Muscle Twitching: When Medication Fails and Anxiety Persists - Neurology

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Involuntary muscle twitching, with no improvement after medication?


Hello Doctor, I previously inquired about #36811.
I went to see a doctor and underwent nerve conduction studies and blood tests, which were normal.
I was diagnosed with iron deficiency anemia, and the doctor prescribed Lyrica (pregabalin) and iron supplements.
He mentioned that if I feel very uncomfortable, I can take the medication.
During the first week of taking it, I noticed significant improvement; my muscles weren't twitching excessively, and during my days off, they didn't twitch at all.
However, I stopped taking the medication after the second week, and by the third week, my muscles started twitching involuntarily again.
Even after taking the medication, the next day they continued to twitch, and I feel like there hasn't been any improvement.
Also, does Lyrica cause dry mouth as a side effect? Will taking this medication long-term put a significant burden on my body? I am on a dosage of 0.5 mg; why is it prescribed this way? I tend to get anxious, especially when I have to rush to complete tasks at work, which causes my muscles to twitch even more.
The doctor advised me to relax and not to be overly tense, but my muscles keep twitching everywhere, and after a while, it leads to panic.
I am unsure when this will get better.

Vivi, 30~39 year old female. Ask Date: 2018/09/07

Dr. Jiang Junyi reply Neurology


Hello: Regarding your question about whether Rivotril (clonazepam) can cause dry mouth as a side effect, it is quite common, but it is generally not as severe compared to other medications.
This medication belongs to the class of sedative-hypnotics, which may have the potential for dependence.
Your current dosage is low (0.5-20 mg), and since the effects take 1-2 hours to manifest, the risk of addiction is very low.
Consider how smokers feel the effects within 5-7 minutes, making it harder to quit.
Since you tend to feel anxious and sometimes rush to complete tasks at work, it can lead to increased muscle tension.
Your doctor has advised you to relax and not to be overly stressed, but persistent muscle tension can lead to panic.
It’s uncertain when this will improve.
I recommend avoiding excessive caffeine intake, taking breaks from Rivotril on weekends, and supplementing with B vitamins, as these methods can aid in nerve recovery.
It would be beneficial for you to consult a neurologist for further discussion and treatment.
Wishing you good health and peace.
Dr.
Jiang from the Neurology Department cares about you.

Reply Date: 2018/09/07

More Info


Muscle twitching, also known as fasciculation, can be a distressing experience, especially when it persists despite medication and is compounded by anxiety. Your situation highlights a common challenge faced by many individuals dealing with both physical symptoms and mental health issues.
From your description, it seems that you have undergone various medical evaluations, including nerve conduction studies and blood tests, which returned normal results except for iron deficiency anemia. This is an important first step in ruling out serious underlying conditions. The fact that your doctor prescribed an anticonvulsant medication (likely referring to a drug like Gabapentin or Pregabalin) and iron supplements suggests that they are addressing both the muscle twitching and the anemia.

You mentioned that you experienced significant improvement during the first week of medication but noticed a return of symptoms after discontinuing the medication. This pattern is not uncommon; muscle twitching can be influenced by several factors, including stress, anxiety, and even lifestyle changes. The fact that you noticed a reduction in twitching during your time off work suggests that stress may play a significant role in your symptoms.

Regarding your concerns about the side effects of the medication, it is true that some anticonvulsants can cause dry mouth, fatigue, and other side effects. However, the specific side effects can vary depending on the medication. If you are taking a low dose (0.5 mg), it is generally considered a safe starting point, but long-term use should always be monitored by your healthcare provider to avoid potential complications.

The relationship between anxiety and muscle twitching is well-documented. Anxiety can lead to increased muscle tension, which may exacerbate twitching. Additionally, the cycle of anxiety can create a feedback loop where the twitching itself causes further anxiety, leading to more twitching. This is a common phenomenon in anxiety disorders, where physical symptoms can amplify psychological distress.

To manage your symptoms effectively, consider the following strategies:
1. Medication Management: If you find that the medication is not providing the relief you need, discuss this with your doctor. They may consider adjusting the dosage or trying a different medication that may be more effective for your symptoms.

2. Stress Reduction Techniques: Incorporate relaxation techniques into your daily routine. Practices such as mindfulness meditation, deep breathing exercises, yoga, or tai chi can help reduce overall anxiety levels and may alleviate muscle tension.

3. Physical Activity: Regular exercise can be a powerful tool for managing anxiety and muscle tension. It helps release endorphins, which can improve mood and reduce stress.

4. Nutrition and Hydration: Ensure you are eating a balanced diet rich in vitamins and minerals, particularly iron, to address your anemia. Staying well-hydrated can also help reduce muscle cramps and twitching.

5. Sleep Hygiene: Prioritize good sleep habits, as poor sleep can exacerbate anxiety and muscle twitching. Aim for a consistent sleep schedule and create a restful environment.

6. Therapy: Consider seeking therapy, such as cognitive-behavioral therapy (CBT), which can help you develop coping strategies for anxiety and reduce the impact of physical symptoms on your mental health.

7. Support Groups: Engaging with others who experience similar symptoms can provide emotional support and practical advice. Online forums or local support groups can be beneficial.

In conclusion, while muscle twitching can be frustrating and anxiety-provoking, understanding the interplay between your physical and mental health can empower you to take proactive steps toward managing your symptoms. Regular communication with your healthcare provider is crucial, as they can help tailor a treatment plan that addresses both your physical and psychological needs. Remember, recovery is often a gradual process, and it’s important to be patient with yourself as you navigate this journey.

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