Fever After Vaccination: A Parent's Guide - Pediatrics

Share to:

Vaccine issues?


Hello, doctor.
My baby is 6 months old and received the pentavalent vaccine, hepatitis B vaccine, and oral rotavirus vaccine last Friday.
Two days later, on Monday night, he developed a fever.
We took him to the clinic, and they said that since it was the third day, it was unrelated to the vaccines and advised us to continue monitoring.
However, the fever has been recurring, and he has no cold symptoms, but his appetite is still good.
He only gets relief from the fever with antipyretics.
We took him back for another visit, and they tested his urine, ruling out a urinary tract infection, and again advised us to monitor.
They mentioned it could be roseola.
The fever lasted until Thursday and has since subsided, but he has not developed any rash, so we can confirm it is not roseola.
I would like to ask the doctor if this is related to the vaccines.
He did not have a fever after the first two doses, but this time he developed a fever on the third day after the third dose.
If it is not related to the vaccines, what could this be? Could it be due to receiving two vaccines at once? The clinic only told us to monitor and that as long as he is not feverish, it is fine.
However, I am puzzled as to why he had a fever for four days without any cold symptoms or roseola.
Is this situation common? Thank you for your response, doctor.

Pei, 20~29 year old female. Ask Date: 2019/01/12

Dr. Xiao Kaiwen reply Pediatrics


The situation with your child is likely not due to a fever caused by the vaccine, as fever from the pentavalent vaccine and hepatitis B vaccine (which can be administered simultaneously) typically occurs within 24 hours post-vaccination and does not last longer than 48 hours.
Most fevers in infants are due to viral infections, and sometimes there may not be obvious external symptoms.
As their immune system gradually develops, the fever will subside.
Additionally, it is important to clarify a concept: the presence of a rash may indicate roseola, but the absence of a rash does not definitively rule it out.
Sometimes, the infant's immune system may be functioning well enough that the fever resolves without the appearance of a rash.

Reply Date: 2019/01/12

More Info


When it comes to managing fever after vaccination in infants, it is essential for parents to understand the typical responses to vaccines and when to seek medical attention. Vaccination is a crucial part of preventive healthcare, and while it can lead to mild side effects, understanding these reactions can help alleviate parental concerns.

In your case, your six-month-old baby received multiple vaccinations, including the pentavalent vaccine (which typically protects against diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b), hepatitis B, and oral rotavirus. It is not uncommon for infants to develop a fever after vaccination, particularly after receiving multiple vaccines in one visit. The fever usually indicates that the immune system is responding to the vaccine, which is a normal and expected reaction.

Typically, fever after vaccination can occur within a few days, often peaking around 24 to 48 hours post-vaccination. The fever is usually low-grade (below 102°F or 39°C) and resolves within a couple of days. However, in some cases, as you've experienced, the fever can persist longer than expected. The fact that your baby has been feverish for several days, yet shows no signs of respiratory illness or other symptoms, can be concerning.

Given that your baby has been experiencing fever for four days without any other symptoms, it is essential to consider other potential causes. While the healthcare provider you consulted suggested that the fever is not related to the vaccines, it is still important to monitor for any additional symptoms. The absence of respiratory symptoms and the good appetite are positive signs, but persistent fever can sometimes indicate other underlying issues, such as a viral infection unrelated to the vaccines, or, in rare cases, a reaction to the vaccine itself.

Here are some steps you can take as a parent:
1. Monitor Symptoms: Keep a close watch on your baby's temperature and any other symptoms that may arise. Note any changes in behavior, feeding, or activity levels.

2. Hydration: Ensure your baby stays well-hydrated. Fever can lead to dehydration, so offering fluids is crucial.

3. Fever Management: Continue to use fever-reducing medications like acetaminophen (Tylenol) as recommended by your healthcare provider. Ensure you follow the dosing guidelines based on your baby's weight and age.

