Loss of Appetite and Weight: What Tests Should You Consider? - Family Medicine

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In the past three weeks, there has been a loss of appetite, and weight has decreased by nearly 5 kilograms. What tests should be conducted?


Hello, Doctor.
I have been experiencing a loss of appetite, and over the past three weeks, I have lost nearly 5 kilograms.
I'm unsure if I should undergo any specific diagnostic tests or which specialty I should consult.
I am a 24-year-old male who just graduated from college.
After moving back to my hometown at the end of August, I will be starting graduate school in October.
Recently, I have been experiencing intermittent coughing and chest tightness for about 2-3 weeks.

On the other hand, I suspect that psychological factors may be contributing to my condition.
Since moving back home on September 1st, I have had a lot to organize and prepare for my studies abroad, and I have lost my social circle, often spending my days alone in my room.
Reflecting on my past experiences during summer and winter breaks in high school, this "isolated" lifestyle has indeed made me feel depressed and down, but I am unsure how to improve it.
If my issues are indeed related to my mood, it seems there are no medications available for that.
Regarding the tests I have undergone:
A.
This month, due to my cough and sudden chest pain (which occurred three days after playing a ball game), I visited a pulmonologist and had a chest X-ray that showed "Mild prominent bilateral lung markings."
B.
In May of this year, I had a complete blood test, eGFR, PLT, and UPCR, which were generally normal, except for a high platelet count of 469*10^3/ml.
This was similar to last year's count of 425*10^3/ml, so I doubt there are issues like leukemia or cancer.
Additionally, my white blood cell differential count was normal.
C.
In August of this year, an abdominal ultrasound indicated increased echogenicity in the liver, with a report suggesting mild fatty liver.
D.
A kidney X-ray in August was normal.
E.
An electrocardiogram in August showed early repolarization.
F.
An echocardiogram in August revealed mild mitral and tricuspid valve regurgitation.
G.
In May of last year, I underwent an upper endoscopy that showed acid regurgitation, mucosal breaks (less than 5mm) in the lower esophagus, hyperemic changes in the stomach antrum, and reflux esophagitis, Grade A by Los Angeles classification, along with superficial gastritis and easy belching.
H.
A colonoscopy performed in May of last year only showed internal hemorrhoids.
Since many conditions can affect appetite, I wanted to bring this up to seek your guidance.
I hope you can clarify whether any of my tests indicate potential underlying risks (especially since many of them were conducted months or even years ago) or suggest which specialty I should consult for further evaluation.

Liao Tongxue, 20~29 year old female. Ask Date: 2020/09/19

Dr. Ye Qianyu reply Family Medicine


Hello! Based on your description of decreased appetite and weight loss over the past three weeks, it is recommended that you bring your previous examination reports and visit a family medicine outpatient clinic for evaluation.

Reply Date: 2020/09/19

More Info


Loss of appetite and weight loss can be concerning symptoms, especially when they persist for several weeks. In your case, you've mentioned a significant weight loss of about 5 kilograms over three weeks, along with other symptoms like cough and chest discomfort. Given your age and the context of recent life changes, it’s essential to approach this situation holistically, considering both physical and psychological factors.


Physical Health Considerations
1. Medical History and Previous Tests: You have undergone various tests, including blood tests, chest X-rays, abdominal ultrasounds, and endoscopies, which have provided some insights into your health. The mild prominent bilateral lung markings on your chest X-ray could indicate some underlying respiratory issues, which may contribute to your cough and chest discomfort. The increased echogenicity of your liver suggests mild fatty liver disease, which can be associated with dietary habits and lifestyle factors.

2. Potential Causes of Appetite Loss: There are numerous medical conditions that can lead to loss of appetite, including:
- Gastrointestinal Disorders: Your history of gastroesophageal reflux disease (GERD) and superficial gastritis could be contributing to your symptoms. Acid reflux can cause discomfort that may deter eating.

- Psychological Factors: Stress, anxiety, and depression can significantly impact appetite. Your recent life changes, such as moving back home and preparing for graduate studies, may be contributing to feelings of isolation and depression.

- Infections or Chronic Conditions: Persistent cough and chest pain could indicate an underlying infection or chronic condition that may also affect your appetite.

3. Recommended Tests: Given your symptoms and history, consider the following tests:
- Complete Blood Count (CBC): To check for any signs of infection or anemia.

- Thyroid Function Tests: To rule out hyperthyroidism, which can cause weight loss and appetite changes.

- Liver Function Tests: To assess the health of your liver, especially given the fatty liver diagnosis.

- Pulmonary Function Tests: If respiratory issues persist, these tests can help evaluate lung function.

- Psychological Evaluation: If you suspect that your appetite loss is related to mental health, consider speaking with a mental health professional.


Psychological Health Considerations
1. Mental Health Impact: The transition from university to graduate studies, coupled with moving back home, can be stressful. Feelings of isolation and depression can manifest physically, leading to symptoms like loss of appetite and weight loss. It’s crucial to address these psychological aspects.

2. Coping Strategies: Engage in activities that promote mental well-being, such as:
- Physical Activity: Regular exercise can improve mood and appetite.

- Social Interaction: Try to reconnect with friends or family, even if virtually, to combat feelings of isolation.

- Mindfulness and Relaxation Techniques: Practices such as meditation, yoga, or deep breathing exercises can help manage stress.

3. Seeking Help: If you feel overwhelmed, consider reaching out to a mental health professional. Therapy can provide support and coping strategies to manage stress and anxiety.


Conclusion
In summary, your symptoms of loss of appetite and weight loss warrant a thorough evaluation that encompasses both physical and psychological health. Given your medical history and recent life changes, it’s advisable to consult a healthcare provider, preferably a primary care physician or a gastroenterologist, to discuss your symptoms and undergo the recommended tests. Additionally, consider seeking support for any psychological distress you may be experiencing. Addressing both aspects will be crucial in improving your overall health and well-being.

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