Concerns About Medication Use During Pregnancy Preparation - Obstetrics and Gynecology

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Questions about medications for pregnancy preparation?


Hello, doctor.
I have issues with vaginitis and urethritis.
A few days ago, I visited a gynecologist who prescribed vaginal suppositories for me.
Additionally, I saw a urologist who noted inflammation and prescribed antibiotics, along with medication for my stomach, for a three-day course.
Most of the medications are classified as Category B, but one medication named "Fornil S.C.
tablets," which is classified as Category D, was included.
After taking these medications, I ovulated the next day.
My husband and I have been trying to conceive, as I initially went to see the doctor thinking I might not be pregnant.
However, I found online that some people report caution regarding medication use during the conception period, and now I'm worried about whether it could have any effects if I am pregnant.
Could you please help me with this?

a, 30~39 year old female. Ask Date: 2019/09/12

Dr. Huang Yiwen reply Obstetrics and Gynecology


Hello Miss: You don't need to worry too much about your situation.
Theoretically, a medication would need to affect the fetus at least two to four weeks after conception.
Since you are not even sure if you are pregnant yet, and your menstrual period has not even been missed, if you were to become pregnant this time, the medication would have already been metabolized, so there is no need for concern.

Reply Date: 2019/09/12

More Info


When preparing for pregnancy, it is crucial to be aware of the medications you are taking, as some can have potential risks to the developing fetus. Your concerns regarding the use of medications during this sensitive period are valid, especially considering the classification of the drugs you mentioned.

The FDA categorizes medications into five categories (A, B, C, D, and X) based on their potential risks during pregnancy. Category A is considered the safest, while Category X indicates that the drug is contraindicated in pregnancy due to evidence of fetal harm. Category D, which includes the medication "Fornil s.c. tablets" (or "福樂你糖衣錠"), indicates that there is positive evidence of human fetal risk, but the benefits of the drug may outweigh the risks in certain situations.

In your case, you mentioned that you were prescribed a vaginal suppository for vaginitis and antibiotics for a urinary tract infection (UTI), along with a stomach medication. If these medications are primarily classified as Category B, they are generally considered safe for use during pregnancy, as animal studies have not demonstrated any risk to the fetus. However, the presence of a Category D medication raises concerns.

The use of "Fornil" (which contains the active ingredient for the treatment of infections) during the conception period may pose risks, particularly if taken during the early stages of pregnancy when organogenesis (the formation of organs) occurs. This is a critical period where exposure to certain medications can lead to congenital anomalies.

Given that you are currently in your ovulation phase, it is essential to consider the timing of medication exposure. If conception occurs shortly after taking the medication, there may be a potential risk to the embryo. However, it is also important to note that not all medications classified as Category D will necessarily cause harm, and the actual risk can depend on various factors, including dosage, duration of use, and individual patient circumstances.

Here are some recommendations for you:
1. Consult Your Healthcare Provider: It is crucial to discuss your concerns with your obstetrician or a maternal-fetal medicine specialist. They can provide personalized advice based on your medical history and the specific medications you have taken.

2. Monitor for Symptoms: If you do conceive, keep an eye on any unusual symptoms or changes in your health. Early prenatal care is essential, so schedule an appointment as soon as you suspect you might be pregnant.

3. Consider Alternative Treatments: If you are actively trying to conceive, discuss with your healthcare provider the possibility of alternative treatments that may be safer during this period.

4. Stay Informed: Educate yourself about the medications you are prescribed, including their classifications and potential risks. This knowledge can empower you to make informed decisions about your health and pregnancy.

5. Focus on Overall Health: In addition to managing infections, focus on maintaining a healthy lifestyle, including a balanced diet, regular exercise, and avoiding harmful substances, as these factors can significantly impact fertility and pregnancy outcomes.

In conclusion, while your concerns about medication use during pregnancy preparation are valid, it is essential to approach the situation with a clear understanding and guidance from healthcare professionals. Open communication with your doctors will help ensure that you are making the best choices for your health and the health of your future baby.

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