitamin E: Additional supplementation is not recommended
Niacin: 14-20 mg/day
If you are concerned about insufficient dietary intake and need nutritional supplementation, please consult a hospital nutritionist for further advice.
Thank you for your inquiry.
The Nephrology Department of Changhua Hospital cares about you.

Reply Date: 2018/05/31

More Info


Chronic Kidney Disease (CKD) presents unique challenges when it comes to dietary and nutritional considerations, particularly regarding vitamin supplementation. As a patient with CKD, understanding the implications of taking vitamin B supplements, such as SS愛斯飛特-DX (B complex), is crucial for managing your health effectively.


Understanding Vitamin B and CKD
Vitamin B complex includes several essential vitamins, such as B1 (thiamine), B6 (pyridoxine), B12 (cobalamin), niacin (B3), and others. These vitamins play vital roles in energy metabolism, red blood cell production, and neurological function. However, patients with CKD must be cautious with supplementation due to potential impacts on kidney function and overall health.


Safety of Vitamin B Supplementation in CKD
1. Kidney Function and Vitamin B: In patients with CKD, the kidneys' ability to filter waste products and excess substances from the blood is compromised. This can lead to an accumulation of certain vitamins and minerals, particularly those that are water-soluble, like the B vitamins. However, the B vitamins are generally considered safe for supplementation in CKD patients when taken in appropriate doses.

2. Recommended Dosages: According to current guidelines, the recommended daily allowances (RDAs) for B vitamins vary:
- Vitamin B1 (Thiamine): 1.5 mg/day
- Vitamin B6 (Pyridoxine): 5 mg/day
- Vitamin B12 (Cobalamin): 2-3 µg/day
- Niacin (B3): 14-20 mg/day
- Vitamin E: Not typically recommended for supplementation unless there is a deficiency.

Your specific product, SS愛斯飛特-DX, contains higher amounts of some B vitamins, particularly B12 (2500 µg), which is significantly above the recommended daily intake. While B12 is generally safe, excessive amounts may not provide additional benefits and could lead to unnecessary costs or complications.

3. Monitoring and Adjustments: Given your current kidney function (eGFR of 26.6), it is essential to monitor your vitamin levels regularly. Your healthcare provider may recommend periodic blood tests to assess your vitamin B levels and adjust your supplementation accordingly.
4. Consulting Healthcare Providers: Always consult with your nephrologist or a registered dietitian before starting any new supplement, especially if you have CKD. They can provide personalized recommendations based on your overall health status, dietary intake, and specific kidney function.


Dietary Considerations
In addition to supplementation, dietary management is critical for CKD patients. A balanced diet that includes adequate protein, while being mindful of phosphorus and potassium intake, is essential. Foods rich in B vitamins, such as whole grains, legumes, nuts, and seeds, can be beneficial. However, be cautious with high-potassium foods if your potassium levels are elevated.


Conclusion
In summary, while vitamin B supplementation can be beneficial for individuals with CKD, it is crucial to approach it with caution. The potential for vitamin accumulation and the unique dietary needs of CKD patients necessitate careful monitoring and consultation with healthcare professionals. Always prioritize a balanced diet and follow your healthcare provider's recommendations regarding supplementation to ensure optimal health outcomes.

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