and Managing Anal Warts: Treatment Options and Concerns - Urology

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Cauliflower issue


Hello Doctor, last year I went to a large hospital for an examination and found cauliflower-like growths around my anus (there are also a few similar spots in my intimate area).
The gynecologist suggested using podophyllotoxin for treatment, which reduced the size but did not completely eliminate them.
I also sought traditional Chinese medicine to remove the warts, but it seems they were not completely eradicated.
I switched to another brand of ointment (Anyou cream) and continued applying it.
During the treatment period, I also received the HPV vaccine, but recently I experienced itching in my intimate area and was concerned about a recurrence of the warts, so I visited the gynecologist again.
The doctor said it was not warts, but to be sure, I underwent an HPV Pap smear to check if it was indeed warts.
Recently, I switched back to using podophyllotoxin around the anus, and the area around the anus and the lesions have become very itchy, to the point where I need to scratch to relieve the itch (initially, when I used podophyllotoxin for a long time, I did not experience this discomfort).
I scratched the area, and it seems to have become slightly broken and swollen.
Because the itching is unbearable and uncomfortable, I stopped applying the medication for a few days since my menstrual period started.
Additionally, using cooling pads helps alleviate the itchiness.
However, at night or in the middle of the night, the area around the anus becomes very itchy again.
The HPV test results came back normal and negative, but there are still wart-like growths around the anus.
The doctor mentioned that they resemble polyps but advised me to continue applying the ointment for another month, using it one day and stopping the next.
However, the itching persists, and the area around the anus is still swollen and broken.
Should I continue applying the medication, or should I treat the broken skin as well? If I want to freeze the anal warts, can I go to the gynecology department for treatment? Thank you.

W, 20~29 year old female. Ask Date: 2019/06/29

Dr. Cai Zhuorong reply Urology


For uncertain diagnoses, surgical excision and pathological examination may be considered.
Lesions around the anus are recommended to be evaluated by a colorectal surgeon.

Reply Date: 2019/06/29

More Info


Managing anal warts, also known as genital warts, can be a challenging process, particularly when it comes to treatment options and addressing associated symptoms such as itching and discomfort. It’s important to understand the nature of these warts, their treatment options, and how to manage any side effects or complications that may arise during treatment.

Anal warts are caused by certain strains of the human papillomavirus (HPV). They can appear as small, flesh-colored or gray growths and may resemble cauliflower. While you mentioned that you have undergone treatment with topical medications like phenol and have received the HPV vaccine, it’s not uncommon for warts to persist or recur after treatment. The fact that your HPV test came back negative is a positive sign, indicating that you do not have the high-risk strains of the virus that could lead to cancer, but it does not eliminate the presence of low-risk strains that cause warts.

In your case, the itching and irritation you are experiencing could be due to several factors. First, the topical treatments can sometimes cause skin irritation, especially if used for an extended period or if the skin is sensitive. The fact that you have noticed increased itching and redness, particularly after scratching, suggests that there may be a secondary irritation or even a mild infection occurring. It’s crucial to avoid scratching the area, as this can lead to further irritation and potential infection.

Given your symptoms, it would be advisable to consult your healthcare provider about the following:
1. Assessment of Skin Condition: Since you have developed redness and broken skin, it’s important to have this assessed by a healthcare professional. They can determine whether the irritation is due to the medication, an allergic reaction, or a secondary infection that may require different treatment.

2. Treatment Options: If the topical treatments are causing significant irritation, your doctor may suggest pausing the use of these medications until the skin heals. They may also consider alternative treatments, such as cryotherapy (freezing the warts), which can be effective for wart removal. This procedure can be performed in a gynecological or dermatological setting.

3. Managing Itching and Discomfort: In the meantime, to alleviate itching, you might consider using soothing topical treatments that are safe for sensitive areas, such as hydrocortisone cream (if recommended by your doctor) or over-the-counter anti-itch creams. Keeping the area clean and dry is also essential.

4. Follow-Up Care: Regular follow-up appointments are important to monitor the condition of the warts and any potential recurrence. If the warts do not respond to topical treatments, your doctor may recommend other options, including laser therapy or surgical removal.

5. HPV Vaccination: It’s good that you have received the HPV vaccine, as it can help protect against certain strains of the virus. However, it does not treat existing warts. Continuing to discuss vaccination options with your healthcare provider is important.

In summary, while topical treatments can be effective for managing anal warts, they can also lead to irritation and discomfort. It’s crucial to communicate openly with your healthcare provider about your symptoms and treatment response. They can provide tailored advice and alternative treatment options to help manage your condition effectively. Remember, patience and consistent follow-up care are key components in managing HPV-related conditions.

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