Could HPV and Fungal Test Results Vary Due to Doctor's Technique? - Obstetrics and Gynecology

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HPV and fungal sampling failure?


Hello, doctor.
I mainly want to ask if the results of HPV and fungal tests at the hospital could vary due to differences in the doctor's technique.
At the end of 2018, I had my first HPV test, referred to a large hospital A by a trusted private clinic.
They provided me with a paper report indicating inflammation, with about 3-4 types detected (presumably not including warts).
The doctor advised that I should continue monitoring for the next five years, as my body would eventually clear the virus.
At the end of 2019, I went to another large hospital B for a check-up due to excessive vaginal discharge, where I underwent a second HPV sampling and a fungal culture test.
I did not return to hear the results for various reasons.
In June 2020, due to the recent appearance of yellow-green discharge (with no sexual activity in the past three months), I returned to the same doctor at hospital B for an examination and to hear the results.
The doctor stated that both HPV and fungi were not detected.
However, because I still had yellow-green discharge, the doctor found it strange and decided to perform another fungal culture test.
The doctor seemed to conduct the procedure rather casually, using the speculum in a hasty manner and quickly taking the sample while occasionally chatting with the previous patient and nurse.
Given this, I am a bit concerned that the HPV and fungal tests at hospital B might not have detected the virus or fungi due to inadequate sampling by the doctor.
As for the fungi, I can manage that with medication.
I'm uncertain whether I should spend more money on another HPV test, considering it is not inexpensive...

bazin, 20~29 year old female. Ask Date: 2020/06/18

Dr. Wu Xianghui reply Obstetrics and Gynecology


There are several possible reasons, including: 1.
Autoantibody production.
2.
Insufficient sample collection or absence of HPV virus in the specimen.
3.
Issues with the testing equipment, among others.
It is recommended to consider switching to a different laboratory every other year or to undergo Pap smear testing annually.

Reply Date: 2020/06/18

More Info


The concern regarding the variability of HPV and fungal test results due to the technique of the healthcare provider is valid and deserves careful consideration. The accuracy of these tests can indeed be influenced by several factors, including the skill and technique of the healthcare provider performing the sampling, the quality of the sample collected, and the laboratory methods used for analysis.


HPV Testing
Human Papillomavirus (HPV) testing typically involves collecting cells from the cervix using a swab. The effectiveness of this test can be affected by how well the sample is collected. If the sample is insufficient or if the swab does not adequately collect the necessary cells, it may lead to false-negative results. This means that the test may indicate that HPV is not present when it actually is.
In your case, if the doctor at Hospital B performed the sampling in a hurried or careless manner, it is possible that the sample collected was not representative of the cervical cells, leading to a negative result. Additionally, HPV can be transient; many individuals clear the virus naturally over time. Therefore, if you had a previous positive result, it is possible that the virus was no longer detectable at the time of the second test.


Fungal Testing
Fungal infections, such as those caused by Candida species, are typically diagnosed through culture tests or microscopic examination of vaginal secretions. Similar to HPV testing, the accuracy of fungal tests can also be influenced by the technique used during sample collection. If the sample is not collected properly or if there is contamination, it may lead to inaccurate results.
In your situation, the doctor's approach during the second fungal test may have contributed to the results. If the sampling was done quickly and without proper technique, it could have resulted in a failure to detect an existing fungal infection.


Recommendations
Given your concerns about the accuracy of the tests performed at Hospital B, it may be prudent to consider a few options:
1. Repeat Testing: If you are still experiencing symptoms such as unusual discharge, it may be worthwhile to seek a repeat test at a different facility where you feel confident in the provider's technique. This could provide you with more reliable results.

2. Consultation with a Specialist: Consider consulting a gynecologist who specializes in HPV and fungal infections. They can provide you with a thorough examination and may suggest additional tests or alternative methods of testing that could yield more accurate results.

3. Regular Monitoring: Since HPV can be transient, regular monitoring through Pap smears and HPV testing as recommended by your healthcare provider is essential. This is particularly important if you have a history of abnormal results.

4. Education on HPV: Understanding that HPV is common and that most infections resolve on their own can help alleviate some anxiety. However, it is crucial to monitor for any potential complications, such as cervical changes.

5. Treatment for Symptoms: If you are experiencing symptoms like unusual discharge, it is important to address these with appropriate antifungal treatment, which can be prescribed by your healthcare provider.

In conclusion, while the technique of the healthcare provider can influence test results, it is also important to consider the natural course of HPV infections and the possibility of transient fungal infections. Regular follow-ups and open communication with your healthcare provider are key to managing your health effectively.

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