Left-Sided Symptoms: Possible Immune System Issues - Internal Medicine

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Immune system issues?


Hello, doctor.
I am currently preparing for my college entrance exam, but I have been experiencing some unusual symptoms and would like to seek your reassurance.
I would like to ask why my symptoms are predominantly affecting the left side of my body.
For example: 1.
Recently, I had a severe case of pharyngitis, and the lymph nodes on the left side of my neck were noticeably larger and more painful than those on the right side.
2.
I have canker sores and tongue ulcers concentrated on the left side of my mouth, and the lymph nodes in my left neck are slightly painful (current symptoms).
3.
I only have acne on the left side of my face, while the right side is completely clear (current symptoms).
4.
I have a pimple in my left nostril (current symptoms).
For the past two to three months, my body temperature has been around 37.1 to 37.6 degrees Celsius.
I have been spending long hours in a cold air-conditioned environment for my retake classes, which makes me wonder if there is an abnormality in my left-side immune system.
I couldn't find relevant information online, and I hope you can provide some advice.
Thank you!

109, 10~19 year old female. Ask Date: 2019/12/04

Dr. Hong Yuanbin reply Internal Medicine


Hello: The effects of the immune system are generally systemic, with very few distinctions made between the left and right sides.
Therefore, the likelihood of a systemic immune response is relatively low.
However, the left-sided lymphadenopathy and some discomfort you described are likely due to a more pronounced infection in your left throat from pharyngitis.
It is expected that these symptoms will resolve as the pharyngitis improves.
Unless the symptoms persist for an extended period, further examination may be necessary.
Thank you for your inquiry.

Reply Date: 2019/12/04

More Info


It sounds like you are experiencing a range of concerning symptoms that are predominantly affecting the left side of your body. While it is understandable to be worried about these symptoms, it is important to approach the situation with a clear understanding of how the immune system works and the potential causes of your symptoms.

Firstly, the immune system operates as a complex network that responds to infections, injuries, and other threats to the body. It is generally not divided into left and right sides; rather, it functions as a whole. However, localized symptoms, such as those you are experiencing, can occur due to various reasons, including infections, inflammation, or even stress.

1. Lymph Node Swelling: The swelling of the lymph nodes on the left side of your neck, particularly in response to a throat infection, is a common immune response. Lymph nodes filter lymph fluid and help the body fight infections. If the left side is more swollen and painful, it could indicate that the infection is more pronounced on that side, which is not unusual. As your throat infection resolves, these symptoms should improve.

2. Mouth and Tongue Ulcers: The occurrence of ulcers in your mouth and on your tongue, particularly on the left side, could be related to several factors, including stress, nutritional deficiencies (such as vitamin B12, folate, or iron), or even localized infections. Stress, especially during exam preparation, can weaken your immune response and lead to such symptoms.

3. Acne and Skin Issues: The development of acne or skin lesions on the left side of your face and nose may not necessarily be linked to your immune system. Hormonal fluctuations, dietary factors, and skin care routines can all contribute to localized acne. It is also worth considering that stress can exacerbate skin conditions.

4. Persistent Low-Grade Fever: A consistent body temperature in the range of 37.1 to 37.6 degrees Celsius may indicate a low-grade fever, which can be associated with various conditions, including chronic infections or inflammatory processes. If this persists, it would be advisable to consult a healthcare provider for further evaluation.

Given your symptoms, it is important to consider that while localized issues can arise, they do not necessarily indicate a systemic immune dysfunction. However, if you are experiencing persistent symptoms or if they worsen, it would be prudent to seek medical attention. A healthcare provider can perform a thorough evaluation, including blood tests and possibly imaging studies, to rule out any underlying conditions.

In the meantime, here are some general recommendations to support your immune health:
- Nutrition: Ensure you are consuming a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Nutritional deficiencies can compromise your immune system.

- Hydration: Drink plenty of fluids to stay hydrated, which is essential for overall health and immune function.

- Rest: Prioritize sleep and rest, especially during your exam preparation. Sleep is crucial for immune health.

- Stress Management: Engage in stress-reducing activities such as exercise, meditation, or hobbies that you enjoy.

- Hygiene: Maintain good hygiene practices to prevent infections, especially during cold and flu season.

In conclusion, while your symptoms are concerning, they may not necessarily indicate a significant immune system issue. Monitoring your symptoms and seeking medical advice if they persist or worsen is the best course of action. Remember to take care of your overall health, especially during this stressful time of preparing for your university entrance exams.

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