Medications During Pregnancy: Safety Concerns for Your Baby - Obstetrics and Gynecology

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Medications during pregnancy


I am currently 29 weeks pregnant and have a severe cold.
I visited an obstetrician who prescribed me NOSCAPINE, Keflex 500 mg, and Levocetirizine Dihydrochloride.
I would like to know if these medications will have any effects on the fetus.

Ru Ru, 20~29 year old female. Ask Date: 2020/12/04

Dr. Huang Yuande reply Obstetrics and Gynecology


The above medications can be used in moderation during pregnancy; however, antibiotics such as Keflex should not be prescribed for a common cold unless there is a bacterial infection.

Reply Date: 2020/12/04

More Info


When it comes to medication use during pregnancy, safety is a paramount concern for expectant mothers. The medications prescribed to you—Noscapine, Keflex (Cephalexin), Scanol (likely a brand name for a combination medication), and Levocetirizine—each have different safety profiles, and it's essential to understand their potential effects on both you and your developing baby.

1. Noscapine: This is a cough suppressant that is derived from opium poppy. It is generally considered to be safe during pregnancy, as there is limited evidence suggesting it poses a risk to the fetus. However, as with any medication, it should be used under the guidance of a healthcare provider, especially during pregnancy.

2. Keflex (Cephalexin): This is a cephalosporin antibiotic commonly used to treat bacterial infections. It is classified as a Category B medication by the FDA, which means that animal studies have not shown any risk to the fetus, and there are no adequate and well-controlled studies in pregnant women. Therefore, it is generally considered safe to use during pregnancy when prescribed by a healthcare professional.

3. Scanol: Without specific information on the active ingredients in Scanol, it is difficult to assess its safety. If it contains common over-the-counter medications like acetaminophen or ibuprofen, the safety profile may vary. Acetaminophen is generally considered safe during pregnancy, while ibuprofen is usually advised against, especially in the third trimester due to potential risks to the fetus. It is crucial to check the active ingredients and consult your healthcare provider regarding its use.

4. Levocetirizine: This is an antihistamine used to relieve allergy symptoms. It is classified as Category B, indicating that it is generally considered safe during pregnancy. However, it is always best to use it under the guidance of a healthcare provider, especially if you are experiencing severe symptoms.


Additional Considerations
- Consult Your Healthcare Provider: Always inform your healthcare provider about your pregnancy and any medications you are taking. They can provide personalized advice based on your medical history and the specifics of your pregnancy.


- Monitor Symptoms: If you experience any unusual symptoms or side effects while taking these medications, contact your healthcare provider immediately.

- Non-Pharmacological Approaches: In addition to medications, consider non-pharmacological approaches to manage your cold symptoms. Staying hydrated, using saline nasal sprays, and resting can help alleviate symptoms without the need for additional medications.

- First Trimester Caution: While you are currently in your third trimester, it is worth noting that the first trimester is often the most critical period for fetal development, and many medications can have different effects depending on the stage of pregnancy. Always discuss any concerns with your healthcare provider.

In summary, the medications you have been prescribed appear to be generally safe for use during pregnancy, but it is essential to consult with your healthcare provider for personalized advice and to ensure that they are appropriate for your specific situation. Your health and the health of your baby are the top priorities, and your healthcare provider can help you navigate any concerns you may have.

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