Nasopharyngeal Cancer: Symptoms, Diagnosis, and Concerns - Otolaryngology

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Suspected nasopharyngeal carcinoma?


Hello doctor, about two weeks ago I discovered a lump in the lower side of my neck.
It is tender to the touch, and over time the lump has not increased in size and has slowly decreased.
As of now, the lump is still present, and the tenderness is not as severe as before.
I went to the hospital for a fine needle aspiration biopsy, and they found "pus." I have not experienced any nasal congestion, nosebleeds, ear pain, or headaches, but the doctor mentioned that this location does not rule out the possibility of nasopharyngeal carcinoma.
I am currently waiting for the biopsy report, which will take a week, but I am a bit worried, so I wanted to ask you.
Thank you.

Sen, 20~29 year old female. Ask Date: 2020/05/04

Dr. Zheng Jueyi reply Otolaryngology


Hello: Currently, it is not possible to make a determination; we must wait for the aspiration results to assess and treat.
Wishing you safety and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2020/05/04

More Info


Understanding nasopharyngeal cancer (NPC) involves recognizing its symptoms, diagnosis, and the concerns that arise during the evaluation process. NPC is a type of head and neck cancer that originates in the nasopharynx, the area located behind the nose and above the back of the throat. It is more prevalent in certain regions, particularly Southeast Asia, and is often associated with the Epstein-Barr virus (EBV).


Symptoms of Nasopharyngeal Cancer
The symptoms of NPC can vary widely, and some patients may not exhibit any noticeable signs in the early stages. Common symptoms include:
1. Lump in the Neck: As you mentioned, a lump in the neck can be a significant indicator. This lump may be due to swollen lymph nodes, which can occur when cancer spreads to nearby lymphatic tissue.


2. Nasal Symptoms: While you currently do not have nasal congestion or bleeding, these symptoms can occur in some patients. Other nasal symptoms may include a persistent runny nose or a feeling of fullness in the ear.

3. Hearing Loss: Due to the proximity of the nasopharynx to the ear, some patients may experience hearing problems.

4. Throat Symptoms: A sore throat, difficulty swallowing, or a sensation of something being stuck in the throat can also be present.

5. Facial Pain or Numbness: In advanced cases, patients may experience pain or numbness in the face.


Diagnosis of Nasopharyngeal Cancer
The diagnosis of NPC typically involves several steps:
1. Physical Examination: A thorough examination by an ENT specialist is crucial. They will look for any abnormalities in the throat and neck.

2. Imaging Studies: CT scans or MRIs may be used to visualize the nasopharynx and surrounding structures. These imaging studies help assess the extent of the disease.

3. Biopsy: A definitive diagnosis is made through a biopsy, which involves taking a sample of tissue from the suspected area. In your case, the fine needle aspiration (FNA) that yielded "pus" suggests that there may be an inflammatory process or infection, but it does not rule out malignancy.

4. Histopathological Examination: The biopsy sample will be examined microscopically to determine the presence of cancer cells. This is a critical step in confirming the diagnosis.


Concerns and Next Steps
While waiting for the biopsy results can be anxiety-inducing, it is essential to remain calm and informed. Here are some points to consider:
1. Understanding the Results: If the biopsy confirms NPC, the next steps will involve staging the cancer to determine how far it has spread. This will guide treatment options.

2. Treatment Options: Treatment for NPC often includes radiation therapy, chemotherapy, or a combination of both. The specific approach will depend on the stage of the cancer and the patient's overall health.

3. Follow-Up Care: Regardless of the outcome, follow-up care is crucial. If the biopsy shows benign results, monitoring the lump and any symptoms is essential. If cancer is diagnosed, a multidisciplinary team will work with you to develop a comprehensive treatment plan.

4. Emotional Support: It is normal to feel anxious during this time. Consider discussing your concerns with family, friends, or a mental health professional. Support groups for cancer patients can also provide valuable resources and emotional support.

5. Lifestyle Considerations: Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can help improve overall well-being and may support recovery.

In conclusion, while the possibility of nasopharyngeal cancer is concerning, it is important to await the biopsy results for a definitive diagnosis. If cancer is confirmed, early detection and treatment can significantly improve outcomes. Stay proactive in your healthcare, and do not hesitate to reach out to your healthcare provider with any questions or concerns as you navigate this process.

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