Anemia: Symptoms and Concerns in Oncology Patients - Oncology

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Dizziness and headache?


Hello Doctor: Recently, I had a health check at my company, and the results showed that my blood test was abnormal: Hb 9.7, Hct 32.1, MCV 69.4, MCH 20.9, MCHC 30.2, RDW 16.8, PLT 516.
Is this anemia considered severe? Thank you for taking the time to read my question.

Ya Ya, 40~49 year old female. Ask Date: 2019/06/30

Dr. Hu Ziren reply Oncology


It appears to be moderate iron deficiency anemia.
It is recommended to consult a hematologist for further evaluation.

Reply Date: 2019/06/30

More Info


Anemia is a common concern in oncology patients and can significantly impact their overall health and treatment outcomes. Based on the laboratory results you provided, it appears that you are experiencing a form of anemia, characterized by a low hemoglobin (Hb) level of 9.7 g/dL, a hematocrit (Hct) of 32.1%, and other indices indicating microcytic anemia (low mean corpuscular volume, or MCV, of 69.4 fL).

Understanding Your Results
1. Hemoglobin (Hb): Normal levels for men typically range from 13.8 to 17.2 g/dL and for women from 12.1 to 15.1 g/dL. Your Hb level of 9.7 g/dL is indeed low, indicating moderate to severe anemia.


2. Hematocrit (Hct): This measures the proportion of blood volume that is occupied by red blood cells. Normal ranges are approximately 38.3% to 48.6% for men and 35.5% to 44.9% for women. Your Hct of 32.1% is also below the normal range.

3. Mean Corpuscular Volume (MCV): This indicates the average size of red blood cells. A low MCV (like your 69.4 fL) suggests microcytic anemia, which is often due to iron deficiency or thalassemia.

4. Mean Corpuscular Hemoglobin (MCH) and Mean Corpuscular Hemoglobin Concentration (MCHC): These values further support the diagnosis of microcytic anemia, as both are low.

5. Red Cell Distribution Width (RDW): A high RDW (16.8%) indicates a variation in red blood cell size, which can be seen in various types of anemia, including iron deficiency.

6. Platelet Count (PLT): Your platelet count of 516 x 10^9/L is elevated, which can occur in response to anemia or other underlying conditions.


Symptoms of Anemia
Common symptoms of anemia include fatigue, weakness, pallor, shortness of breath, dizziness, and in severe cases, chest pain or heart palpitations. In oncology patients, these symptoms can be exacerbated by the cancer itself or the treatments they are undergoing, such as chemotherapy, which can further suppress bone marrow function and lead to additional anemia.


Concerns in Oncology Patients
In oncology patients, anemia can complicate treatment regimens. It can lead to dose reductions in chemotherapy, delays in treatment, and a decreased quality of life. Anemia can also increase the risk of complications, such as infections and cardiovascular issues, especially in patients with pre-existing conditions.


Recommendations
1. Consult Your Oncologist: It is crucial to discuss your results with your healthcare provider. They can help determine the underlying cause of your anemia, which may include iron deficiency, chronic disease, or bone marrow suppression due to cancer or its treatment.

2. Further Testing: Your doctor may recommend additional tests, such as iron studies (serum iron, ferritin, total iron-binding capacity), vitamin B12 and folate levels, and possibly a bone marrow biopsy if indicated.

3. Treatment Options: Depending on the cause of your anemia, treatment may include iron supplementation, vitamin B12 injections, erythropoiesis-stimulating agents (ESAs), or blood transfusions in severe cases.

4. Dietary Considerations: Incorporating iron-rich foods (like red meat, beans, lentils, and leafy greens) and foods high in vitamin C (which helps with iron absorption) can be beneficial.

5. Monitor Symptoms: Keep track of any symptoms you experience and report them to your healthcare team. This can help in adjusting your treatment plan accordingly.

In summary, your anemia is significant and warrants further investigation and management. Engaging with your healthcare team will be essential in addressing this issue effectively and ensuring that your overall treatment plan is optimized for your health and well-being.

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