Is a Single Injection Enough to Cure Gonorrhea? Symptoms and Treatment - Urology

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Will a single injection cure it? What does it mean when the body feels cold?


Hello Doctor, I would like to ask you the following questions:
1) Is gonorrhea cured with just one injection? When I visited the urology department, the doctor told me that gonorrhea can be treated with a single injection, and the antibiotics and other medications prescribed were for treating chlamydia.
Is this correct?
2) Recently, I experienced chills and a headache, thinking it was caused by a cold, so I went to see an ENT specialist.
However, the next day I noticed yellow discharge from the urethra, which led me to visit the urology department where I was diagnosed with gonorrhea.
I would like to ask the doctor if chills and headaches are symptoms associated with gonorrhea, or is there a possibility of having another sexually transmitted infection? Or could it just be a simple cold?

Li, 20~29 year old female. Ask Date: 2018/12/24

Dr. Du Shixi reply Urology


Hello: 1) It is possible, but you should still pay attention to whether there is any discharge from the urethra; clinical symptoms are more important.
Engaging in unsafe sexual practices is highly discouraged.
2) Are chills and headaches symptoms that can occur with gonorrhea? --> It can only be said that it is possible, and there is a chance of being infected with other sexually transmitted infections (STIs).
--> If you have engaged in unsafe sexual practices, depending on the STI status of your partner, you may be at risk of transmission.
Wishing you good health.

Reply Date: 2018/12/24

More Info


Gonorrhea, caused by the bacterium Neisseria gonorrhoeae, is a sexually transmitted infection (STI) that can affect various parts of the body, including the urethra, throat, and rectum. The treatment for gonorrhea typically involves antibiotics, and the effectiveness of a single injection can vary based on several factors.

1. Is a Single Injection Enough to Cure Gonorrhea?
The standard treatment for uncomplicated gonorrhea is a single dose of an injectable antibiotic, usually ceftriaxone. This is often combined with another antibiotic, such as azithromycin, to cover potential co-infections, particularly with Chlamydia trachomatis, which is a common co-infection with gonorrhea. Therefore, while a single injection of ceftriaxone can effectively cure gonorrhea, it is essential to follow the prescribed treatment regimen, which may include additional medications for other infections.

2. Understanding Symptoms:
Gonorrhea can present with various symptoms, but many individuals may be asymptomatic. Common symptoms in men include a burning sensation during urination, yellow or green discharge from the penis, and swollen testicles. In women, symptoms can include painful urination, increased vaginal discharge, and bleeding between periods. However, systemic symptoms such as fever, chills, and headaches are not typical for gonorrhea itself.
In your case, experiencing chills and headaches could be indicative of a different infection or a systemic response to the gonorrhea infection. It is also possible that these symptoms could be related to another sexually transmitted infection (STI) or even a viral illness like the flu. The presence of yellow discharge from the urethra is a more direct indicator of gonorrhea, but the accompanying systemic symptoms warrant further investigation.

3. Potential for Other Infections:
Given your symptoms, it is crucial to consider the possibility of other STIs. Many STIs can present with overlapping symptoms, and co-infections are common. For instance, Chlamydia is often asymptomatic but can cause similar symptoms to gonorrhea. Other infections, such as trichomoniasis or even non-STI-related infections, could also be responsible for your symptoms.

4. Next Steps:
It is essential to follow up with your healthcare provider for a comprehensive evaluation. They may recommend additional tests to rule out other STIs or infections. It is also important to inform any sexual partners about your diagnosis so they can seek treatment as well, as STIs can easily be transmitted between partners.

In summary, while a single injection of ceftriaxone is typically effective for treating gonorrhea, it is crucial to adhere to the full treatment plan and consider the possibility of co-infections. Your systemic symptoms should be evaluated further to determine their cause, and ongoing communication with your healthcare provider is key to managing your health effectively.

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