4. Follow-Up: If the fever persists beyond a few days or if your baby develops new symptoms (such as rash, irritability, or decreased responsiveness), it is advisable to follow up with your pediatrician. They may want to conduct further evaluations to rule out any infections or other conditions.

5. Vaccination Schedule: Discuss with your pediatrician about the vaccination schedule and any concerns regarding the timing of multiple vaccines. Sometimes, spacing out vaccines can reduce the likelihood of side effects, although this is not always necessary.

6. Educate Yourself: Familiarize yourself with common vaccine side effects and when they typically occur. Resources from reputable health organizations can provide valuable information.

In conclusion, while it is common for infants to experience fever after vaccinations, persistent fever that lasts several days warrants further observation and possibly additional medical evaluation. Keeping an open line of communication with your healthcare provider is key to ensuring your child's health and well-being.

Similar Q&A

Fever After Vaccination: What Parents Should Know About Infant Reactions

Hello, doctor! My baby is two months old. He received the 13-valent pneumococcal vaccine and the pentavalent vaccine the morning before yesterday, and he started having a fever last night, with a maximum temperature of 39 degrees Celsius. Could this be related to the vaccines, or...


Dr. Xiao Kaiwen reply Pediatrics
If fever occurs after administering the pentavalent vaccine and the 13-valent pneumococcal vaccine, it typically happens within 24 hours of vaccination and usually does not last more than 24 hours. Therefore, your child may have another illness causing the fever, and it is recomm...

[Read More] Fever After Vaccination: What Parents Should Know About Infant Reactions


Is Your 18-Month-Old's Fever Linked to Recent Vaccinations?

On Thursday, the child received the second dose of the hepatitis A vaccine and the fourth dose of the pentavalent vaccine. After the previous vaccinations, there were no fever reactions. However, on Saturday morning, the child's ear temperature was 38 degrees Celsius, and th...


Dr. He Zongxian reply Pediatrics
Hello, experiencing a fever two days after receiving an inactivated vaccine is not a typical post-vaccination reaction. If the fever persists, it is recommended that you take your child to a pediatric medical facility for evaluation, as there may be a risk of urinary tract infect...

[Read More] Is Your 18-Month-Old's Fever Linked to Recent Vaccinations?


Should I See a Doctor After My Child's Vaccination Reactions?

My child is over 7 months old. After receiving the pneumococcal vaccine and the DTaP (diphtheria, tetanus, and pertussis) combination vaccine last Friday, they have had a slight fever and developed a rash near the injection site. Should I take them to see a doctor?


Dr. Xiao Kaiwen reply Pediatrics
The symptoms you described do not resemble the side effects typically associated with vaccination. Fever after vaccination usually does not last more than 24 hours, and rashes near the injection site are not common. It is advisable to consult a pediatrician for further evaluation...

[Read More] Should I See a Doctor After My Child's Vaccination Reactions?


Understanding Fever, Flu Vaccines, and Hand Hygiene in Young Children

Hello Doctor: My little one (2 years and 1 month) had a fever for 2 days starting on September 1, with a maximum temperature of 38.6°C (rectal). During these two days, there was also some diarrhea. Overall, their health has been good, and they have been doing well these past few ...


Dr. Xiao Kaiwen reply Pediatrics
1. Fever in children is mostly caused by infections, and diarrhea can be explained as an infection due to gastroenteritis. 2. If the body temperature has returned to normal and energy and appetite have improved, the child should be considered recovered; however, continued obser...

[Read More] Understanding Fever, Flu Vaccines, and Hand Hygiene in Young Children


Related FAQ

Fever

(Pediatrics)

Vaccination Injection

(Pediatrics)

Enterovirus

(Pediatrics)

Pneumococcal Vaccine

(Pediatrics)

Purpura

(Pediatrics)

Fever

(Influenza)

Fever

(Family Medicine)

Bedwetting

(Pediatrics)

Pediatric Vomiting

(Pediatrics)

Medical Report

(Pediatrics)