Can I Mix AHA with Water for Acne Treatment? - Dermatology

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Can A acid be mixed with water for application?


Previously, my doctor prescribed me a 0.1% third-generation retinoid to treat acne.
The doctor advised me to use only a pea-sized amount and not to apply too much.
However, I find it difficult to spread it evenly over my entire face.
Can I mix it with a little water before applying? I previously read that it can be mixed with lotion, but I'm concerned that lotion might be too oily for me since I have oily skin.
Thank you.

pigg, 20~29 year old female. Ask Date: 2021/01/15

Dr. Wu Yuxin reply Dermatology


You can apply moisturizer first, followed by tretinoin.

Reply Date: 2021/01/15

More Info


When it comes to using AHA (Alpha Hydroxy Acid) or A酸 (which is often referred to as retinoids or tretinoin in the context of acne treatment), it is essential to follow the guidance provided by your healthcare provider. In your case, you have been prescribed a third-generation A酸 (tretinoin) at a concentration of 0.1% for treating acne. Your doctor advised you to use a pea-sized amount, which is a common recommendation to prevent over-application and potential irritation.

Mixing AHA with water is a topic that often arises among individuals with oily skin or those who find it challenging to spread the product evenly across their face. While it is technically possible to dilute AHA with water, it is not generally recommended. The primary reason is that diluting the product may reduce its effectiveness. AHA and retinoids are formulated to work at specific concentrations, and altering that concentration could hinder their ability to penetrate the skin and deliver the desired results.

If you are concerned about the texture and spreadability of the A酸, there are a few alternatives you might consider:
1. Layering Technique: Instead of mixing the A酸 with water, you could apply a light, oil-free moisturizer first. This can help create a barrier that makes it easier to apply the A酸 without it feeling too heavy or greasy. Look for a moisturizer that is labeled as non-comedogenic, which means it won’t clog your pores.

2. Application Method: You might also try applying the A酸 to slightly damp skin. After cleansing your face, pat it dry gently, leaving it a little moist. This can sometimes help with the spreadability of the product.

3. Gradual Introduction: If you are new to using A酸, consider starting with a lower frequency of application (e.g., every other night) to allow your skin to adjust. Over time, as your skin becomes accustomed to the treatment, you can increase the frequency.

4. Consult Your Dermatologist: If you continue to have difficulty applying the A酸 evenly, it would be wise to discuss this with your dermatologist. They may have specific recommendations tailored to your skin type and concerns.

Regarding your concern about mixing A酸 with other products, it is crucial to be cautious. While some individuals mix A酸 with moisturizers, as you mentioned, this can sometimes lead to increased oiliness, which may not be suitable for oily skin types. Always prioritize products that are lightweight and non-comedogenic.

In summary, while mixing AHA with water is possible, it is not advisable due to potential dilution of the active ingredient. Instead, consider using a light moisturizer or adjusting your application technique to improve spreadability. Always consult with your healthcare provider for personalized advice, especially when dealing with prescription medications like A酸. Your skin's health and the effectiveness of your treatment should always come first.

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